"proteasome-derived defence peptides could provide an untapped source of natural antibiotics..." 🤯 www.nature.com/articles/s41...

Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature

Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...

nature.com

Clams as biosensors of water quality 😄

Joanna Bagniewska@joannabagniewska.com · 2y ago

Hardly new info, but BSky should know: Warsaw's water quality is monitored by eight clams with magnets attached to their shells. If contamination in the water causes the clams to close, the magnets trigger an alarm and shut off the city's water supply. Thank you, little guardian molluscs. 🧪🌏🚰

Ensuring rigour of low-biomass microbiome research www.nature.com/articles/s41...

This excellent interactive tutorial on misleading data visualizations explores the idea of a "counter chart" — the graph you draw in response to refute a misleading claims flowingdata.com/projects/dis...

Defense Against Dishonest Charts

This is a guide to protect ourselves and to preserve what is good about turning data into visual things.

flowingdata.com

How to "program" living cells.🧫 In 2000, physicists (incl. Michael Elowitz) made bacteria blink on-and-off every 150 minutes. Their experiment, which blended mathematics and wet-lab methods, launched the field of synthetic biology. Learn how they did it in my first interactive story!

Out now! We consolidated >600 Dutch yeast and characterised their activity against spoilage yeasts and relevant human and plant pathogens, focusing on yeasts that secrete antifungal proteins. Great resource for biocontrol and beyond. pubmed.ncbi.nlm.nih.gov/39875071/

Amazing work from Farren Isaacs team at Yale - reducing E.coli's genetic code down to only using a single stop codon. A 62 codon GRO with lots of potential for applications. www.nature.com/articles/s41...

Engineering a genomically recoded organism with one stop codon - Nature

Ochre, a strain of Escherichia coli engineered to have a single stop codon, enables reassignment of four codons for non-degenerate functions, such as incorporation of non-standard amino acids into pro...

nature.com

#Microbes Saving Lives & Reducing Suffering—led by KenTimmis, this is a call to action for understanding and exploiting microbes & their role in helping humans at the face of current challenges as a global society @microbiotech.bsky.social enviromicro-journals.onlinelibrary.wiley.com/doi/full/10....

Microbes Saving Lives and Reducing Suffering

Click on the article title to read more.

enviromicro-journals.onlinelibrary.wiley.com

Two PhD positions available in my group: 1) Investigating ribosome biology in V.natriegens by single particle tracking with @ryanfseipke.bsky.social @aleksponjavic.bsky.social Deadline 28 February. www.findaphd.com/phds/project... 1/2

Building a fluorescent toolbox for exploring translation in Vibrio natriegens at University of Leeds on FindAPhD.com

PhD Project - Building a fluorescent toolbox for exploring translation in Vibrio natriegens at University of Leeds, listed on FindAPhD.com

findaphd.com

We cannot join #SMPS4 but hot off the press our nanopore work to monitor CAS9 reactivity and its off-target effects. pubs.acs.org/doi/10.1021/...

Solid-State Nanopore Real-Time Assay for Monitoring Cas9 Endonuclease Reactivity

The field of nanopore sensing is now moving beyond nucleic acid sequencing. An exciting avenue is the use of nanopore platforms for the monitoring of biochemical reactions. Biological nanopores have b...

pubs.acs.org

👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.

Join us Jan. 23, 17:45 for the first 2025 LSN event! 🧬 Designing de novo tRNAs for Genetic Code Expansion Amir Guppy 🧪 Harnessing synbio tools for solving crucial biotech questions Dr. Anastasiya Kishkevich events.humanitix.com/copy-of-lond...

London SynBio Network 6

London SynBio afterwork talks and networking event on Thursday 12th of December

events.humanitix.com

Happy New Year everyone. Just a reminder that there are 3 days left to apply for a BBSRC-funded PhD position with myself and Julie Aspden on ribosome synthetic biology!

Eszter Csibra@ecsibra.bsky.social · 2y ago

Looking for a PhD in molecular/synthetic biology? Interested in RNA, protein synthesis or molecular machines? Currently advertising a BBSRC-funded PhD position on engineering novel methods for ribosome control. Details below. Please don't hesitate to get in touch if you'd like to know more.

