🚨Faculty job search: University of Illinois Chicago Micro & Immuno department is hiring! Open rank and open area within host-pathogen interactions. Apply by May 31 to join us in UI College of Medicine in the heart of Chicago! uic.csod.com/ux/ats/caree...

The first instrument of the Peritore lab arrived today! Shout out to @cytiva.bsky.social for the matching AKTA lego 🫡🧫🦠🧪

The Peritore Lab officially opens its doors in 2026! I am seeking an organized, motivated technician to join our team focused on host-pathogen interaction research. For details on current research, check out: www.peritorelab.com Job listing: osu.wd1.myworkdayjobs.com/OSUCareers/j... #MicroSky

Peritore Lab | Microbial Infection & Immunity | Ohio State University Medical Center

Peritore Lab | Microbial Infection & Immunity | Ohio State University Medical Center

peritorelab.com

I love this thread by @glycoshape.org, this is @bsky.app at its best!

GlycoShape@glycoshape.org · 8mo ago

Super interesting work from @carolynbertozzi.bskyverified.social group about the effects of glycosylation in protein structure and function at the proteome scale 🤯💥🤩 Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵

We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect. The full study is now online at Cell. @cp-cell.bsky.social Paper 👉 www.cell.com/cell/fulltex... Thread for a synopsis 👉 bsky.app/profile/alex...

Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks

Psilocybin reshapes brain networks through activity-dependent plasticity, including a weakening of recurrent cortical loops that could underlie its therapeutic effects.

cell.com

Alex Kwan@alexkwan.bsky.social · 12mo ago

New preprint + thread 🧵 #Psychedelics induce the formation of new synapses, but where do they connect? Our rabies tracing study reveals that #psilocybin shifts connectivity across specific cortical networks. www.biorxiv.org/content/10.1... 1/12

“I’m tired of being constantly confronted by the consequences of my (in)actions.”

Join us in Colorado next spring for the Keystone Symposia “Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection”. Registrations are now open! Details below ⬇️

Joe Zackular@joeyzacks.bsky.social · 9mo ago

Registration is now open for @keystonesymposia.bsky.social "Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection." Deadline for scholarships and abstract selected short talks is Jan 7! Join us this May for an amazing meeting! keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26

🧪Thrilled to share our new study "The monoclonal antibody AZD5148 confers broad protection against TcdB-diverse Clostridioides difficile strains in mice” in PLoS Pathogens! @bordenlacy.bsky.social ➡️We show that this mAb alone protects against infection with strains encoding TcdB variants. 1/20

Excited to share our recent review in which @rcglover.bsky.social, @joeyzacks.bsky.social, @bordenlacy.bsky.social, and I discuss current advances in our understanding of immunity to C. difficile infection and what it will take to develop an effective vaccine 💉 www.sciencedirect.com/science/arti...

Immune Aspects of Clostridioides difficile Infection and Vaccine Development

sciencedirect.com

1/ Excited to share the first preprint from my lab! 🎉 My postdoc Paz asked how cholera toxin (CT) helps Vibrio cholerae thrive in the gut. Turns out, CT rewires epithelial metabolism toward L-lactate production—fueling pathogen growth in the small intestine during disease

Cholera toxin-induced disease generates epithelial cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine

Cholera toxin (CT) promotes Vibrio cholerae colonization by altering gut metabolism to favor pathogen growth. We have previously found that CT-induced disease leads to increased concentrations of L-la...

biorxiv.org

Imagine this: On the evening of March 8, you and your spouse unlock the door to your apartment building. As you step inside, two men—not in uniform—push their way in behind you. They tell you your visa has been revoked and that they are there to deport you.

In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report

National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

forbes.com

Preliminary injunction in nationwide indirect cost rate case. This means that the judge found that the plaintiffs (AAMC, et al.) are likely to win on the merits when the ruling is finalized. www.statnews.com/2025/03/05/n...

Judge issues preliminary injunction blocking Trump cuts to NIH research overhead payments

A federal judge issued a nationwide preliminary injunction blocking the Trump administration from slashing NIH payments for research overhead

statnews.com

A federal judge in Massachusetts today blocked an attempt by the National Institutes of Health to cut some $4 billion annually that goes to universities to cover the cost of supporting research on their campuses.

