Niklaus Grunwald

@grunwald.bsky.social

Genomic epidemiology, population genomics, plant pathology, pathogen emergence, #Oomycetes, #Phytophthora, #SuddenOakDeath. Opinions are my own. 🧬🦠🧪🖥️

Heat-tree: Cross-Platform Software for Interactive and Embeddable Phylogenetic Tree Visualization and Editing doi.org/10.1094/PHYT...

Heat-tree: Cross-Platform Software for Interactive and Embeddable Phylogenetic Tree Visualization and Editing | PhytoFrontiers™

Phylogenetic trees are the primary framework for conveying evolutionary relationships. While many tools exist for visualizing phylogenetic trees, most are limited to static graphics, require coding expertise, or are developed for a specific website and not easily reusable or extensible. To address these limitations, we developed heat-tree, a collection of software packages in JavaScript, R, and Python for interactive visualization, manipulation, and editing of phylogenetic trees and their associated metadata. Heat-tree allows for the creation of customizable, web-compatible tree visualizations that can be easily embedded in R Markdown, Jupyter Notebooks, and Quarto documents, as well as directly in HTML/JavaScript applications and websites. The package supports radial and rectangular tree layouts, automated translation of metadata values into visual encodings on the tree, interactive tree editing, and export capabilities for publication-quality figures. All visualization parameters are definable programmatically or interactively using the comprehensive graphical user interface included with each visualization. Heat-tree was designed to be a user-friendly software package for interactive tree viewing, manipulation, editing, and self-contained, embeddable visualization across software environments.

doi.org

Our PathogenSurveillance pipeline is out in bioRxiv. PathogenSurveillance is an open-source and automated Nextflow pipeline for population genomic analyses of WGS data. It is flexible, using both short and long read data, mixed samples of prokaryotes and eukaryotes. www.biorxiv.org/content/10.1...

PathogenSurveillance: an automated pipeline for population genomic analyses and pathogen identification

Whole genome sequencing (WGS) offers a comprehensive, organism-agnostic method that effectively meets the need for efficient, reliable, and standardized responses to emerging threats from pathogens an...

biorxiv.org

Australia has one of the best and most rigorous approaches and we can all learn from your experience. I like the thought of strategies to build and maintain social license and trustworthiness before, and during any outbreak and the period of response.

Peter Solomon@plantpathpete.bsky.social · 10mo ago

great Niklaus and happy to chat more ... you can see some of what we're doing in this space at plantbiosecuritycentre.edu.au/projects/ ... there are a couple of social science projects in there now and about to advertise another.

Scientists are removing words like “diverse” and “disparities” from hundreds of federal grant renewals to avoid getting flagged in the Trump administration’s focus on eliminating diversity

ICYMI-- I did. A study of software developers found it took them 19% more time to do their work when they used AI tools. At the same time, they *perceived* they had saved time. They thought they would work faster and so they falsely "believed AI had sped them up by 20%."

Measuring the Impact of Early-2025 AI on Experienced Open-Source Developer Productivity

We conduct a randomized controlled trial to understand how early-2025 AI tools affect the productivity of experienced open-source developers working on their own repositories. Surprisingly, we find th...

metr.org