A drug originally developed for spinal cord injury may offer a fresh approach to treating #Alzheimers. In mouse studies, KCL-286 repaired dangerous DNA damage, reduced #Inflammation & targeted multiple disease-related pathways. @febsopenbio.bsky.social 👉 febs.onlinelibrary.wiley.com/doi/10.1002/...
FEBS Press
Repair of neuronal DNA damage in Alzheimer's disease by KCL-286. (A) Amyloid-β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double-strand breaks and glial activation. (B)....
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