⚕️ New research with @lshtm-tbmod.bsky.social shows how the most effective public health interventions against #TB would be population-wide ones, like mass vaccination programmes and screenings Read the @lshtm.bsky.social story 🔽 www.lshtm.ac.uk/research/cen...

⚽️ Only 1 day to go until our Men’s Health Soccer Event! Join us tomorrow for soccer, learn the facts about TB, and discover why early testing matters. Together we can reduce stigma, protect our health, and build stronger communities. 💙 #MensHealth #EndTB

New publication led by Mphatso Phiri: Drivers of sex differences in Mycobacterium tuberculosis immunoreactivity among adolescents and adults in Blantyre, Malawi link.springer.com/article/10.1... @uofgshw.bsky.social @lightontb.bsky.social @kchorton.bsky.social #TB #Episky 🛟🧪

Drivers of sex differences in Mycobacterium tuberculosis immunoreactivity among adolescents and adults in Blantyre, Malawi - BMC Global and Public Health

Background Sex differences in Mycobacterium tuberculosis (Mtb) exposure likely contribute to sex differences in tuberculosis (TB) burden. However, population-level age- and sex-specific patterns of Mt...

link.springer.com

Really great to see this messaging and action by @tbproof.bsky.social to raise awareness and reach men affected by #TB! ⚽️

TB Proof @tbproof.bsky.social · 2w ago

4 days to go! ⏳⚽ Did you know? Talking about TB can help save lives. How are you raising awareness or supporting someone affected by TB? Share your story below. Every conversation, every test, every act of support helps end TB. 💚 #EndTB

Our new paper in @nathealth.nature.com shows that population-level #TB interventions are likely to have more meaningful impact on disease burden than interventions that only reach routinely diagnosed individuals or their households. www.nature.com/articles/s44... 1/7

Global impact and cost-effectiveness of tuberculosis interventions - Nature Health

A modelling analysis at a global scale estimates that three interventions (vaccination, community-wide screening and prison screening programmes) could prevent more than 10% of tuberculosis cases betw...

nature.com

Academic clinical jobs @lshtm.bsky.social for people in UK clinical training Clinical Lecturers 1) Infectious Diseases (ST3-6) tinyurl.com/4vbjwrkr 2) Paediatrics (ST4-7) tinyurl.com/2hajhbs3 3) Public Health (ST3-5) tinyurl.com/yzd5cmxa Clinical Fellow in Primary Care (ST1) tinyurl.com/mpsmk7zk

Men continue to experience more than twice the prevalence of TB than women across LMICs. This LIGHT Consortium-supported systematic review and meta-analysis adds to the evidence for gender-responsive TB prevention, diagnosis, and care. 📖 journals.plos.org/plosmedicine... #TB #EndTB #GlobalHealth

Who is most likely to miss out on TB diagnosis and treatment? This LIGHT impact case study shows how better data uncovered important differences between men, women & young people helping shape fairer TB policies, strengthen national reporting & improve care. Read: light.lstmed.ac.uk/resources/li...

Data-driven Insights Into Sex and Gender Disparities in Tuberculosis: Insights From The LIGHT Research Programme

This case study highlights how LIGHT addressed these challenges through gender-responsive and equity-focused research across Kenya, Malawi, Nigeria and Uganda. LIGHT combined primary and secondary

light.lstmed.ac.uk

New preprint suggests that combining clinic and community-based approaches is key to maximising the cost-effectiveness of #tuberculosis active case finding in South Africa 🇿🇦 Read more 👉 www.medrxiv.org/content/10.6...

Projected population level impact and cost-effectiveness of clinic and community-based tuberculosis screening approaches

The South Africa National Department of Health have set ambitious targets to scale up TB testing, focusing primarily on clinic attendees. In the context of declining funding for TB care and prevention...

medrxiv.org

New publication now out in @lancetgh.bsky.social! New #TB #vaccines are being trialled in older adolescents and adults, and we comment on the advantages and challenges of including younger adolescents who have historically been excluded. www.thelancet.com/journals/lan...

