Elvira Forte
@elviraforte.bsky.social
Scientist passionate about fibrosis, inflammation & single-cell omics technologies. Science writer/advisor helping bridge biology and AI at https://www.ericandwendyschmidtcenter.org/. Consultant at www.lifescienceeditors.com Former: NatureCVR, jacksonlab
1/2 A new preprint from the #EricandWendySchmidtCenter introduces a framework for pretraining foundation models with linear rather than quadratic computational complexity, overcoming a long-standing barrier to modeling long-range dependencies at scale.
bioRxiv Bioinfo@biorxiv-bioinfo.bsky.social · 2w agoMulti-modal foundation model with whole-slide attention enables transferrable digital pathology at single-cell resolution https://www.biorxiv.org/content/10.64898/2026.07.31.741265v1
The preprint detailing the results of the #SchmidtCenter Cancer Immunotherapy Machine Learning Competition is online! @broadinstitute.org #MachineLearning #CancerImmunotherapy #ComputationalBiology #PerturbSeq #AI4Science #VirtualCell www.biorxiv.org/content/10.6...
Exciting new study from #EricAndWendySchmidtCenter fellow Josephine Yates, et al., introducing SpatialFusion: a lightweight #multimodal #FoundationModel combining #histopathology and #SpatialTranscriptomics for pathway-informed spatial #niche mapping. 👉 httpis://doi.org/10.64898/2026.03.16.712056
doi.org
Very interesting paper from the Frangogiannis’s lab — #Fibroblast -Specific Loss of #TGF-β Signaling Mediates Lipomatous Metaplasia in the Infarcted #Heart (and cardiac rupture) www.ahajournals.org/doi/10.1161/... @ahajournals.bsky.social @einsteinmededu.bsky.social
Fibroblast-Specific Loss of TGF-β Signaling Mediates Lipomatous Metaplasia in the Infarcted Heart | Circulation
BACKGROUND: In patients surviving myocardial infarction, adipose tissue infiltration within the scar is a common pathological finding and has been suggested to contribute to dysfunction and arrhythmog...
ahajournals.org
A technology that played a key part in saving millions of lives during the pandemic should be celebrated. Yet in the US, research into mRNA vaccines is being cut. While sadly not unexpected, it’s irresponsible as we argue in our editorial this week 🧪 www.nature.com/articles/d41...
Cancelling mRNA studies is the highest irresponsibility
The rest of the world is not following the US government’s dangerous path, and will stick with the technology that helped the world out of the COVID-19 pandemic.
nature.com
🚨 New preprint from the #EricAndWendySchmidtCenter! 🚨 "MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities" www.biorxiv.org/content/10.1... @broadinstitute.org #SingleCell #PerturbSeq #OpticalPooledScreen #AIinBiology #ScienceNews #CompBio
This tiny device can shrink dangerous blood clots. It’s called the ‘milli-spinner’ and its invention was partly an accident…
Can you go from protein sequence to a generated image of protein localization? New work from the Uhler lab says yes, and it is generalizable to unseen proteins and more than one cell type. I'm excited for work moving us toward virtual cell models.
Nature Methods@natmethods.nature.com · last yr.PUPS - prediction of unseen proteins' subcellular localization - uses machine learning models to predict the localization of unseen proteins in unseen cell lines from sequence and cellular images. www.nature.com/articles/s41...
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏 youtu.be/8YhJM6zxYDw?...
Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company
youtu.be
PUPS - prediction of unseen proteins' subcellular localization - uses machine learning models to predict the localization of unseen proteins in unseen cell lines from sequence and cellular images. www.nature.com/articles/s41...
EXPOSED: Never seen before footage reveals the catastrophic impacts caused by bottom trawling ❌ @oceanauk.bsky.social www.youtube.com/watch?v=IzG9...
OCEAN WITH DAVID ATTENBOROUGH | BOTTOM TRAWLING OFFICIAL CLIP | IN CINEMAS NOW | Altitude Films
YouTube video by Altitude Films
youtube.com
Exciting news...Nature Methods is hiring a new editor! This exciting and dynamic role will be shared with the Nature Research Cross-Journal Editorial Team. Apply here by June 1! springernature.wd3.myworkdayjobs.com/SpringerNatu...
a yellow sign that says we 're hiring
ALT: a yellow sign that says we 're hiring
media.tenor.com
Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis www.nature.com/articles/s41...
Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis - Nature
Inhibition of a cardiac stroma-enriched mechanosensor, SRC—in concert with suppression of the TGFβ pathway—potentiates the reversal of fibroblast activation and alleviates contractile dysfunction in f...
nature.com
David Liu receives Breakthrough Prize in Life Sciences. Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. www.broadinstitute.org/news/david-l...