Nominations for the 2025 Dorothy Bishop Award are now open!

Thoroughly enjoyed Next-Gen Synthetic Biology #NGSB24 in Ghent. A special blend of incredible speakers and laid back forum to chat science. Halfway home with a head buzzing with ideas and a lengthy reading list for next week.👩‍🔬📚 Thanks to the organisers! @vibtrainconf.bsky.social

I'm writing up a brief history of the tidyverse? What do you want to know about it? #rstats

Looking for a PhD in molecular/synthetic biology? Interested in RNA, protein synthesis or molecular machines? Currently advertising a BBSRC-funded PhD position on engineering novel methods for ribosome control. Details below. Please don't hesitate to get in touch if you'd like to know more.

Delighted to find, as a recent cat parent, that our cats are promising scientists. Here is Woody demonstrating that cats are non-Newtonian liquids… kind of. He will write up his findings as soon as nap time is over. Maybe.

Join us Dec. 12, 17:45 for the final LSN event of 2024! 🧬 ⏭️ Directed evolution of molecular chaperones towards aggregation-prone proteins ComeStellio 🏥 Engaging cancer patients on their attitudes towards microbiome engineering @kimberleyaowen.bsky.social events.humanitix.com/london-synbi...

London SynBio Network 5

London SynBio afterwork talks and networking event on Thursday 12th of December

events.humanitix.com

Late registration for Gogec is now open till 21 Dec. Looking forward to seeing many of you (and your projects) there! Register at the link ⬇️ tally.so/r/wzzAX1

Gogec 2025 Team Registration

Made with Tally, the simplest way to create forms.

tally.so

📰 Hot off the press at @naturecomms.bsky.social: RNA language models predict mutations that improve RNA function www.nature.com/articles/s41... Congrats to @kshulgina.bsky.social @jhdcate.bsky.social and coauthors on a great C-GEM + @innovativegenomics.bsky.social collaboration! #NSFfunded #RNAsky

Time for a proper intro: 👋 I am a group leader @ Leeds, focused on the study and engineering of translation control in bacteria. Our interests span 🦠 Synthetic biology 🧬 Protein synthesis 🎨 Fluorescence 🧮 Quantitative biology and 📈 Data analysis. Lots going on over the next few weeks, stay tuned!

Exciting post doc opportunity: we are seeking a post doc to work with us and @ProfTomEllis on large DNA engineering in mammalian cells funded by @ChanZuckerberg. Come and join us at @ImperialChemEng! Apply at the link below: www.imperial.ac.uk/jobs/search-...

Started creating a synthetic biology starter pack. Still missing many so reply here if I forgot you or someone else. go.bsky.app/SjfpxTK #synbio

@calin.bsky.social Great start to the synthetic biology starter pack list .. Would you mind adding me?

🦋 New to BlueSky? 🧪 Interested in science? 👀 Wanna find posts by scientists in specific fields? 📃 Here’s a list of +220 science-related feeds and their associated hashtags. #AcademicSky #PhDSky

BlueSky Science-Related Feeds

docs.google.com

Waves of new BlueSky arrivals in last few days! I’ve been tracking starter packs relevant to molecular/mechanistic/genetic/cellular…etc biology Hope it’s helpful but warning: now a v long thread! Probably the last time I can do this...

For #WorldJellyfishDay and the first prompt, dangerous, for Blobfest month of #InsertAnInvert2024 it’s a smack of jellyfish! 🧪🐡🪼 The collective noun for a group of jellyfish is a "smack". This amuses me, because I imagine them smacking their tentacles together in some sort of deepsea high five.🧵

An interesting new observation of the natural history of mitochondria tells us for the first time that there are two distinct types of mitochondria, one specialized for biochemical synthesis, the other for energy metabolism. This nontechnical video tells a fascinating story.

A new kind of mitochondria

YouTube video by nature video

youtu.be

With special mention to the Headless Project one..

RedPen/BlackPen@redpenblackpen.bsky.social · 2y ago

My first 12 #inktober2024 #CreativeCryptids. Some are mysterious, some are monstrous, some are villainous, all are fun. #sciart