A friendly reminder that the 9th Austrian Cryo-EM (ACE) Symposium is taking place in Vienna, 24–25 September 2026. We'd love to see you there! Speakers: Chlanda, Costa, Demulder, Hurdiss, Su, Toropova, Weiss and Zhong. Abstract deadline 5 August; talks selected from submissions. shorturl.at/NGRZV

We're delighted to announce the 9th Austrian Cryo-EM (ACE) Symposium - Sept 24-25, 2026 at IMP, Vienna. Organized with @istaresearch.bsky.social 🎤 Abstract deadline: Aug 5, 2026 📅 Info & registration: imp.ac.at/research/cryo-em-symposium/

It was such a pleasure having @wulabharvard.bsky.social for the VBC seminar today in Vienna! Great structures and great presentation.

okay I spend some time testing Claude Fable from @anthropic.com and it is utterly useless in life science what ever I tried it almost instantaneously switched model. Even when looking test editing an email to a colleague. No paper editing, no script improvement no hypothesis sparring

📣 Registration is open for the 20th Microsymposium on RNA Biology! Join in at the Vienna BioCenter for three days of cutting-edge science, discussion & networking. 📅 17-19 June 2026 🧬 Poster abstract deadline: 19 May Info & registration: www.oeaw.ac.at/imba/seminar...

How do mitochondrial ribosomes keep pace with membrane insertion? Now out in NSMB: We show that mitoribosomes slow down at defined positions linked to membrane insertion and protein topology: rdcu.be/fhqIT #Mitochondria #Ribosome #CryoEM

Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed

Nature Structural & Molecular Biology - Schöndorf and Petrychenko et al. show that mitochondrial translation speed is coupled to OXA1L-mediated inner membrane insertion, with...

rdcu.be

A new paper in which we could contribute structural insights to the great biochemical work from our collaborators from UNC Chapel Hill. Sascha Amann from our lab was yet again able to solve several very challenging structures. This time of a SCF with Protac and target www.nature.com/articles/s41...

IMP@impvienna.bsky.social · 3mo ago

Cells have a built-in cleanup system to remove unwanted proteins, and scientists can hijack it to destroy cancer drivers. Now, researchers from our Haselbach lab and collaborators reveal how this works in near-atomic detail: https://www.nature.com/articles/s41467-026-72235-9

Happy to share my first adventure in #TeamTomo in collaboration with the talented @inaharasimov.bsky.social. It was a fun experience experience with a lot of learning along the way.

Carter Lab@carter-lab.bsky.social · 4mo ago

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

The @natsmb.nature.com March issue is out! Though always interested in proteostasis, in 2026 we have published and will continue to do so relevant content. Our editorial www.nature.com/articles/s41... recaps why the processes and mechanisms of proteostasis continue to interest us.

No stasis in proteostasis - Nature Structural & Molecular Biology

In this issue of Nature Structural & Molecular Biology, we focus on all things protein homeostasis, highlighting a variety of processes, from protein quality control in translation to autophagy.

nature.com

You asked, we listened. Millions of AI-predicted protein complex structures are now available in the #AlphaFold Database. This spans homodimers from 20 of the most studied species, including humans, as well as the World Health Organization’s priority pathogens list. www.ebi.ac.uk/about/news/t...

Learn more about the collaboration possibilities offered at Vienna BioCenter as Victoria Deneke shares her insights as a Postdoc at the Research Institute of Molecular Pathology. The VIP³ PostDoc Program call is open – apply now! training.vbc.ac.at/post-docs/vi... #VBCPostDoc

Our Spring call is now open with over 30+ fully funded positions in the life sciences. Want to know more? Join our Info Session on 26 March, 1600 (CET). Register now: www.vbcphd.at Institute of Molecular Biotechnology, Max Perutz Labs Vienna, IMP, Gregor Mendel Institute of Molecular Plant Biology

Welcome to the vbc and the wonderful Vienna cryo EM community

Manon Demulder@manondemulder.bsky.social · 5mo ago

Excited to announce I’m starting a new lab at @gmivienna.bsky.social (Vienna BioCentre) in Sept 2026 We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more Looking for people who want to build the lab together, get in touch! #teamtomo

Review from Fia B. Larsen in @rhp-lab.bsky.social with everything you always wanted to know about proteasomal control of transcription factors (but were afraid to ask about) Proteasomal control of transcription factors: mechanisms, regulation and dysregulation. doi.org/10.1007/s000...