Inclusion of young adolescents in policy development for new tuberculosis vaccines

The infant tuberculosis vaccine, BCG, prevents severe tuberculosis disease, but protection is rarely durable beyond childhood. New tuberculosis vaccines are being developed for the prevention of infec...

thelancet.com

Poverty is a major driver of TB.Conditional cash transfers combined with counselling improve pre-treatment loss to follow-up.In this economic analysis our modelling projections show that this intervention is cost-effective and can reduce incidence and mortality. www.sciencedirect.com/science/arti...

Cost-effectiveness of conditional cash transfers with pre- and post-test tuberculosis counselling in South Africa: a modelling analysis

Tuberculosis (TB) disproportionately affects low-income populations due to socioeconomic barriers. Conditional cash transfers (CCTs) are promising str…

sciencedirect.com

New: Risk & cause of death among people living with #HIV admitted to hospital Overall mortality remains unacceptably high (16%) & probably hasn’t changed since 2000 AIDS-related conditions (72%) esp. #TB (27%) main cause of death dx.doi.org/10.1002/jia2... @uofgshw.bsky.social #IDSky #TBSky 🧪🛟

New evidence is shaping TB policy and care in Uganda 🇺🇬 Through LIGHT, researchers at Gombe and Mityana Hospitals tested gender-responsive TB screening to improve diagnosis and care for men. 📄 Read the evidence brief: mli.mak.ac.ug/light-eviden... 🎥 Watch the Uganda video: youtu.be/BuM0MVoQnoQ?...

Transforming TB Care in Uganda: LIGHT Consortium & Makerere University Lung Institute Impact Story

YouTube video by LIGHT Consortium

youtu.be

It's been 10 years since we published our first review of sex differences in #TB prevalence. In this update, we found men remain twice as likely as women to have TB, and disparities have likely widened over time. journals.plos.org/plosmedicine...

Peter MacPherson@petermacp.bsky.social · 2mo ago

We updated our review of sex diff. in #TB prevalence In 102 surveys (4.7M participants) men were 2x as likely to have TB than women Evidence consistent with sex differences widening over time 🧪🛟 journals.plos.org/plosmedicine... @nswartwood.bsky.social @kchorton.bsky.social @uofgshw.bsky.social

So...what would happen to the global TB epidemic if we "eliminated" undernutrition? Our paper out now @lancetgh.bsky.social, where we combined estimates from our review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(www.sciencedirect.com/science/arti...)

Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study

Current efforts to reduce global tuberculosis incidence have proved insufficient, highlighting that urgent action is needed to address underlying modi…

sciencedirect.com

Out now! Our preprint reviewing effects of extreme weather events on TB. papers.ssrn.com/sol3/papers.... @mjsaunder.bsky.social with Lauren Linde & Leo Martinez @bostonu.bsky.social & many others @tb-lshtm.bsky.social @lshtm-tbmod.bsky.social @lshtm-planet.bsky.social

Budding infectious disease modellers: We're running our intermediate-level infectious disease modelling short courses at the London School of Hygiene and Tropical Medicine. Each course is 4 days, and we're running them over the first two weeks of September.

In our latest paper in @plosmedicine.org, we explore trade-offs in diagnostic algorithm, coverage, and duration of community screening for #TB, highlighting the importance of symptom-agnostic approaches and the need for strategies to sustain impact when screening ends. plos.io/4tuD2SM

PLOS Medicine@plosmedicine.org · 4mo ago

In this mathematical modelling study, Katherine Horton & co assess #TB community screening approaches & their estimated effects on TB incidence & mortality, concluding that methods that capture both infectious & non-infectious TB are needed to achieve sustained case reductions🧪 plos.io/4tuD2SM

In this systematic review & meta-analysis, Mortazavi & colleagues (@petermacp.bsky.social) investigate urban vs rural differences in #TB prevalence between 2000 and 2024 in 26 low- and middle-income countries, finding that TB epidemics have become increasingly urbanized 🧪 #MedSky plos.io/3O79BqY

Urban and rural prevalence of tuberculosis in low- and middle-income countries: A systematic review and meta-analysis

