Rui Gonçalo Martinho
@martinholab.bsky.social
Our AIM is to understand the way germ cells segregate from the soma and differentiate into functional gametes.
Any suggestion for a particularly good anti-H3K4me3 antibody for immunostaining in Drosophila? Lately we have been using AB8580 (rabbit) that works well (i need to double check the batch number), but it is a bit dirty (punctuated staining in cytoplasm). Thanks!!!!
“Part of what happens with a lot of this stuff is it's sort of like being too early to the party," says Gustavson. "Because of their [Eastman Kodak's] research labs and innovative nature, they tended to create things that, were ahead of the curve, not behind it." www.bbc.com/future/artic...
A 'toaster with a lens': The story behind the first handheld digital camera
In 1975, a young engineer in the company that made Kodak film took the first picture on a handheld digital camera. Photography would never be the same again.
bbc.com
Is there any Drosophila species known to naturally specify more than one oocyte per egg chamber? I’ve been looking through the literature but haven’t found any exceptions. Does an oddball species exist, or is the ‘one-oocyte-per-cyst’ rule truly universal across the genus?
C. elegans researchers were early adopters of open science: "The development of common resources and the belief that research findings and mutant strains should be freely shared has propelled worm research to the forefront" www.pnas.org/doi/10.1073/...
From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism | PNAS
Experimental organisms such as the nematode Caenorhabditis elegans are fundamental to biological discovery. The success of C. elegans research has ...
pnas.org
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social www.cell.com/cell/fulltex... If you want to know more, read the 🧵 below:
TT faculty job opening in #Neuroscience! We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply academicjobsonline.org/ajo/jobs/30961
Brandeis University, Biology Department
Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US
academicjobsonline.org
🪰 A new ‘Eyemap’ developed by a team led by Arthur Zhao & @michaelreiser.bsky.social reveals how visual information detected by the fly’s eye shows up in neurons deep in the brain. Remarkably, the eye’s shape determines how flies see motion.👁️ 🔗 hhmi.news/4kSZjou
Most migratory birds are gone but its still a gorgeous place do visit - Boquilobo Bog Natural Reserve.
Not today, parasitic #wasps!✋🚫 #Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵 This provides a physical defense against #parasitic wasp oviposition🛡️ www.science.org/doi/10.1126/...
Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n jobs.utoronto.ca/job/Toronto-... jobs.utoronto.ca/job/Toronto-...
Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...
#FossilFriday ‘Black Beauty’, one of the smallest-known specimens of Tyrannosaurus rex, displayed at The Royal Tyrell Museum in Calgary, Alberta. wp.me/p3ihHu-1MX
Quick Drosophila question: I’m planning to integrate a construct on the second chromosome but would like to avoid the attP40 landing site. Any suggestion for a good alternative attP site on chromosome II? It’s for a skeletal-muscle–related project. Thanks! 🙂 Rui
Our latest issue is out!👇 www.cell.com/current-biol... On the cover: Nautilus ≈ 🐙+🐚 (Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )
Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...
Epigenetic relay: Polycomb-directed DNA methylation in mammalian development
In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...
journals.plos.org
Chart from last year... No big change in % of US applicants, or? . marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...
📰 New paper alert! In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells. The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...
Vienna BioCenter@viennabiocenter.bsky.social · last yr.How cells lock down “jumping genes”: Researchers from IMBA and IMP identify the first protein interactions that trigger PIWI–piRNA–mediated transposon silencing, using AlphaFold predictions, genetics, biochemistry and cell biology. Read more: www.viennabiocenter.org/about/news/t...
Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪
www.biorxiv.org/content/10.1...
Rapid protamine evolution suppresses meiotic drive in Drosophila
Many animal species replace histones with protamines during spermatogenesis. Despite their importance for sperm function, protamines rapidly evolve in many species; the biological causes behind their ...
biorxiv.org
I hope everyone on the other side of the Earth is enjoying the total lunar eclipse! Except for flat Earthers.
Yesterday me and my lab celebrated #20years @mpi-cbg.de. There is a lot to say about that but the pictures from the event tell it better. Thanks city of #Dresden for the nice fireworks. That was unexpected. 10 more years or so? #LoPaTs 💕
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
🚨 New from our lab: Here we explored how aging contributes to harmful protein aggregation in diseases like Huntington’s & ALS. The culprit? An overlooked aging factor — EPS8 and RAC signaling. #Aging #Longevity #Proteostasis #ALSResearch 🧵 www.nature.com/articles/s43...
The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation - Nature Aging
Aging is a risk factor for neurodegenerative diseases associated with protein aggregation. Here the authors identify age-related hyperactivation of EPS8/RAC signaling in C. elegans as a driver of path...
nature.com
Private tour of the Louvre is a special treat. They were vacuuming the Sphinx. You may not have seen a Sphinx being brushed, so I am sharing.
Our new preprint is out ! We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles. Check it out and please share @igdrennes.bsky.social
flymuscles@flymuscles.bsky.social · last yr.I read the preprint. It's very beautiful work from Hadi Boukhatmi's group. They test how if at all #Drosophila can repair their #muscles. www.biorxiv.org/content/10.1...
The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1
Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....