A consortium of group leaders from IMP, IMBA (Vienna BioCenter) and ISTA has been awarded an FWF Emerging Fields grant to study how germ cells safeguard and pass on genetic information across generations.

#pictureofthemonth: March shows a “Cross-section” of the endoplasmic reticulum, a kind of membrane-labyrinth, using cryo-electron microscopy. More: www.biochem.mpg.de/plitzko March – Calendar of @mpiforbi.bsky.social and @mpibiochem.bsky.social 📸 Illustration by Jürgen Plitzko & Sven Klumpe

Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme? Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues. Apply by 16 MAR www.nature.com/naturecareer...

SAVE THE DATE: Ubiquitin & Friends Symposium 2026 on April 29-30 or even better, sign up now: lnkd.in/eEQmaCYT It takes place at Van Swieten Hall, 1090 Vienna & is organized by the SFB Targeted Protein Degradation (incl. numerous research groups at Vienna BioCenter) @sfb-tpd-vienna.bsky.social

We‘re looking for a motivated Master student to join our team! Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬 Then please apply! #optogenetics #metabolism #devbio #hESCs Please RT. Thank you!🙏

Institute of Molecular Biotechnology@imbavienna.bsky.social · 6mo ago

Apply to the Master’s project position at IMBA: https://www.oeaw.ac.at/imba/career-education/open-positions/pos2607-masters-project #research #jobs #europe #biology

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳 mrc.tal.net/vx/mobile-0/...

Our paper is out in @natcomms.nature.com! APOBEC3s drive mutagenesis in cancer. We uncover a novel pathway keeping them in check. The key is APOBEC3 binding of cellular RNAs, which simultaneously controls their nuclear localization and shields them from degradation. Read it here: rdcu.be/e4qaa

This is a video summarizing our recent paper (www.nature.com/articles/s41...) youtu.be/eNY2CRlYTRo

And a new paper from the lab. A follow up to a previous study in which we elucidate the mechanism of the nuclear transport. Read the full story: www.nature.com/articles/s41...

IMP@impvienna.bsky.social · 6mo ago

To regulate gene activity, proteasomes - waste disposal machines of cells - must enter the nucleus. IMP Researchers now show how the adaptor protein AKIRIN2 helps ferry this massive complex through the nuclear pore: https://www.nature.com/articles/s41467-026-69162-0

A near-complete map of human cytosolic degrons and their relevance for disease We measured degron potency of >200,000 30-residue tiles from >5,000 human proteins, and trained a model to predict degrons from sequence Led by @vvouts.bsky.social in @rhp-lab.bsky.social doi.org/10.1126/scia...

Great story from our neighbours at the university of Vienna. We are that we could contribute to this.

Max Perutz Labs Vienna@maxperutzlabs.ac.at · 6mo ago

Paper alert! 📢 How do cells fight viruses without harming themselves? 🧬 In @natcomms.nature.com, the @versteegga.bsky.social lab uncover a previously unknown safeguard that keeps DNA-mutating antiviral enzymes in check, protecting the genome while preserving antiviral defense ➡️ tinyurl.com/4xbxz9e8

Please share! My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th! uni-tuebingen.de/universitaet...

Check out our new paper in @natcomms.nature.com .com where we used #cryoEM together with biochemical and mutational analyses investigated the cotranslational protein folding by Ssb in yeast. Publication: doi.org/10.1038/s41467-025-67685-6 Check below for the cryoEM centric feed. 👇

Formation & function of #MembranelessOrganelles! #CryoET structures of #proteasome storage granules inside cells! Read our paper @cp-cell.bsky.social! ❕Publication: doi.org/10.1016/j.ce... ❕Press Release: www.biochem.mpg.de/en/pressroom @uoftmedicine.bsky.social @erc.europa.eu #UPSmeetMet

New work from our Haselbach lab with collaborators captures ribosomes 𝘮𝘪𝘥-𝘣𝘶𝘪𝘭𝘥 and reveals a flexible, modular strategy behind their assembly, rather than a strict assembly line. Published in _Nucleic Acids Research _👉 https://doi.org/10.1093/nar/gkag036