In a systematic review and meta-analysis, Seyed Alireza Mortazavi and colleagues investigate urban versus rural differences in adult pulmonary tuberculosis prevalence between 2000 and 2024 in 26 low- ...

plos.io

Great to see this work led by @alexandra-richards.bsky.social with @lightontb.bsky.social in @commsmed.nature.com. Further evidence that addressing gender disparities in TB burden and care are necessary for both an equitable response *and* an effective response. ⬇️

Peter MacPherson@petermacp.bsky.social · 4mo ago

New study led by @alexandra-richards.bsky.social. Reducing men’s TB risk and improving treatment access could have big impacts on #TB incidence and deaths for men, women, and children. www.nature.com/articles/s43... @kchorton.bsky.social @uofgshw.bsky.social @lightontb.bsky.social

Join us for the closing webinar of the LIGHT research programme exploring gender-responsive approaches to TB care. 📅 31 March 2026 |⏰ 12:00–13:30 BST Hear key findings from 6 years of global research, community-led insights, and what’s next for scaling impact. 👉 Register: shorturl.at/QVLDX

Our analysis of #TB exposure and transmission patterns is now in @pnas.org. @petedodd24.bsky.social and I found a majority of TB transmission globally is attributable to contact with adult men, while contributions to transmission by age are more variable across regions. www.pnas.org/doi/10.1073/...

Katherine Horton@kchorton.bsky.social · 10mo ago

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

🗞️ Recent study with @lshtm-tbmod.bsky.social modelled the potential impact of funding cuts to TB #PublicHealth initiatives from international donors Already implemented USAID cuts could cost $7.5 billion (USD) for healthcare systems & people living with TB Read 🔽 www.lshtm.ac.uk/research/cen...

World TB Day Symposium 2026: 2 weeks to go Join us in London or online on 24 March for the annual UCL/LSHTM symposium Topics include: • Beyond the lungs • Global trends & health systems • The potential for AI Details and registration: www.ucl.ac.uk/tb/events/wo... @tb-lshtm.bsky.social

New paper in @plosmedicine.org led by @aportnoy.bsky.social builds on our analysis of the potential epidemiological impacts of reductions in donor funding for #TB to show the economic burden on affected individuals and their households.

Allison Portnoy@aportnoy.bsky.social · 5mo ago

With Nick Menzies and @lshtm-tbmod.bsky.social, our new modeling study estimated how reductions in donor funding could affect the economic burden of #TB on patients, especially among the poorest households journals.plos.org/plosmedicine...

In this modeling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries 🧪 #MedSky #TB plos.io/4ryyBFX

The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study

In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...

plos.io

Our recent modelling study found that the estimated impact of new TB vaccines depends on the efficacy to prevent infectious asymptomatic TB. Read more in our paper out now in @plosmedicine.org! journals.plos.org/plosmedicine...

Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis: A modelling study

Hira Tanvir and colleagues estimate the potential impact of new tuberculosis vaccines under three scenarios of efficacy and conclude that to achieve the greatest impact, vaccines must prevent asymptom...

journals.plos.org

Really excited to share that this work from @aschwalbc.bsky.social estimating the burden of viable Mtb infection is now published in @plosmedicine.org!

Alvaro Schwalb@aschwalbc.bsky.social · 6mo ago

1/📢 In our new publication, we estimate that in 2022, 134 million people worldwide had a recent Mycobacterium tuberculosis (Mtb) infection and were at high risk of progressing to TB disease. Read the full paper in PLOS Medicine (tinyurl.com/mtbinfection). #TBSky

Our new paper on strategies for implementing a potential new #TB #vaccine in South Africa is now published in @plosglobalpublichealth.org! doi.org/10.1371/jour...

Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa

Several tuberculosis (TB) vaccines intended for adults and adolescents are in late-stage clinical trials, but there is limited research into how a new TB vaccine would be introduced. South Africa is a...

doi.org

PhD position (London, UK) Real-time modelling of infectious disease outbreaks. with @sbfnk.bsky.social @anne-cori.bsky.social @seabbs.bsky.social at @epiforecasts.io @cmmid-lshtm.bsky.social More details: http://iddjobs.org/jobs/2440