Join a great group in the vascbio field in beautiful Amsterdam!

Stephan Huveneers@huveneerslab.bsky.social · 2mo ago

We are hiring! Are you an ambitious postdoc with a background in vascular bioengineering and cell biology? Then please join our team at Amsterdam UMC and help unravel the mechanisms that govern vascular integrity. #embobuildnetworks #vascularbiology #EVBO werkenbij.amsterdamumc.org/en/vacatures...

Breakthroughs don’t happen by following the obvious path. They begin with people who dare to ask new questions. Who connect ideas others might not see. Who bring science, imagination and ambition together. At the NKI, these inspired minds move research forward. Where science meets inspired minds.

Will you be our next junior group leader? Check out how Natalie Scholes, Gordie Watt and @woutoosterheert.bsky.social experience starting their groups at the Netherlands Cancer Institute. Apply before August: www.nki.nl/news-events/... #Vacancy #JuniorPI #ResearchOpportunity #NKI #EarlyDetection

Read about how research into lymphatic function is changing our understanding of immune regulation in the lungs in our review: doi.org/10.1016/j.co... Congratulations to co-authors Amy Rivers and Camila Migues Ramirez!

Irena Roci et al. @petrovalab.bsky.social show that the water channel AQP1 sustains lymphatic endothelial cell migration under osmotic stress, establishing tissue #osmolarity as a key biophysical determinant of postnatal #lymphangiogenesis. rupress.org/jem/article/... #lymphatics #AQP1

Happy to share that our latest work on VEGFR2 in lymphatic endothelium is published @natcomms.nature.com “VEGFR2 is required for VEGF-C–VEGFR3–PI3Kα-mediated sprouting lymphangiogenesis” tinyurl.com/47bns9pp This project has been a long journey for the lab @taijamakinenlab.bsky.social , A thread.

I am looking for two postdocs to join our lab - One (bio)image analyst - One cell biologist interested to work on lymphatics! The positions will open soon, be in touch!

This beautiful work from the lab in Uppsala @taijamakinenlab.bs made it to the cover ! Happy to be part of it ! Congrats again to the first author Marle Kraft ! Stunning images

Nature Cardiovascular Research@natcardiovascres.nature.com · last yr.

❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more! www.nature.com/natcardiovas...

Extremely grateful to be granted a two year post-doctoral fellowship by @embo.org to study the earliest phases of mutant to malignant cell transition during breast cancer initiation using intravital microscopy. Thank to @vanrheenenlab.bsky.social for the immense support! @nkinl.bsky.social

An imbalance of Angiopoietin ligands & endothelial TIE2 hyperactivation underlies PI3KCA-driven #VenousMalformation👹 ⏫ #MuralCell Angpt1 ⏬ #EndothelialCell Angpt2 #SciArt @hansschoofs.bsky.social ‬@taijamakinenlab.bsky.social‬ @natcardiovascres.nature.com 2025 www.nature.com/articles/s44...

Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations. Read our work in ‪@natcardiovascres.nature.com by Marle Kraft et al. rdcu.be/enhST

Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations

Nature Cardiovascular Research - Kraft et al. identify TIE2 activation as a key driver of PIK3CA-related venous malformations and demonstrate that inhibiting TIE2 signaling can suppress the growth...

rdcu.be

📣New Preview out today @cp-devcell.bsky.social by Maria Azkanaz & Dimitrios Laskaris, describing the paper by Banjac et al @kimbakjensen.bsky.social lab! Stemness in flux: Dissecting intestinal crypt organization with multimodal approaches. Check it out here 👇 authors.elsevier.com/c/1l2MG5Sx5g...

• Happy to announce that our paper in @nature.com is finally out! Thanks to the perseverance of @taijamakinenlab.bsky.social and our many collaborators we finally pulled it off! A small 🧵 www.nature.com/articles/s41... Laymen video: www.nature.com/articles/d41...

Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium - Nature

Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from continuous...

nature.com

After 5 years my scientific chapter in Uppsala is coming to an end. Two weeks ago I have successfully defended my PhD thesis at the Mäkinenlab. Big thanks to Taija for being a true mentor and to Holger Gerhardt for acting as my opponent and critically assessing my work.