😃 In a new article published in J Biomech, Zero et al. show initial pre‑activation muscle length doesn’t significantly change the stretch–shortening cycle in permeabilized single fibres; non–cross‑bridge elements like titin were unlikely altered by starting length. 👀 buff.ly/eFwJbQe

Check out the new articles posted in our special issue, The Integrative Biology of Exercise, drawing on work in vertebrates and invertebrates to illustrate the plasticity or evolutionary changes necessary for exercise or sustained locomotion journals.biologists.com/jeb/issue/22...

#NoKings

We are hiring a POSTDOC on an NIH award to measure inertial effects of (in)active muscle. Please share and re-post widely! Please send expressions of interest to my UML email.

In honor of #BioVault, watch the full interview with Accelerated Muscle Biotechnologies as Anthony Hessel, PhD and Khoi Nguyen, PhD share benefits to muscle research, directions in x-ray diffraction, and more! Post: https://bit.ly/asi-amb-collab-840A-biovault 840A: https://bit.ly/840A-BioVault

👏Thank you for your service. There is nothing more direct then meeting with those with power of the purse. We all need to stay engaged with these people, letting them know how important the science infratructure and training pipelines are to the economic superiority of the States.

Karen Fleming@karenfleming.bsky.social · 6mo ago

First meeting is Rep Mfume’s office. #FundResearch #NIH #NSF @biophysicalsoc.bsky.social #BPS at the Capital advocating for #sciwnce #ResearchSavesLives @repkweisimfume.bsky.social

Aurora Scientific is proud to introduce our much-anticipated new product, built in partnership with @ambiotech.us: 840A BioVault! aurorascientific.com/products/mus... A portable chamber that takes your experiments from bench to beamline.

Ecstatic to see this launched! Thanks to our amazing partners @ambiotech.us, @hesselanthony.bsky.social and Khoi for their support throughout.

Aurora Scientific@aurorascientific.bsky.social · 7mo ago

Aurora Scientific is proud to introduce our much-anticipated new product, built in partnership with @ambiotech.us: 840A BioVault! aurorascientific.com/products/mus... A portable chamber that takes your experiments from bench to beamline.

Greenman et al. review the role of cMyBP-C post-translational modifications in health & disease. During cardiovascular disease, oxidative stress may drive the inverse relationship btwn. phosphorylation & S-glutathionylation of cMyBP-C, identifying new therapeutic targets rupress.org/jgp/article/...

We are proud to share that IMSI Co-Director Kiisa Nishikawa has been named the recipient of the 2026 SEB Bidder Lecture Award by the Society for Experimental Biology. Please join us in congratulating her on this outstanding achievement. #SEB2026 #ExperimentalBiology #ScientificAchievement #STEM

Our new project unveiling an integrative single-fiber framework that connect multi-omic cellular heterogeneity to molecular function in ICU-related muscle wasting! Congratulations to all authors especially Alexandra who led the whole project! Thank you to @lundbeckfonden.bsky.social for the support

There's exactly one normal man left on planet Earth.

Acyn@acyn.bsky.social · 8mo ago

Child at the podium: “A woo woo woo.” Mamdani: That’s how I felt when we came up with this plan. Together, we will expand the idea of what is possible in our city—and what sounds and noises we can make at a press conference.

A primer on the methods of skeletal and cardiac muscle mechanics using permeabilized preparations. New review from Anthony Hessel @hesselanthony.bsky.social, Christopher Rand @crand22.bsky.social, Khoi Nguyen and colleagues: rupress.org/jgp/article/... #Myofilaments #SkeletalMuscle #CardiacMuscle

New review from our partners Accelerated Muscle Biotechnologies (Anthony Hessel, PhD, Katelyn Manross, Khoi Nguyen), co-authored with our Chris Rand & Matthew Borkowski. #MusclePhysiology #CardiacResearch Check it out: https://bit.ly/a-primer-on-the-methods-of-skeletal-and-cardiac-muscle-mechanics

💪 NEW VIDEO: Flying over the A-band of an atomic-scale model of a vertebrate muscle sarcomere. Let's explore the molecular mechanics that make your muscles work. Rendered using @bradyajohnston.bsky.social 's molecular nodes Model based on the incredible work of the @raunser-lab.bsky.social lab

Accelerated Muscle Biotechnologies is looking for a subcontractor (muscle physiologist) for a 5 day project at Brookhaven National Laboratory, conducting muscle mechanics / small-angle X-ray diffraction experiments. See LinkedIn post for details. www.linkedin.com/posts/anthon...

Accelerated Muscle Biotechnologies is looking for a subcontractor (muscle physiologist) for a 5 day project at Brookhaven National Laboratory, conducting muscle mechanics / small-angle X-ray… | Anthon...

Accelerated Muscle Biotechnologies is looking for a subcontractor (muscle physiologist) for a 5 day project at Brookhaven National Laboratory, conducting muscle mechanics / small-angle X-ray diffracti...

linkedin.com

Really happy about this paper getting published, where we muse on some of the finer aspects of the permeablized fiber mechanics technique. Have things you wished were covered? Go write one of these up to! Science is better when we all share our "institutional knowledge"!

