While Ed can’t make #Nido2026, the lab is well-represented by Max Erdmann, and @rebee.bsky.social ! They will be sharing some of the labs findings on coronavirus replication! Catch Max’s talk tomorrow (Wed) at 3:25, and Rebee’s poster C-0036
Ed Emmott
@edemmott.bsky.social
#RNA #Virology & single-cell #Proteomics |Professor of Virology & Proteomics/Wellcome CDA fellow in C4pr_liv /livuniISMIB | He/Him | Personal account - lab account: emmottlab@bsky.social Web: emmottlab.org
Funded PhD studentship on equine tendon homeostasis/ageing with single-cell proteomics for Oct 2026 start! Open to both vets, and non-vets, though the funder offers an enhanced stipend for vets.
Funded PhD opportunity! (UK students only due to funder restrictions). Investigating cellular heterogeneity in tendon homeostasis and ageing using single-cell proteomics. Deadline 31st July. Project is a collaboration between the Peffers, Emmott and Thorpe labs on equine tendons. Start Oct 2026.
In other lab news, Ed was promoted to Professor of Virology & Proteomics. Huge thanks to the team for all their work and support! And to the various mentors and supporters who have helped along the way. We have lots more exciting science coming in the near future!
John Cohen has done a much tidier write up here, also referencing work in progress by the Oxford Vaccine team, Moderna and Serum Institute of India www.science.org/content/arti...
Vaccine experts debate options to combat outbreak of unusual Ebola strain
Small monkey experiments raise some hopes—and many questions
science.org
We do not currently have a vaccine for Bundibugyo ebolavirus. BUT! There are vaccine candidates that have ben tested in animals and could go forward more quickly to human trials. Eg VesiculoVax doi.org/10.1093/infd... and another VSV-based vaccine journals.plos.org/plosntds/art...
Early bird registration still available! Come join for what is always an excellent and very friendly meeting.
We are delighted to inform you that BSPR 2026 will be held at the @ebi.embl.org campus in Cambridge from the 13th to the 15th of July. Make sure to save the data and join us for the a meeting full of great science focused on British & Irish Proteomics. #proteomics #BSPR2026 #massspectrometry
New preprint from the lab!
New preprint! Current T7-based MNV reverse genetics can be performed by co-transfecting plasmids encoding T7 RNA polymerase and vaccinia capping enzymes. We see a further 100-1000-fold boost in titres by incorporating CD300lf-expressing BSR-T7 cells into this system. www.biorxiv.org/content/10.6...
We have a PhD studentship available!
Funded PhD studentship (UK students only) available on clinical proteomics, application deadline 22nd March for Oct 2026 start! This project seeks to understand treatment responses to exacerbations experienced by people with CF using proteomics. www.findaphd.com/phds/project...
Congrats to Dr @stephenholmes.bsky.social on passing his PhD viva today! Thanks to examiners Al Darby and @mtrost.bsky.social!
Update on UKRI funding situation. Summary: it is mostly bad news, and with significant uncertainties around new funding model.
‘Grave’ concerns over applicant-led funds at UK research councils. www.researchprofessionalnews.com/rr-news-uk-r...
This project would not have been possible without the incredible Liverpool Roller Birds, and the wonderful @emmottlab.bsky.social at @liverpooluni.bsky.social, and with support from the @microbiologysociety.org Outreach & Engagement Grant!
🚨 Big news! We’re thrilled to announce the release of both the Behind-the-Scenes Mini-Doc and the Full Recording of Antiviral Roller Skating! 🛼✨ Now you can watch the mini-doc to see how it all came together behind the scenes: youtu.be/0nevSD1wrdg And the full performance: youtu.be/mp995EBB3Bo
New preprint on flavivirus-host interactions with friend and collaborator Armando who spent a couple of months visiting the lab to do the interactomics with us.
Another new preprint! This time looking at flavivirus NS5 interactions with our collaborator Armando Arias - www.biorxiv.org/content/10.6...
Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis https://www.biorxiv.org/content/10.64898/2025.12.01.691577v1
See Markella’s thread for more information on our new scpImaging preprint!
