Christoph Schwarz
@electro-like.bsky.social
Nephrologist, interest in: electrolyte disorders and kidney stones
Ooh @kidneyint.bsky.social goes there Fast www.kidney-international.org/article/S008... Slow www.kidney-international.org/article/S008... Hyponatremia controversies #NephSky
Hyponatremia treatment guidelines: a necessary course correction
The optimal treatment of hyponatremia has been debated for >50 years. It is now widely accepted that in severe hyponatremia (<120 mmol/L), the rate of correction should not exceed 8 mmol/L per 24 hour...
kidney-international.org
The latest issue of nephSAP is here. Explore Vol. 25, No. 1, Electrolytes and Acid-Base Disorders, for the latest advances in electrolyte and acid-base disorders. Listen to the companion podcast on hypernatremia with guest editor Biff F. Palmer, MD. 📖: https://nephsap.org 🎧: bit.ly/podcastASN
Wow! 🆕🔥🔴Multicenter OL NI RCT Oral fosfomycin (3 g once daily) was noninferior to continued intravenous therapy with carbapenems or BLBLIs when used as oral transition therapy for complicated UTIs caused by ESBL-producing Enterobacterales #IDSky #utisky academic.oup.com/cid/article-...
Fosfomycin as Oral Transition Therapy Versus Continued Intravenous β-Lactams for Complicated Urinary Tract Infections Caused by Extended-Spectrum β-Lactamase–Producing Enterobacterales: A Multicenter,...
Switching from intravenous antibiotics to oral fosfomycin was noninferior to continuing intravenous therapy for complicated urinary tract infections caused
academic.oup.com
Genetic #Screening of Patients With Inherited #FanconiSyndrome #VisualAbstract by Denisse Arellano https://www.kireports.org/article/S2468-0249(26)02808-1/fulltext
Exome sequencing in patients with medullary sponge kidney academic.oup.com/ndt/article-... very interesting study on the genetics of MSK
Exome sequencing in patients with medullary sponge kidney
AbstractBackground. Medullary sponge kidney (MSK) is characterized by precalyceal dilatation of the renal tubules. This entity is associated with recurrent
academic.oup.com
First data of the TTVguideIT RCT presented @ERA26 in Glasgow 🏴 Personalized Immunosuppression 💊 by Torque Teno 🦠 virus in kidney TX is safe and might help reducing Tacrolimus #TTVguide @fredhaupenthal.bsky.social 👏
Perfect timing for @kireports.bsky.social to publish the IgG4 review as the @nejm.org publishes this RCT of Obexelimab www.nejm.org/doi/full/10....
Swapnil Hiremath 🍁🇨🇦@hswapnil.medsky.social · 2mo agoExcellent review of IgG4 disease and treatment in KIR
In the Literature commentary by Eleanor Lederer and Naim M. Maalouf: The Role of Altered Mineral Metabolism in Kidney Stone Disease: Is Vitamin D the Key? bit.ly/4o9NbDa (FREE) Article in @jci.org ⬇️
The Role of Altered Mineral Metabolism in Kidney Stone Disease: Is Vitamin D the Key?
Kidney stones are common, affecting 10%-15% of the population.1 The foundation for the current therapy to prevent kidney stones is based on the principle that supersaturation of solutes in the urine p...
bit.ly
Journal of Clinical Investigation@jci.org · 12mo agoGenetic susceptibility to kidney stone disease: unveiling pathogenesis and potential therapeutic targets: buff.ly/6e4HlKB Shiwei Li et al. provide a commentary on Martine P. Roudier et al.: buff.ly/LqnXOHS
The future is here CAR-T cells and kidney transplants in highly sensitized patients Phase 1 trial, N = 2, www.nejm.org/doi/full/10.... Research letter, N = 1, www.nejm.org/doi/full/10....
Kidney Transplantation in Two Highly Sensitized Candidates after CAR T-Cell Therapy | NEJM
HLA sensitization poses a major challenge to kidney transplantation for patients with end-stage kidney disease, especially for highly sensitized candidates. Attempts at antibody elimination (desens...
nejm.org
"...this review found little to no benefits from use of calcium, vitamin D, or combined supplementation on the prevention of fractures and falls." www.bmj.com/content/393/... via @bmj.com
Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis
Objective To assess the effect of calcium, vitamin D, or combined supplementation on fractures and falls in adults. Design Systematic review and meta-analysis. Data sources Trials included in system...
bmj.com
Top Cited Article: Navigating the multifaceted intricacies of the Na+-Cl− cotransporter, a highly regulated key effector in the control of hydromineral homeostasis A. V. Rioux et al. https://ow.ly/IEx450YZtZ9
In this edition, @nephroseeker.medsky.social breaks down the Bayesian voodoo behind removing evil humor www.nephjc.com/news/2026/sh... #EMIMCC #NephSky
NephJC Short: Bayesian leash: How a prior walked the Tigris across the finish line — NephJC
Can polymyxin B hemadsorption truly shift the fate of septic shock, or is the outcome already written?
nephjc.com
🚨CONGRATS @ksusztak.bsky.social @bernhard-dumoulin.bsky.social & team on a fantastic @nature.com paper! DKD isn’t 1 disease! #spatial & #singlecell data reveal distinct injury niches—including B cell–rich immune subtype linked to faster progression. #Nephrology #PrecisionMedicine #NephSky #MedSky 🧪
The many roles of the calcium-sensing receptor in the kidney | American Journal of Physiology-Renal Physiology | American Physiological Society journals.physiology.org/doi/full/10.... Very nice review !!