David Liu receives Breakthrough Prize in Life Sciences
Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine.
broadinstitute.org
Thrilled that our work on coronary dominance made the cover of @cellpress.bsky.social! This beautiful image is thanks to the incredible work of @pamrc.bsky.social! 😍 #CardioSky www.cell.com/cell/fulltex...
🌟 Few hours left to submit your abstract for the Annual Meeting of the Society (3-4 July 2025, University of Surrey, Guildford). Great programme, even better people...and a murder mystery at dinner! www.microcirculation.org.uk/75th-annual-... 🌟
75th Annual Meeting of the British Microcirculation and Vascular Biology Society
University of Surrey, GuildfordThursday 3rd and Friday 4th July 2025 Registration Abstract Submission Contact Organising Committee Click below to download flyer BMVBS MembershipMembers (before…
microcirculation.org.uk
This week, I have the privilege of interviewing Dr. Elisabeth Bik (@elisabethbik.bsky.social) in a special two-part series. We discuss her rich professional experience and path to data sleuthing. This is part I .https://www.podbean.com/eas/pb-9p4ye-1865e2f #science #research #integrity #data
Dr. Elisabeth Bik says question the data!-Part I
On this this week's episode, I have the pleasure and privilege of interviewing Dr. Elisabeth Bik in a special two-part series. We discuss her rich professional experience and her path to data sleuthin...
podbean.com
So many good suggestions in this insightful piece by Dennis J Hazelett. “The only way to give structure to your thoughts is to write them. Writing.Is.Thinking” @naturebiotech.bsky.social www.nature.com/articles/s41...
An open letter to graduate students and other procrastinators: it’s time to write
Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write
nature.com
Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH. Such work is exemplified by Prof Anna Greka @broadinstitute.org in a new Ground Truths podcast. Open-access, w/ transcript, video, no ads erictopol.substack.com/p/anna-greka...
Anna Greka: Molecular Sleuthing for Rare Diseases
Listen now | Finding the Mechanisms and the Basis for Potential Cures
erictopol.substack.com
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...
I heard about this interesting story a couple of years ago at an AHA meeting @ahascience.bsky.social. It's great to see it published @CellSystems. Congratulations @shovalmiyara.bsky.social, @eldadtzahor.bsky.social @urialonlab.bsky.social et al!
Shoval Miyara@shovalmiyara.bsky.social · last yr.It’s finally here! My PhD work, five years in the making, is now published @CellSystems @cellpress.bsky.social 🚨 Cold and hot fibrosis define clinically distinct cardiac pathologies. www.cell.com/cell-systems...
We started writing/posting Snippets a week ago, and our third one is up now, about tissue clocks and aging, written by Katrina Woolcock with a great image by Gloria Fuentes, both colleagues at Life Science Editors. Have a look! www.lifescienceeditors.com/2025/02/13/t...
Tissue clocks derived from histological signatures of biological aging enable tissue-specific aging predictions from blood - Scientific editing and writing experts - Life Science Editors
Scientific editing and writing experts for manuscripts and grants
lifescienceeditors.com
Checkout "Snippets" - the brainchild of our editor extraordinaire @sfmatheson.bsky.social www.lifescienceeditors.com/snippets/
Snippets - Scientific editing and writing experts - Life Science Editors
"Scientific editing and writing experts for manuscripts and grant
lifescienceeditors.com
Doing a little catch-up posting with the Let's Get Coffee series. Today I reflect on my chat with @elviraforte.bsky.social and her thought-provoking question! www.podbean.com/eas/pb-r9pgp...
Let's Get Coffee! Elvira Forte Episode
In this episode of "Let's Get Coffee", I sit back and ponder Elvira's question and read a passage from Ulysses by the 19th Century English poet, Alfred Lord Tennyson. As always, your questions and inp...
podbean.com
A total of $12 million in grant funding is available to fund 3 investigators/investigative teams proposing novel uses of Artificial Intelligence to revolutionize cardiovascular and cerebrovascular/brain health and health care delivery. Learn more: professional.heart.org/en/research-...
Novel Artificial Intelligence Approaches to Advance Cardiovascular and Cerebrovascular/Brain Health
Research funding opportunity focused on novel AI approaches to advance cardiovascular and cerebrovascular/brain health
professional.heart.org
#Schmidt_Center publication: Hannah Schlueter and Caroline Uhler present a method to automatically detect #gene-expression patterns related to #lineage progression from paired #single-cell data, across different biological systems: broad.io/PORCELAN @naturecomms.bsky.social @broadinstitute.org
Integrating representation learning, permutation, and optimization to detect lineage-related gene expression patterns - Nature Communications
Recent barcoding technologies allow the reconstruction of a cell’s lineage tree while capturing paired transcriptomic data. Here, the authors present a statistical method to automatically detect gene ...
broad.io
