🔥 Published today, and just in time for summer conferences, here are your guidelines for presenting badly www.nature.com/articles/s41... rdcu.be/fqa92
@hsiehyp.bsky.social
Are you a recent PhD graduate or postdoc? Are you looking for the next step in your career? Come check this out! sites.google.com/as.edu.tw/ip...
IPMB ECS
IPMB Early Career Symposium 2026 Open A New Chapter with IPMB
sites.google.com
What a nice summary of our preprint on cellular miniaturization! Thank you @anastasiamoraiti.bsky.social for writing this wonderful @prelights.bsky.social!
preLights@prelights.bsky.social · 3mo agoThe incredible shrinking cells: a guide to efficient downsizing @anastasiamoraiti.bsky.social highlights research from Ana Garoña & @marcofumasoni.bsky.social uncovering a putative mechanism for cell size evolution. #preprint #evolution #cellbio #preLight⤵️: prelights.biologists.com/highlights/e...
Bacterial immune proteins have repeatedly evolved to become parts of eukaryotic immunity. But how? Our new preprint uncovers a recent horizontal transfer event & shows how eukaryotes co-opted a toxic bacterial immune protein 🦠🧪🧵 1/
If you know a graduating undergraduate looking for the chance to spend 1-2 years in a lab before graduate school, we're hiring! Our lab explores morphogenesis, defining how the cell adhesion & cytoskeletal machinery work together to allow cells to change shape & move tarheels.live/peiferlab/ 1/n RT
Celebrating our lab manager Aida Flor de la Cruz, on her 30th anniversary of working at @fredhutch.org @basicsci.fredhutch.org Aida is absolutely amazing at everything she does, from art, pottery, baking to microscopy, therapy, & drosophila genetics. We’re very lucky to have her.
📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.
🤯
Vivek Mutalik@vivekmutalik.bsky.social · 4mo ago📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.
Magnesium depletion by Candida albicans unleashes two unusual modes of colistin resistance in Pseudomonas aeruginosa with different fitness costs. @hsiehyp.bsky.social, Robert Ernst lab, @ajaidandekar.bsky.social, my lab. journals.plos.org/plosbiology/... ipmb.sinica.edu.tw/en/activitie...
@hsiehyp.bsky.social and Ian O’Keefe’s recent paper presented as a “Research highlight” in Nature Reviews Microbiology www.nature.com/articles/s41...
Candida albicans steals magnesium and Pseudomonas aeruginosa unleashes resistance - Nature Reviews Microbiology
This study uncovers how Pseudomonas aeruginosa acquires colistin resistance in magnesium-depleted environments created by Candida albicans by accumulating unique mutations in the lipid A biosynthetic ...
nature.com
Hiring Alert: My lab(www.labofpie.org) is looking for BS/MS-level research assistants to study fungal-bacterial competition. Come join us if you are interested! ipmb.sinica.edu.tw/en/recruitme...
IPMB | 中央研究院植物暨微生物學研究所
ipmb.sinica.edu.tw
New paper 🔔 Collaboration @sullivan-lab.bsky.social Marissa Gittrich led the work Klebsiella phage biology has focused almost entirely on capsulated strains, but capsule loss is the #1 resistance mechanism under phage predation. We used a naturally acapsular host to reveal the receptor landscape
Rebecca is starting her lab as a UCSF Sandler fellow in August 2026; folks at #Dros26 interested in host-parasitoid interactions should try to catch her at the meeting to find out about available positions: www.tarnopollab.org/people
People — Tarnopol Lab
tarnopollab.org
Harmit Singh Malik@harmitmalik.bsky.social · 5mo agoRebecca Tarnopol @tarnopol.bsky.social receives the 2026 Larry Sandler award for best Drosophila PhD thesis
Our story on the evolution of colistin resistance is just out on @plosbiology.org (journals.plos.org/plosbiology/... Evolution doesn’t happen in isolation. We show that competing fungi can rewire the evolutionary trajectory of colistin resistance in P. aeruginosa. Great teamwork with the Ernst lab
Magnesium depletion by Candida albicans unleashes two unusual modes of colistin resistance in Pseudomonas aeruginosa with different fitness costs
Bacterial resistance to the vital last-resort antibiotic colistin is an increasing challenge. This study shows that magnesium sequestration by C. albicans enables P. aeruginosa to evolve much higher l...
journals.plos.org
Some of us know how sweet procrastination can be! If you feel the same, good news: The abstract deadline for the EMBO Workshop has been extended to March 19! Don’t miss the opportunity to present your work June 2–5 2026 in Oeiras, Portugal!