The many roles of the calcium-sensing receptor in the kidney | American Journal of Physiology-Renal Physiology | American Physiological Society
The calcium-sensing receptor (CaSR) is a central regulator of renal mineral homeostasis and tubular function. Since the discovery of its expression in the kidney, numerous studies have demonstrated th...
journals.physiology.org
New publication: the Vienna group at @meduniwien.ac.at demonstrates the predictive value of #TTV load during months 4 to 12 post-transplant for the incidence of malignancy during years 2 to 5 post-transplant. academic.oup.com/ndt/advance-...
Torque teno virus is predictive for malignancies after kidney transplantation
AbstractBackground and hypothesis. Malignancy, driven by the effects of immunosuppression, is a major complication following kidney transplantation. The wi
academic.oup.com
Pleased to share this study by Nabil Sweis et al. in AJP-Renal where we report for the first time a comparison of Tolvaptan vs hypertonic saline to increase plasma sodium in normal volunteers doi.org/10.1152/ajpr... @feinberg.northwestern.edu @nu-nephrology.bsky.social
🚨 #NephJC short 🩳from @kidneyboy.bsky.social The PUSH trial! 😉Can a wink, a nudge & a push encourage kidney stone formers to drink more fluid to prevent recurrence 🪨? (Hint: have 💦 behavioral trials worked in CHF or PCKD?) #NephSky #MedSky www.nephjc.com/news/2026/4/2/nephjc-short-the-push-trial
NephJC Short: The Push Trial — NephJC
Water, water everywhere. Can a wink, a nudge and a push increase water intake to decrease kidney stone formation?
nephjc.com
If you are a Vienna resident or plan a spring visit to the most liveable city in the World: come join us at our booth at the Researchers Night at @meduniwien.ac.at and learn about the superhero-virus #TTV: langenachtderforschung.at/station/6326
Viren können Superheroes sein oder wie kann man das Immunsystem messen? - #LNF26 Lange Nacht der Forschung
Wir erforschen wie man die Stärke des Immunsystems messen kann. Zuerst erklären wir Ihnen, anhand eines Posters und eines Animationsfilms wie das funktioniert und warum uns das TT Virus dabei hilft. D...
langenachtderforschung.at
Function 🔙 Throw Back Thursday: Eaton at al. demonstrated that kidney-specific knockout of #Dmxl1 disrupted V1–V0 assembly, reduced proton pumping, and raised urine pH, supporting it as a mammalian #V-ATPase assembly factor. Read the full article doi.org/10.1093/func...
Proactive vs Reactive DDAVP: The Clamp Finally Faces an RCT Thank you Thai Air Force for doing the trials that need to be done! pbfluids.com/2026/03/proa...
Saline Doesn’t Ruin Hyponatremia Labs (and it might help) How many times have you been evaluating a patient in the ED and bemoaned the sneaky liter of saline they got before anyone sent some urine for analysis. Turns out it doesn't ruin the labs at all. pbfluids.com/2026/03/sali...
Saline Doesn’t Ruin Hyponatremia Labs (It Might Help)
A study by Dr. Chienwichai highlights challenges in diagnosing hyponatremia due to undisclosed intravenous saline administration. While saline infusion does not obscure urine biochemical tests, it …
pbfluids.com
The HIT (Hyponatremia Intervention Trial) is finally out! #hyponatremia #nephrology evidence.nejm.org/doi/10.1056/...
A Randomized Trial of Targeted Hyponatremia Correction in Hospitalized Patients
Chronic hyponatremia is associated with adverse outcomes, including falls, neurocognitive disorders, and mortality, but whether hyponatremia itself increases morbidity and mortality, or is simply a...
evidence.nejm.org
We advance the understanding and importance of Ca/PO4/FGF23 in Dent disease journals.lww.com/cjasn/abstra...
journals.lww.com
This #ASNKidney360 study explored the relationship between arterial and venous blood gas parameters to develop formulas for estimating arterial values from venous samples. Read more: kidney.pub/KID1113
Thank you @asnpublications.bsky.social for posting our paper on the transformation of venous to arterial blood gas. To facilitate calculations, I developed an App “Venous to Arterial Blood Gas” available for free (apps.apple.com/us/app/venou...) @nu-nephrology.bsky.social @feinberg.northwestern.edu
Venous to Arterial Blood Gas App - App Store
Download Venous to Arterial Blood Gas by Daniel Batlle on the App Store. See screenshots, ratings and reviews, user tips, and more apps like Venous to Arterial…
apps.apple.com
ASN Publications@asnpublications.bsky.social · 6mo agoThis #ASNKidney360 study explored the relationship between arterial and venous blood gas parameters to develop formulas for estimating arterial values from venous samples. Read more: kidney.pub/KID1113
Parathyroid hormone suppression profiles following oral calcium challenge in kidney transplant recipients doi.org/10.1016/j.kint.2025.11.019 #NephSky #MedSky #OpenAccess -Early calcium–PTH dynamics could define PT-HPT subtypes & 🔓 personalized treatment