Journal of General Physiology@jgp.org · 8mo ago

Review: @hesselanthony.bsky.social @crand22.bsky.social, Nguyen et al. provide useful tips and tricks for all those beginning their journey into permeabilized muscle fiber mechanics. rupress.org/jgp/article/... #Myofilaments #SkeletalMuscle #CardiacMuscle

Anothee run at the P03 beamline PETRAIII complete. It was a exhausting run but we checked off all goals.

Americans are supposed to be the good guys. It makes applying/enforcing laws harder but that is the burden of being the good guys. We rarely reach that ideal in practice but I will do all I can to support those who fight the good fight to bring us towards it. Protests comes in many ways. #NoKings

The National Institutes of Health has agreed to settle lawsuits over its handling of grant applications that conflicted with President Donald Trump’s directives. https://scim.ag/4jsQ7sc

After legal deal, NIH to review grant proposals frozen, denied, or withdrawn because of Trump directives

Agreement requires agency to evaluate hundreds of applications “in good faith” using its standard process

scim.ag

Our team at Københavns Universitet - University of Copenhagen will soon be looking for a postdoc with experience in AI-driven vHTS and cardiac sarcomere modeling. If interested please send me an email. Spread the word :-)

First preprint from my PhD! www.biorxiv.org/content/10.1... We show that piperine: 1️⃣ increases ON myosin in resting skeletal muscle. 2️⃣ enhances dynamic contractility 3️⃣ in a muscle-type-dependent manner @hesselanthony.bsky.social

Piperine activates the thick filament of resting rat skeletal muscle, enhancing dynamic contractility in a fiber-type-dependent manner

Thick-filament activation, whereby myosin heads transition from an OFF to an ON state, is a key regulatory step in muscle contraction and a promising therapeutic target. The availability of ON-state m...

biorxiv.org

In February 2025, Aurora Scientific formed a strategic partnership with Accelerated Muscle Biotechnologies (AMB). Watch this video interview with Anthony Hessel, PhD and Khoi Nguyen, PhD from AMB, and our own Chris Rand to learn about our partnership! https://bit.ly/asi-amb-partnership-interview

New #PNASNews paper: Exercise suppresses DEAF1 to normalize mTORC1 activity and reverse muscle aging. #Myoblue tinyurl.com/y5rayxmz

Exercise suppresses DEAF1 to normalize mTORC1 activity and reverse muscle aging | PNAS

Skeletal muscle is essential for movement, respiration, and metabolism, with mTORC1 acting as a key regulator of protein synthesis and degradation....

tinyurl.com

Our collaborative effort unravelled puzzling results warranted more research on the topic of myosin and cardiac chamber specificities @ucph.bsky.social

Top recommendation for this post doc opportunity from my PhD lab group. Great mentor, lab, place to live. Amazing projects and an unusual amount of funding.

Kiisa Nishikawa@kiisa.bsky.social · 10mo ago

The Nishikawa lab at Northern Arizona University and the NSF-funded Integrative Movement Sciences Institute are hiring a postdoc to help develop multiscale muscle models - please apply and share widely! careers.nau.edu/cw/en-us/job...

How great is the HPV vaccine? It can even ⬇️ the risk of cervical cancer when given after precancerous cells are found. I wonder why RFK Jr isn't talking about this study.🤔 www.thelancet.com/journals/lan...

Early and long-term effects of prophylactic and post-excision human papillomavirus vaccination on recurrent high-grade cervical intraepithelial neoplasia relative to margin status: a retrospective coh...

Regardless of timing, HPV vaccination has a beneficial long-term effect in lowering the risk of CIN2+ recurrence. Despite the greater reduction in relapse achieved by post-excision vaccination, the di...

thelancet.com

Excited to share our preprint using time-resolved small-angle X-ray diffraction to study myosin motor conformations during isometric twitch and tetanus contractions in the slow-twitch rat soleus skeletal muscle #myoblue

bioRxiv Biophysics@biorxiv-biophys.bsky.social · 12mo ago

Distinct distributions of myosin motor conformations during contraction of slow and fast skeletal muscle https://www.biorxiv.org/content/10.1101/2025.10.13.679501v1

We are looking for an enthusiastic MD or PhD to work on a postdoc project on the molecular mechanisms underlying human hibernating myocardium and ischemic cardiomyopathy. If interested send me an email! #heart #cardiomyopathy #sarcomere

14 postdoctoral fellowships to the BRIDGE – Translational Excellence Programme

employment.ku.dk

Excited to share the first paper from my PhD! We looked at what traits help Aneides salamanders excel at climbing using museum specimens, CT scans, SEM, and more! No claws or toe pads, so how do they do it? In short, with long limbs, big feet and grippy toes! 🦎🧪 DM for PDF doi.org/10.1098/rspb...