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Rebecca J Hall

@drrebeccajhall.bsky.social

Royal Society University Research Fellow | University of Manchester | Evolution, symbiosis, metabolism

277 Posts1555 Follower961 Folgt
Arkadiy Garber@ironark.bsky.social · last wk.

The last chapter of my PhD work is now live on MBE. This has been an incredible project, combining genomics, proteomics, as well as transcriptomics that resolves total mRNA from ribosome-associated mRNA (which we infer to be in the process of translation).

Molecular Biology and Evolution@molbioevol.bsky.social · 4w ago

@ironark.bsky.social et al. measured transcript abundance, ribosome-associated RNA, and protein abundance in bacterial endosymbionts, suggesting a mechanism for aberrant pseudogene-derived protein removal. 🔗 doi.org/10.1093/molbev/msag153 #societyjournal #evobio #molbio

MBE | The transcriptional and translational outcomes for pseudogenes in bacterial endosymbionts
STCmicrobeblog@stcmicrobeblog.bsky.social · 4w ago

how 𝘚𝘰𝘥𝘢𝘭𝘪𝘴-derived endosymbionts deal with pseudogenes prior to genome reduction john (formerly @mcsymbiont on 𝕏, not on bsky) has been digging in his favorite rabbit hole for 30 years now, and his lab still finds new things... thx for pointing this out, @evgenii-protasov.bsky.social 🙏 #SymbioSky

Of Terms in Bi­ol­ogy: Trans-Trans­la­tion

by John McCutcheon, Janie and Christoph — This could become a very short explainer of the term "trans-trans­lation", as gi­ven by Vioque and de la Cruz in their mini­review: "Trans-trans­lation is…

smallthingsconsidered.blog

Evgenii Protasov@evgenii-protasov.bsky.social · 4w ago

The transcriptional and translational outcomes for pseudogenes in bacterial endosymbionts #microbiology #pseudogene #ribosome #proteomics #MicroSky doi.org/10.1093/molb...

Evgenii Protasov@evgenii-protasov.bsky.social · 2w ago

Neffella xylocopae gen. nov., sp. nov., a novel host-specific gut symbiont of Xylocopa carpenter bees in the family Orbaceae #microbiology #NewSpecies #bees #taxonomy #MicroSky doi.org/10.1099/ijse...

Neffella xylocopae gen. nov., sp. nov., a novel host-specific gut symbiont of Xylocopa carpenter bees in the family Orbaceae

Bee-associated Orbaceae species aid in the metabolism of plant polysaccharides, toxic sugars and urea and stimulate the immune system. In honeybees and other eusocial bees, microbial transmission occu...

doi.org

Nancy Moran@nancy-moran.bsky.social · last mo.

A step forward in discovering Buchnera's key to the aphid's heart, published today! Thanks to Jerry Maeda and other authors--a great team -- and to the helpful reviewers #SymbioSky doi: doi.org/10.1038/s415...

A secreted endosymbiont protein essential for colonizing host cells - Nature

SyeA was present in the Buchnera ancestor, is secreted into the host cytoplasm, is homologous to secreted effectors of bacterial pathogens and is essential for Buchnera transmission.

doi.org

Paul Hoskisson 🧫 🦠🐸@paulhoskisson.bsky.social · last mo.

really lovely piece of work from @raufs.bsky.social et al., Complex multicellularity is linked with expanded specialized metabolite production in microorganisms www.nature.com/articles/s41...

Complex multicellularity is linked with expanded specialized metabolite production in microorganisms - Nature Microbiology

The evolutionary emergence of complex multicellularity in bacteria and fungi, such as the ability for mycelial growth, is strongly associated with increased genomic carriage of biosynthetic machinery ...

nature.com

Seána Duggan@seanaduggan.bsky.social · 2mo ago

🗞️New Paper🗞️ We show that #Candida & #Staph cooperate via copper handling - with fungal copper uptake & bacterial copper export shaping the community. @mrccmm.bsky.social @microbiologysociety.org @universityofexeter.bsky.social www.microbiologyresearch.org/content/jour...

Copper-driven mutualism of Candida albicans and Staphylococcus aureus interkingdom biofilms

Although fungi and bacteria commonly co-exist within polymicrobial communities, the molecular mechanisms underlying their interactions are still not well understood. Here, we show that the fungus Cand...

microbiologyresearch.org

Rowan Green@rowancallumg.bsky.social · 2mo ago

Where are mutations most likely to happen in the genome? @mattjago.bsky.social has answers! This paper is also a masterclass in simple visualizations of complicated ideas. I really enjoyed getting deep into these results as a middle author 🧬

Matt Jago@mattjago.bsky.social · 2mo ago

Our work characterizing how mutational bias is influenced by the local sequence context beyond trinucleotides is out now @pnas.org! We also showed which motifs are most prone to mutations caused by strand misalignment, revealing several new hotspots! 🧬 www.pnas.org/doi/10.1073/...

Peter Mulhair@petermulhair.bsky.social · 2mo ago

Latest paper lead by Asia Hoile with @peterhox.bsky.social is out! 🦋 Nymphalid butterflies have reduced forelegs. Gene expression patterns show support for more palp-like genes involved in sensory processes in the forelegs relative to the walking legs. doi.org/10.1111/imb....

