Chlorophyll keeps the world breathing - ever wondered how it is made? @orestissavva.bsky.social covers work from @dmitryshvarev.bsky.social et al. #preprint “This work adds to our fundamental understanding of the world around us...” #PlantBiology #preLight⬇️ prelights.biologists.com/highlights/s...

Structure of chlorophyll synthase in complex with the LHC-like protein HliD - preLights

Chlorophyll keeps the world breathing - ever wondered how it is made?

prelights.biologists.com

We really appreciate the time and work that @orestissavva.bsky.social put into preparing the PreLights article, and his thoughtful questions were a nice avenue for Charlotte to expand on her work. Thanks to BioRxiv for highlighting this resource.

bioRxiv & medRxiv@biorxiv-medrxiv.bsky.social · 3mo ago

Community Reviews are science in real time! Check out this new and recent example of open feedback in action: @cb99-lewis.bsky.social et al.’s preprint just got reviewed by a community-organized group through preLights! 📄 doi.org/10.64898/202... (@dbhella.bsky.social) #Preprints #openRxiv

Cats: the ultimate pets and scientific heroes. 🐱 Studying feline viruses to identify innovative solutions to prevent human infections. #preprint by @cb99-lewis.bsky.social, @dbhella.bsky.social & team #microbiology #preLight by @orestissavva.bsky.social: prelights.biologists.com/highlights/i...

Inhibition of VP2-mediated entry: a potential antiviral strategy to treat or prevent calicivirus disease - preLights

Cats: the ultimate pets and scientific heroes. Researchers are studying feline viruses to identify innovative solutions to prevent human infections

prelights.biologists.com

Cryo-EM ligand building using AlphaFold3-like model and molecular dynamics pubmed.ncbi.nlm.nih.gov/40788932/ #cryoEM

Cool and collected: Advances in sample preparation for cryo-electron microscopy pubmed.ncbi.nlm.nih.gov/40784122/ #cryoEM

Human ribosome interactions reframe neomycin toxicity www.biorxiv.org/content/10.1101/2025.07.22.666027v1 #cryoEM

We have written up a tutorial on how to run BindCraft, how to prepare your input PDB, how to select hotspots, and various other tips and tricks to get the most out of binder design! github.com/martinpacesa...

Time-resolved cryo-electron microscopy can resolve protein motion on millisecond or even microsecond timescales, but the need for highly specialized tools and skills limits the method’s reach www.nature.com/artic...

Freeze frame: cracking molecular motion

Nature - Time-resolved cryo-electron microscopy can resolve protein motion on millisecond or even microsecond timescales, but the need for highly specialized tools and skills limits the method’s...

nature.com

New research shows that simply changing how a reaction vessel is positioned on a magnetic stirrer can significantly change a reaction's speed and product quality, influencing the reproducibility of results. #ChemSky #ScienceSky #EduSky

Position of flask on magnetic stirrers can drastically affect reproducibility of experiments

Comprehensive examination reveals improper siting of reaction vessels can affect catalyst formation, alter nanoparticle formation and change yields

chemistryworld.com

Structural studies on ribosomes of differentially macrolide-resistant Staphylococcus aureus strains pubmed.ncbi.nlm.nih.gov/40490363/ #cryoEM

A great read on how flexibility and air–water interface interactions impact SPA cryo-EM data quality! Congratulations @isobelhirst.bsky.social @stemuench.bsky.social @scarfflab.bsky.social and the team!

Iso Hirst@isobelhirst.bsky.social · last yr.

I’m very happy to share my first paper on the effects of AWI interactions and flexibility on SPA data quality! Thank you to everyone on the team 🤩 www.sciencedirect.com/science/arti...

Illuminating ubiquitination mechanisms: How cryo-EM has shed light on Cullin RING E3 ligase function pubmed.ncbi.nlm.nih.gov/40311545/ #cryoEM

Missed any of the Fragment-Screen webinars with @instruct-eric.bsky.social? Take a look at them here, with talks from @ceitec.eu, @ebi.embl.org, IBM Research and FFULisboa! fragmentscreen.org/news-and-eve...

Protein structure prediction via deep learning: an in-depth review pubmed.ncbi.nlm.nih.gov/40248099/ #cryoEM

Unraveling the proton-sensing mechanisms of G protein-coupled receptors: Insights from cryogenic electron microscopy studies pubmed.ncbi.nlm.nih.gov/40250408/ #cryoEM

The code & camera-ready version of our #ICLR2025 paper on "Multi-domain Distribution Learning for De Novo Drug Design" are now available 📚 Paper: openreview.net/forum?id=g3V... 💻 Code: github.com/LPDI-EPFL/Dr... (1/4)

The structural diversity of psychedelic drug actions revealed pubmed.ncbi.nlm.nih.gov/40108183/ #cryoEM

Structure-guided design of partial agonists at an opioid receptor pubmed.ncbi.nlm.nih.gov/40082451/ #cryoEM

Protein bL38 facilitates incorporation of uL6 during assembly of the 50S subunit in Flavobacterium johnsoniae pubmed.ncbi.nlm.nih.gov/39997215/ #cryoEM

"Norovirus replication, host interactions and vaccine advances" www.nature.com/articles/s41...

Norovirus replication, host interactions and vaccine advances - Nature Reviews Microbiology

In this Review, the authors highlight recent advances in human norovirus biology, including classification, strain-specific differences in cell entry and innate immune responses. They also highlight p...

nature.com

HflX-mediated drug resistance through ribosome splitting and rRNA disordering in mycobacteria pubmed.ncbi.nlm.nih.gov/39913204/ #cryoEM

Beautiful work! 🧬🧶 www.science.org/doi/10.1126/...

Molecular basis of mRNA delivery to the bacterial ribosome

Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the Shine-Da...

science.org

The binding of RbgA to a critical 50S assembly intermediate facilitates YphC function in bacterial ribosomal assembly pubmed.ncbi.nlm.nih.gov/39658043/

Apparently, everyone is moving to Blue Sky now...