Marco Fumasoni@marcofumasoni.bsky.social · 8mo ago📢 Join us in sunny Lisbon 🇵🇹 2-5 June for the @embo.org workshop ☀️ “The rules of the game: biophysical & molecular principles in cellular evolution” Apply by March 1st! Please repost to help spread the word! meetings.embo.org/event/26-cel... #EMBORulesOfTheGame @gimmfoundation.bsky.social
In new research, Yu-Ying Phoebe Hsieh, Ian O’Keefe, Ajai Dandekar, Harmit Malik &co reveal how magnesium sequestration by C. albicans enables P. aeruginosa to evolve much higher levels of resistance to colistin (a last-resort #antibiotic). 🧪#MicroSky
Magnesium depletion by Candida albicans unleashes two unusual modes of colistin resistance in Pseudomonas aeruginosa with different fitness costs
Bacterial resistance to the vital last-resort antibiotic colistin is an increasing challenge. This study shows that magnesium sequestration by C. albicans enables P. aeruginosa to evolve much higher…
plos.io
Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!
New lab preprint! Andrew Frando, Bobby Parsek, and Graham Roberts describe how components of the quinolone quorum sensing circuit of P. aeruginosa interact in competition with another Gram-negative bacterium, S. maltophilia -- it's a three-component AND logic gate. www.biorxiv.org/content/10.6...
biorxiv.org
Every American needs to see this. Each of the people murdered by ICE had a place in their community, and those kidnapped and imprisoned also were people with lives that touched many others
Molly Ploofkins@mollyploofkins.bsky.social · 6mo agoAlex Pretti’s coworkers take a moment of silence this morning
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again. www.nature.com/immersive/d4...
Very clever
Zamin Iqbal@zaminiqbal.bsky.social · 8mo ago@peterfineran.bsky.social and colleagues develop Tn-seq for phages by leveraging anti-CRISPR (Acr) as a positive selectable marker in the presence of CRISPR-Cas counter-selection, and identify essential genes in phage from non model orgs www.biorxiv.org/content/10.6...
CDFD is elated to announce a Distinguished Lecture by Dr. @harmitmalik.bsky.social , a noted Evolutionary Biologist, who has been selected as the INSA Overseas Chair 2025 for Molecular and Cellular Biology. Do join us!
It’s officially happening folks! The Microbial Population Biology Gordon Research Conference is back in Andover, New Hampshire starting June 27th of 2027! See you there!! @wcratcliff.bsky.social @ksbakes.bsky.social @surtlab.bsky.social #microsky #mevosky
My first lead author paper is out with Ben Kerr and @alisonfeder.bsky.social! We found that making an antiviral too strong can sometimes make resistance easier to evolve. This has implications for how we design drugs, choose doses, and think about viral evolution in the face of treatment. (1/n)
Intracellular interactions shape antiviral resistance outcomes in poliovirus via eco-evolutionary feedback - Nature Ecology & Evolution
A model of intrahost poliovirus replication shows that, after several rounds of replication, pocapavir, a poliovirus capsid inhibitor, collapses viral density, preventing intracellular interactions th...
nature.com
“Transcriptional and metabolic modeling analyses of developing Aspergillus fumigatus biofilms reveal metabolic shifts required for biofilm maturation” #microsky
Transcriptional and metabolic modeling analyses of developing Aspergillus fumigatus biofilms reveal metabolic shifts required for biofilm maturation | mSphere
Aspergillus fumigatus is the most common etiological agent of a collection of diseases termed aspergillosis. Chronic and invasive manifestations of aspergillosis are highlighted by the development of biofilm-like structures on and in tissue. These biofilm structures are resistant to contemporary antifungal drugs, even for strains that are susceptible by standard antimicrobial susceptibility testing methods. Consequently, understanding the mechanisms by which A. fumigatus induces, develops, and maintains biofilms to evade antifungal therapies is expected to illuminate biofilm-specific therapeutic targets. Here, we identify genes involved in fungal fermentation and regulation of transcription as important mediators of A. fumigatus biofilm development.
journals.asm.org
Congratulations to Aida de la Cruz, lab manager in the @harmitmalik.bsky.social Lab, on receiving the Hutchison Award! The award, presented by @fredhutch.org SPAC and named for Dr. Nancy Hutchison, recognizes phenomenal mentorship. It also comes with an awesome personalized bobblehead.
