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Eugenio Contreras

@eugecc.bsky.social

PhD Immunology student #UNAM. Passionate for science and the immune system. Interested in scientific discussion and the creation of space for science diffusion and education. #Mexican #OpenScience #OpenBoxScience @openboxscience.bsky.social

34 Posts1786 Follower1107 Folgt
Paula Licona@licona-limonlab.bsky.social · last mo.

What an incredible way to celebrate our recent publication in Nature Immunology! Our work is now accompanied by a News & Views article, and I honestly couldn't be more proud or grateful. @eugecc.bsky.social www.nature.com/articles/s41...

TIF1γ holds the line against regulatory T cell plasticity - Nature Immunology

A mechanistic understanding of how regulatory T cell plasticity is controlled remains lacking. A study shows that TIF1γ modulates this plasticity by restraining β-catenin signaling.

nature.com

Anna Salamero Boix@asalboix.bsky.social · last mo.

"TIF1γ holds the line against regulatory T cell plasticity" www.nature.com/articles/s41... Referring to the most recent study by @eugecc.bsky.social @licona-limonlab.bsky.social

TIF1γ holds the line against regulatory T cell plasticity - Nature Immunology

A mechanistic understanding of how regulatory T cell plasticity is controlled remains lacking. A study shows that TIF1γ modulates this plasticity by restraining β-catenin signaling.

nature.com

ImmuNoah's Ark (Noe Rodriguez)@immunoah.bsky.social · last mo.

Great to see this story from the @licona-limonlab.bsky.social Lab and @eugecc.bsky.social out! It was really interesting seeing how the project grew. Congrats! 🥳

Waggoner Lab@labwaggoner.bsky.social · last mo.

TIF1γ is a critical regulator of Treg cell stability that restrains β-catenin–TCF7 signaling, thereby preserving Foxp3 expression and preventing inflammatory reprogramming @natimmunol.nature.com www.nature.com/articles/s41...

Paula Licona@licona-limonlab.bsky.social · last mo.

Today, I can finally share some incredibly exciting news. Our work, "TIF1γ regulates stability of regulatory T cells during inflammation," has been published in Nature Immunology. www.nature.com/articles/s41590-026-02603-6

TIF1γ regulates stability of regulatory T cells during inflammation - Nature Immunology

This study identifies TIF1γ as a critical regulator of regulatory T cell stability during inflammation. By restraining β-catenin–TCF7 signaling, TIF1γ preserves Foxp3 expression, prevents inflammatory...

nature.com

Open Box Science @openboxscience.bsky.social · 5mo ago

OBS Immunology Seminar| Young Investigator Highlight 'Novel approaches to enhance the anti-tumor CD8 T cell response' Zachary S. Buchwald, MD PhD Assoc. Prof. of Rad. Onc. Emory University School of Medicine 🎙️@danmcmanus123.bsky.social Thurs, April 9th, 2026 12pm ET | 11am CT | 9am PT Zoom👇️

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Daniela Robles-Espinoza@daniela-oaks.bsky.social · 7mo ago

We are very happy to see our study finally appear online @nature.com! This has been work of nearly 10 years in collaboration with the National Institute of Genome Medicine 🇲🇽, the National Cancer Institute 🇲🇽, the @sangerinstitute.bsky.social and others ⬇️ www.nature.com/articles/s41...

Ancestry and somatic profile indicate acral melanoma origin and prognosis - Nature

Analysis of the somatic and transcriptomic profile of 123 acral melanoma samples from Mexican patients helps understand tumour origins and prognosis, and highlights the importance of including samples...

nature.com

Climate, Ecology, War & More: Dr. Glen Barry BigEarthData.ai@bigearthdata.ai · 7mo ago

Tumour-brain crosstalk restrains cancer immunity via a sensory-sympathetic axis ->Nature | More on "Brain tumor immune system interaction" at BigEarthData.ai

Tumour-brain crosstalk restrains cancer immunity via a sensory-sympathetic axis

KrasLSL−G12D/+; p53fl/fl (KP) mice have been described previously55. KP mice were crossed with Rosa26LSL−tdTomato mice to generate KP; LSL-tdTomato mice. Wild-type C57BL/6 J, Trpv1-cre, Rosa26LSL−DTR (LSL-DTR), Vglut2-cre, Baf53b-cre, Pparγfl/fl and CD11c-cre mice were purchased from The Jackson Laboratory. Trpv1-cre and...

nature.com

Waggoner Lab@labwaggoner.bsky.social · 9mo ago

@nature.com book review by @babiesresearch.bsky.social on book Hidden Guests Some of your cells are not genetically yours — what can they tell us about life and death? nature.com/articles/d41... greystonebooks.com/products/hid...

Some of your cells are not genetically yours — what can they tell us about life and death?

A tiny population of cells that are passed across the placenta between mother and baby challenge basic tenets of human immunology.

nature.com

Michela Locci@michelalocci.bsky.social · 9mo ago

I am excited to share that our work, in which we have dissected the signals driven by the nucleoside-modified mRNA and LNP components of mRNA vaccines that regulate germinal center (GC) responses, is now published in Cell! www.cell.com/cell/fulltex...

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

This study dissects the individual contributions of the different components of mRNA vaccines to immune responses. Nucleoside-modified mRNA promotes the production of type I interferons that act on de...

cell.com

Eugenio Contreras @eugecc.bsky.social · 9mo ago

Mind-blowing 🤯 IL-10⁺ Tregs restrain tumor growth?! Maybe it’s time to rethink “immunosuppressive cytokines” ; their function clearly depends on the inflammatory milieu. @mskcancercenter.bsky.social @cp-immunity.bsky.social www.cell.com/immunity/ful...

Opposing functions of distinct regulatory T cell subsets in colorectal cancer

Huang et al. study the heterogeneity of regulatory T (Treg) cells in a genetic model of colorectal cancer (CRC) and find that interleukin (IL)-10− Treg cells promote tumor progression, whereas IL-10+ ...

cell.com