Fun at this year‘s Meyer lab outing with city rallye and barbeque at beautiful Gruga park. Now back to work!
Hemmo Meyer Lab
@hemmo-lab.bsky.social
Exploring the molecular biology of #ubiquitin and #VCPp97 -mediated stress responses in cells, #proteostasis, #lysophagy, #autophagy, #DNArepair. http://udue.de/qmTDR
What a great evening at this years' company run in Essen! 🏃♀️🏃♂️🎉 Several CRC 1430 groups, including @hemmo-lab.bsky.social and @icce-unidue.bsky.social, joined the race. Great teamwork, great spirit, and lots of fun—both on and off the course! 💙 #CRC1430 #TeamScience @unidue-zmb.bsky.social
Brilliant PhD thesis defense by Daniella Munro concluding a tour de force analysis of Ufd1-Npl4 substrates using induced-degradation. Watch out for her paper…
Our opinion article is out now on: Disentangling the response to lysosomal damage journals.biologists.com/jcs/article-... It discusses the concept of lysosome regeneration and the tools and reporters for diverse branches of the pathway. Great to work with coauthors Akiko and Shuhei.
Concluding an exciting and productive mini-research term with Bruno Antonny and the talented Thomas Chouly (Barelli Group) at Université Côte d‘Azur. Merci pour l’hospitalité et des discussions stimulantes.
Fantastic #autophagy meeting on the Oslo Fjord. Great talks and plenty of time and activities for discussion. Thanks to Anne, Ivan, Sharon and the other organizers for a great event.
ARCTiC: Autophagy Research Centre Targeting Cancer@arcticautophagy.bsky.social · 2mo agoExcited to welcome the autophagy community in Oslo for the International Autophagy Conference 2026. 📍 Holmen Fjordhotell, Oslo 📅 25–28 May 2026 Looking forward to outstanding science and discussions on the future of autophagy research. Thanks to our sponsors: @tandfonline @embojournal @NoAge100
Cdc48/p97 nibbling on #ubiquitin! Cool single molecule analysis study by the Tans group (with us) out now. rdcu.be/firGK
Great #ubfriends2026 meeting in Vienna. Presented our data on FAF1/2 mediated substrate loading onto VCP/p97. Fantastic talks, discussions and hospitality. Big thank you to the organizers! #ubiquitin
Excellent talk by our @unidue-zmb.bsky.social colleague Pinki Galhot from @hemmo-lab.bsky.social @imprs-lm.bsky.social 👏 #MK2026 @gbmev.bsky.social
Finally celebrating Matthi‘s paper publication on p97‘s accessory adapters. Great job. doi.org/10.1126/scia...
VCP/p97’s accessory adapters (FAF1, FAF2, UBXN7) boost unfolding and subsequent proteasomal degradation. #ubiquitin. Our paper is out now: Science Advances www.science.org/doi/10.1126/...
The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfolding
A group of accessory adapters positions the p97 adapter Ufd1 to boost substrate unfolding and subsequent proteasomal degradation.
science.org
Thrilled to be hosting Brenda Schulman, @aakritijain.bsky.social, @crismayorruiz.bsky.social @davidbalchin.bsky.social, @hemmo-lab.bsky.social, Ian Ganley, @kirsteinlab.bsky.social, Juliette Fedry, @elliottlab.bsky.social & @plantophagy.bsky.social - BIG THANKS for accepting the invitation 🙏
The Meyer lab Xmas dinner once again with traditional German skittle competition. We won! 🎳
Fantastic and productive meeting with the labs of Tamotsu Yoshimori, Shuhei Nakamura, Akiko Kuma at #Osaka University. Discussing perspectives of #microautophagy in th #lysosome regeneration after damage. Thanks so much for hosting me.
ATG9A assists lysosome membrane repair. Our preview on the Tooze lab’s paper is now online and free thru this link: authors.elsevier.com/a/1lzTz5Sx5g...
Excellent thesis defense by Pinki Gahlot concluding brillant work on a sensor module, SPG20-ITCH that detects lipid packing defects in the limiting membrane of permeabilized #lysosomes and initiates #lysophagy.
ATXN3-p97 facilitates #lysosomal restoration after damage by deubiquitinating LAMP2 and targeting it for degradation via microautophagy Hemmo Meyer and coworkers @hemmo-lab.bsky.social www.embopress.org/doi/full/10....
A successful @crc1430.bsky.social PhD Career Day is behind us! Thank you to all participants for the lively discussions and to our six guest speakers for their valuable insights. We enjoyed a day full of career advice, inspiring talks, and great networking over dinner. #PhDCareers #JobsAfterPhD
CRC 1430@crc1430.bsky.social · last yr.We’re excited for tomorrow’s @crc1430.bsky.social PhD Career Day! PhD students will explore career paths in and beyond academia — from an application workshop to talks and a panel with professionals. Looking forward to a day full of exchange, ideas, and networking! #FuturePhDs #PhDNetworking
Thank you again Chuna Choudhary from @choudharylabcpr.bsky.social at CPR in Copenhagen for visiting us last week for an exiting CRC1430 @crc1430.bsky.social seminar and for discussing the systems properties of ubiquitination www.cell.com/cell/fulltex...
We are looking for a PhD student with interest in protein biochemistry on a really cool project “Cooperation of deubiquitinating enzymes and VCP/p97 in cellular stress responses”. Build your own reactions! fully funded. apply with code 193-25. #ubiquitin
Concluding a productive @crc1430.bsky.social retreat with our PIs, exploring the 'Molecular Mechanisms of Cell State Transitions'. Thanks to everyone for the engaging discussions and collaborative efforts that made this retreat truly impactful! #ScienceInAction #ResearchCollaboration
Another excellent Frankfurt meeting #fcqc2025 on cellular quality control. Fantastic speaker lineup, discussions and hospitality. Thx to the organizers. #ubiquitin #autophagy fcqc.de
Great visit in Kiel Biochemistry with Elmar Wolf, Paul Saftig, M. Damme, M. Voß. Talking exciting (lysosome) science at the beautiful Kiel Fjord.
New VCP/p97 review article. Report on the excellent VCP meeting at CalTech last year and great overview on VCP and VCP disease. doi.org/10.1016/j.nb...
Different ways to target substrate proteins to the VCP/p97 unfolding machine: www.frontiersin.org/journals/mol...
