Geert Carmeliet
@geertlab.bsky.social
cell metabolism of skeletal cells in bone development, metabolic disorders, bone metastasis and bone repair @KU Leuven. www.mebodd.com
Registration is now open for a free public bone health event at #ASBMR2026 in Boston. Hear directly from leading experts about healthy aging, menopause, exercise, osteoporosis prevention, and more. October 10 | John B. Hynes Convention Center | 5:00-6:00 p.m. ET meeting.asbmr.org/Program/Publ...
The Department of Food and Nutritional Sciences @uwmadison.bsky.social is hiring (Assistant, Associate, or Full Professor). Expertise in human nutrition, metabolism, aging, immune, or precision nutrition. PhD or MD, and RDN required. Closes August 30, 2026. Details and Apply at: go.wisc.edu/12v428
Tenured or Tenure Track Faculty in Food and Nutritional Sciences - Madison, Wisconsin, United States
Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:FacultyEmployment Type:Regula...
go.wisc.edu
ECTS 2026 in Girona is almost here! Mark your calendars for the European Calcified Tissue Society's premier meeting – April 24-27, 2026, in Girona, Spain. Download the ECTS Mobile App – browse the scientific programme, build your personalized itinerary - buff.ly/p8PjI50
The European Calcified Tissue Society is thrilled to announce the upcoming Clinical Training Course in Metabolic Bone Diseases, set to take place online from November 14 to 17, 2025, with on-demand access available until February 15, 2026. buff.ly/GJ9eS1d
"Being a scientist is not easy but it is an amazing job. With the new technology available there are so many questions you can answer, so much you can accomplish and contribute. Keep the dream." Congratulations Sylvia Christakos, Ph.D.!
🚨 Where does lipid peroxidation kick off in ferroptosis? 🔥Excited to reveal ER-mitochondria contacts as hotspots of the lipid peroxidation cascade! Kudos to our Maria Livia Sassano @mariamls.bsky.social 🙏 to our amazing collaborators #Ferroptosis#contactsites#ER#mitochondria# doi.org/10.1038/s415...
Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis - Nature Cell Biology
Sassano et al. identify endoplasmic reticulum–mitochondria contact sites as the intracellular location where phospholipid peroxidation first occurs to promote ferroptosis. Manipulating these contact s...
doi.org
www.nature.com/articles/s41...
Metabolic adaptations direct cell fate during tissue regeneration - Nature
Metabolic enzymes of the tricarboxylic acid cycle, such as 2-oxoglutarate dehydrogenase, are differentially expressed in absorptive and secretory lineages, guiding cell fate establishment and offering...
nature.com
New paper from our lab! In this study, we show that AML cells critically depend on LDHA to maintain their NAD+/NADH balance. Congrats to first author Ayşegül Erdem and all co-authors! cancerandmetabolism.biomedcentral.com/articles/10....
Lactate dehydrogenase A-coupled NAD+ regeneration is critical for acute myeloid leukemia cell survival - Cancer & Metabolism
Background Enhanced glycolysis plays a pivotal role in fueling the aberrant proliferation, survival and therapy resistance of acute myeloid leukemia (AML) cells. Here, we aimed to elucidate the extent...
cancerandmetabolism.biomedcentral.com
We have re-openend this position for a post-doctoral fellow in our lab! Reach out if you have an interest in studying metabolism in cancer/stem cells and ideally have some mass spec experience. Please share!
Nick van Gastel@nickvangastel.bsky.social · 2y agoWe are hiring! There is still time to apply for an open postdoc position in stem cell metabolomics (mass spec experience required) in our lab, and we’ll soon open applications for a PhD student interested in studying metabolic crosstalk in the bone marrow (but feel free to already send me your CV)!
I'm excited to share our latest story from the @lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/
Intracellular metabolic gradients dictate dependence on exogenous pyruvate
Nature Metabolism - Jackson et al. provide insight into how metabolic adaptations that accompany cell state transitions drive reliance on exogenous nutrient availability, focusing on pyruvate as a...
rdcu.be
www.nature.com/articles/s42... Metabolites are not genes. repeat, please!
Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics - Nature Metabolism
Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites compared with genes, pat...
nature.com
Early Registration Deadline for the congress in Innsbruck! REGISTER TO NOT MISS OUT Register until the 23 March to get the early registration fee and seize the opportunity to share science with colleagues from all around the world. www.ects2025.org/registration/
I feel extremely fortunate to have had the chance to learn from & work with Chuck Chan, building on some of his seminal discoveries and scientific vision. A truly 'chuckesque' manuscript by a wonderful collaborative & interdisciplinary team @cp-cellstemcell.bsky.social www.cell.com/cell-stem-ce...
Human skeletal development and regeneration are shaped by functional diversity of stem cells across skeletal sites
Ambrosi and colleagues profile human skeletal stem cells (hSSCs) across ten fetal skeletal sites and from patients throughout adulthood, identifying, mapping, and functionally testing four distinct hS...
cell.com
Thanks to all co-authors for excellent collaboration and thanks to @kuleuven.bsky.social and FWO for funding.
Nature Metabolism@natmetabolism.nature.com · last yr.RESEARCH | S Loopmans, @geertlab.bsky.social et al. (KU Leuven): The pentose phosphate pathway in #chondrocytes provides reducing power to ensure proteostasis necessary for #bone lengthening 🦴 🐁 https://bit.ly/3X1RuDS
Massive work from Jess Spinelli's lab at UMASS demonstrating a SECOND electron carrier in the mammalian ETC: www.cell.com/cell/fulltex...
Rhodoquinone carries electrons in the mammalian electron transport chain
Valeros et al. identify rhodoquinone (RQ), an electron carrier present in mammalian mitochondria, that can deliver electrons to fumarate instead of O2 as the terminal electron acceptor. The authors de...
cell.com
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis: Cell Metabolism www.cell.com/cell-metabol...
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis
Lactate elevations are a hallmark of human disease, but the mechanisms regulating lactate levels remain poorly understood. Here, Lee et al. elucidate the mechanisms of lactate homeostasis. These invol...
cell.com
very interesting research and great mentor!!
Nick van Gastel@nickvangastel.bsky.social · 2y agoWe are hiring at different levels! - Lab technician for mouse experiments - Postdoctoral fellow with experience in mass spectrometry-based metabolomics For more information: www.deduveinstitute.be/jobs & www.deduveinstitute.be/research-gro... Come join our team and contribute to exciting science!
Hi all, our lab will soon recruit a PhD student working within a very exciting MSCA Horizon Doctoral network working on ageing, UNION, which gathers some fantastic scientists. Please apply if your profile fits our project (see attached advert). Looking forward to working with you!
Big congratulations to Shauni Loopmans for her excellent PhD research, now online in @natmetabolism.bsky.social. This study reveals that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival rdcu.be/d5Q65 (1/3)
The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes
Nature Metabolism - Loopmans et al. show that the pentose phosphate pathway in chondrocytes provides reducing power to ensure proteostasis necessary for bone lengthening.
rdcu.be
⏰ Deadline is approaching (Feb 6!) to apply for scholarships + short talks for the Keystone meeting on metabolism in development! keysym.us/KSMetabDev25 The meeting is May 7-9 in Beverly, MA and will be a unique forum for discussing the role of metabolites in development. Hope to see you there!
Congratulations Ginevra with these very exciting findings!! and congratulations to the whole @fendtlab.bsky.social team!!
Ginevra Doglioni@ginevradoglioni.bsky.social · 2y agoBeyond excited to share that the main work of my PhD on how aspartate signaling drives metastasis is finally out in @nature.com ✨ -> go.nature.com/4gCYtuL A huge thank to the @fendtlab.bsky.social and all our collaborators for the terrific team work 🙏 A brief 🧵