U.S. judge blocks NIH’s plan to slash overhead cost payments

Injunction allows universities to keep receiving billions to recover costs of supporting federal research on campus

scim.ag

This is Marco Rubio explaining how the USA promised to defend Ukraine forever if they got rid of their nuclear arsenal left after the Soviet Union fell. This is why lil marco was sinking into the couch. He was hoping we wouldn’t find it…so don’t RT right now this very second.

Everyone who ever got funding through NIAID should be aware of this bill and start sending messages to their US legislators. The bill intends to dissolve NIAID. This is Project 2025 www.congress.gov/bill/119th-c...

I created a brief spreadsheet of reductions I've heard of so far. Any additions you know of (especially if you have the links/receipts) would be great: docs.google.com/spreadsheets...

Graduate Reductions Across Biomedical Sciences (2025)

docs.google.com

🚨 WANT TO HELP US STAND UP FOR SCIENCE? 🚨 Here's a little update on where we're currently at with the planning process! Is your state red or grey & you want to see an event happen? Fill out our volunteer form or share with a friend! airtable.com/app4h5wUssMG... #standupforscience2025

🚨PA colleagues: "Senator Fetterman wants to hear from you about how the federal funding freeze is affecting Pennsylvania." "If your project has been impacted, please fill out our constituent impact form:" forms.office.com/g/mFv2JAPxpC Get out your Other Support and share that info!

PLOS has issued a statement on recent US Executive Orders and scientific integrity. We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry. plos.io/3D4O8cH

PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog

Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…

plos.io

Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at: 5calls.org

5 Calls

Spend 5 minutes. Make 5 calls. Make your voice heard.

5calls.org

Once again, these include a host of individual and institutional training grants that broaden participation in biomedical research: IMSD, MARC, U-RISE, G-RISE, Bridges to Doctorates, MOSAIC, etc. This strategy is nefarious and in direct conflict with the recent injunction against Trump anti-DEI EOs

Patrick Rothwell@perothwell.bsky.social · last yr.

More Friday night villainy: many NIH grant opportunities that disappeared two weeks ago and then reappeared last week have now disappeared again 🤬 Search grants.gov with close date in ascending order - 2 pages with closing dates now today (2/21/25), many with archive date tomorrow (2/22/25)

It’s been buried in all the news today, but every scientist in the US should pay attention to this: Mike Lauer went out on a limb for us all, sending out a memo saying institutes should start awarding grants. And it looks like Trump/Musk fired him for that. 🧪

Max Kozlov@maxkozlov.bsky.social · last yr.

NEW: In a further sign of turmoil at the NIH, Mike Lauer, who oversees the agency's $39 billion extramural budget that goes to research outside the NIH, has resigned effective tomorrow. This comes after top NIH official Larry Tabak abruptly retired yesterday.

CDC source: “We just had word that all our fellows and post doc staff are laid off effective immediately. The famous Epidemic Intelligence Service, aka the Disease Detectives, is no more. That’s 1260 staff. They are calling this ‘Phase 1’.”

This new Administration is a bunch of terrorists blowing up all that is meant to keep us safe and healthy. CDC cuts expected to devastate Epidemic Intelligence Service, a ‘crown jewel’ of public health www.statnews.com/2025/02/14/t... via @statnews.com

CDC cuts expected to devastate Epidemic Intelligence Service, a ‘crown jewel’ of public health

Members of the CDC's Epidemic Intelligence Service were warned Friday that many of them were about to be fired

statnews.com

Hi Vanderbilt, with your $545 million in NIH funding — how’s it going over there?

Philip Bump@pbump.com · last yr.

Where NIH funding went last year. s2.washingtonpost.com/camp-rw/?tra...

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

Executive wants to frame the NIH indirects cut as $4B in savings. But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.

@asm.org this better not be anticipatory obedience. I have 5 lab members planning on going to ASM microbe this year. I will absolutely pivot to another meeting if ASM gives in to anti-DEI efforts.

@vscooper.micropopbio.org and @mostlymicrobes.bsky.social while downloading scientist spotlights for teaching from the site; ASM has also scrubbed the entire IDEAA page including resources on LGBTQ+ scientists at asm.org/IDEAA/resources/pride-month