I’m excited to share our preprint introducing scpImaging, a workflow we developed to improve data quality in single-cell proteomics (SCP) by repurposing the microscopy images generated during cell isolation with the cellenONE platform www.biorxiv.org/content/10.6...
New preprint. Thread to follow!
New preprint from the lab, and joint first authors @biomarkella.bsky.social and @stephenholmes.bsky.social! Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis www.biorxiv.org/content/10.6...
#Postdoc alert! We are looking for motivated individual with experience in computational systems biology to join our NetworkCommons initiative to benchmark and democratise network contextualisation methods across multiple applications. Deadline Dec 17th link here: tinyurl.com/yrrzxa94
Postdoctoral fellow - Petsalaki Group - NetworkCommons
Your group The Petsalaki, Saez-Rodriguez (EMBL-EBI) and Korcsmáros (Imperial College) groups develop cutting-edge computational and AI approaches to unravel cellular signalling and gene regulation fro...
tinyurl.com
New preprint! More landing soon!
New preprint: Viral protease-mediated polyprotein processing in human astroviruses Great collaboration with Lulla lab. And the first of @leandroxneves.bsky.social proteolysis stories. More coming soon! www.biorxiv.org/content/10.1...
We’ve been considering creating an announcement mailing list for #PRIDE @pride-ebi.bsky.social; to share new features, releases, datasets, known issues, and more. If you think this would be useful, please Like and RT!
New preprint: IFIT3 controls IFIT1 accumulation and specificity preventing self mRNA targeting during the innate immune response. www.biorxiv.org/content/10.1... Led by Renata Fleith from the Sweeney lab.
biorxiv.org
Rare personal update - back to work after two weeks in one of my favourite cities (Kyoto), now married to my best friend Anna!
I see @lancetmicrobe.bsky.social from the lancet group published a study yesterday under pilot study ethics. This is great. What is concerning is that a competing study was rejected a month ago from @ebiomedicine.bsky.social, AFTER PASSING PEER REV, as pilot study ethics insufficient. What changed?
Not my area, but amazing news on treating neurodegenerative diseases today - www.bbc.co.uk/news/article...
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
bbc.co.uk
A huge thank you to everyone who joined us and helped make the Festival such a success!! 💙 #BritishScienceFestival #BSF25 @britsciassoc.bsky.social Read more and see our highlights here >>> brnw.ch/21wVNyw
Science comes alive at the 2025 British Science Festival - University of Liverpool News
Science comes alive at the 2025 British Science Festival
brnw.ch
This was great fun, and excellent questions at the Q & A after the show. Looking forward to sharing the recordings soon.
The British science festival 2025 has started in Liverpool and @idb-virology.bsky.social and the team are looking forward to welcoming visitors to the Unity theatre this evening for some antiviral roller skating! @antiviral-rskating.bsky.social www.unitytheatreliverpool.co.uk/whats-on/ant...
We are still buzzing from our show! Here’s some snaps of what you missed… in case you were wondering…. Huge thank you to the whole production team and the people who made this happen! @microbiologysociety.org @britsciassoc.bsky.social @emmottlab.bsky.social @livuninews.bsky.social #BSF25
The British science festival 2025 has started in Liverpool and @idb-virology.bsky.social and the team are looking forward to welcoming visitors to the Unity theatre this evening for some antiviral roller skating! @antiviral-rskating.bsky.social www.unitytheatreliverpool.co.uk/whats-on/ant...
Antiviral roller skating! | British Science Festival 2025 - Unity Theatre
Run time: 18.30 – 19:15 Throwback: it’s summer 2020, lockdowns are looming, you’ve bought yourself a pair of roller skates to cure your boredom… Swoop over to see the Liverpool Roller Birds dance agai...
unitytheatreliverpool.co.uk
Our first post on here and it's a doozy 😍🤩. Our epic piece on #sarbecovirus host range. #virology #sars2 #covid #vaccines. Enjoy and please repost. www.biorxiv.org/content/10.1...
Understanding the future risk of bat coronavirus spillover into humans: correlating sarbecovirus receptor usage, host range, and antigenicity.
Sarbecoviruses interact with their receptor, angiotensin converting enzyme 2 (ACE2), via the receptor binding domain (RBD) of Spike, the immunodominant target for neutralising antibodies. Understandin...
biorxiv.org