Excited to share the latest preprint spearheaded by @ankitasharma.bsky.social We show that SP1 works with the #Wnt signalling pathway to drive cell growth in colon development and cancer. Cross-species analysis confirmed this role is conserved, suggesting potential for dual targeting in CRC therapy.
SP1 amplifies the effects of cellular proliferation via the Wnt/β-catenin pathway in colon development and cancer https://www.biorxiv.org/content/10.1101/2025.06.05.658012v1