Distinctive gene expression in the reduced first thoracic legs of a nymphalid butterfly

Transcriptome analysis reveals that the small non-walking front legs of a butterfly have distinct gene expression to the four walking legs. Reduced front legs express a gene with putative mechanosen...

doi.org

Microbial Systems Ecology Lab@micsysecolab.bsky.social · 2mo ago

Very excited to share our new preprint, led by Alyssa Henderson! We ask why auxotrophy is so widespread in bacteria, and find that phylogeny is the dominant predictor of autotrophy, as opposed to environmental context. Check it out! 👇

Amino acid auxotrophy is a feature of a distinct bacterial lifestyle across environments

Amino acid auxotrophy, the loss of biosynthetic potential for an amino acid, is a highly prevalent feature of microbial life, yet the evolutionary processes driving its distribution in nature remain u...

doi.org

Matt Hutchings@matthutchings.bsky.social · 3mo ago

Great to see this published in the @microbiologysociety.org collection on Actinomycetes Conserved regulator MtrA directly activates ectoine biosynthesis and expression of BldM and WhiI to trigger sporulation in response to hyperosmotic stress www.microbiologyresearch.org/content/jour... 1/2

MtrAB activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae

The MtrAB two-component system is a master regulator of antibiotic biosynthesis in Streptomyces species. MtrA is also required for sporulation under certain growth conditions, which means that on some...

microbiologyresearch.org

Nela Nikolic@nelani.bsky.social · 3mo ago

We are hiring! 🔬🧫 Join our lab at the Uni Southampton as a Research Technician working on bacteria-phage interactions to develop therapies for hard-to-treat infections. 2-year post Deadline: 27 May 2026 Position start date: 1 July 2026 or shortly after Apply: jobs.soton.ac.uk/Vacancy.aspx...

Dr Nela Nikolic receives Springboard funding to develop approaches to tackle bacterial infections

Dr Nela Nikolic receives Springboard funding to develop approaches to tackle bacterial infections

southampton.ac.uk

Rebecca J Hall@drrebeccajhall.bsky.social · 3mo ago

Wonder how this will affect movement of ECRs. If an institution can only put one candidate forward, would they prioritise current postdocs or incoming ones. Might there be any consideration of how long each postdoc has left on their contract or other factors. Stressful.

Kirsty Grainger @kirstygrainger.bsky.social · 3mo ago

If you have a BBSRC Early Independence Fellowship outline in, check your inbox. Please give professional services teams a few days to design demand management processes as we're finding out the same time as you. The outlines per institute data provided is super interesting; 15 awards available 👀👀👀👀

UKRI – Biotechnology and Biological Sciences Research Council Annex A – Maximum Number of Applications to the 2026 round of the BBSRC Early Independence Fellowship scheme per HEI These figures have been calculated based on submissions to the 2021 Research Excellence Framework (REF) with the number of Early Independence BBSRC Fellowship applications permitted related to the FTE staff numbers included within each institutions REF submission as follows: Academic organisations who did not submit to the REF and are not identified within the grouping are permitted to submit one application to this opportunity. Table UKRI – Biotechnology and Biological Sciences Research Council Annex A – Maximum Number of Applications to the 2026 round of the BBSRC Early Independence Fellowship scheme per HEI These figures have been calculated based on submissions to the 2021 Research Excellence Framework (REF) with the number of Early Independence BBSRC Fellowship applications permitted related to the FTE staff numbers included within each institutions REF submission as follows: Academic organisations who did not submit to the REF and are not identified within the grouping are permitted to submit one application to this opportunity. Table Higher Education Institution (HEI) Number of outline applications Maximum number of applications to this opportunity Aberystwyth University 8 1 Aston University 4 1 Babraham Institute 1 1 Brunel University London 1 1 Cardiff University 8 2 Cranfield University 4 1 Durham University 5 1 Earlham Institute 1 1 Edge Hill University 2 1 Harper Adams University 3 1 Heriot-Watt University 3 1 Imperial College London 27 2 Institute of Cancer Research 3 1 James Hutton Institute 1 1 John Innes Centre 3 1 King's College London 28 2 Lancaster University 3 1 Leeds Beckett University 1 1 London School of Hygiene…
Daniel Padfield@padpadpadpad.bsky.social · 3mo ago

BBSRC Early Independence Fellowships had an Outline stage this year to try help with amount of peer review. Turns out they received 586 applications, a 110% increase on 2025, and only typically fund 15 a year. They are cancelling this stage and going straight to full app with an institutional sift.

Michael Brockhurst@brockhurstlab.bsky.social · 3mo ago

Less than 1 week to apply for this postdoc! If you want to find out more about the project have a look at our recent preprint: www.biorxiv.org/content/10.6... #mevosky

biorxiv.org

Michael Brockhurst@brockhurstlab.bsky.social · 3mo ago

Why does antibiotic resistance evolution vary between patients? Come to @officialuom.bsky.social @mermanchester.bsky.social to help us find out! 2.5 year @wellcometrust.bsky.social postdoc position in experimental evolution Closing 15 May. Apply here: www.jobs.manchester.ac.uk/Job/JobDetai...

Susan Schlimpert@s-lab.bsky.social · 3mo ago

Dear PhD students and postdocs — we want to hear about your science firsthand at our annual Early Career Microbiologists Mini-Symposium @johninnescentre.bsky.social (UK) this September. For more information and to apply: www.jic.ac.uk/event/early-...

Early Career Microbiologists Mini-Symposium 2026 | John Innes Centre

The Department of Molecular Microbiology is organising a one and a half day Early- Career Microbiologists Mini-Symposium. The symposium will be held from Tuesday 22nd – Wednesday 23rd September 2026.

jic.ac.uk

Alejandro Manzano Marín@amanzanom.bsky.social · 3mo ago

Pentapartite symbiotic system in #Legendrea loyezae by @filiphusnik.bsky.social & co. doi.org/10.21203/rs.... #SymbioSky #protistsOnSky

A novel mitochondrion-related organelle and complex endosymbiosis in a rare anaerobic single-celled predator

Anaerobic single-celled eukaryotes illustrate the remarkable diversity of adaptations to life without oxygen, including multiple mitochondrial reductions and various symbiotic interactions with prokar...

doi.org