« Secondary-type acute myeloid leukemia is associated with a higher risk of invasive fungal infection during intensive induction therapy. a correlative study on the ALFA 0702 trial. » By Jean-Eudes Fahrner at #ASH2025
Institut de la Leucémie - Leukemia Institute Paris Saint-Louis
@institut-leucemie.bsky.social
« Where do immunotherapies stand in management of acute leukemia in adults ? » By Nicolas Boissel from @hopitalsaintlouis.bsky.social at @ash.hematology.org
« Does stringent cytoreduction improve survival in myeloproliferative chronic myelomonocytic leukemia? a correlative study on the dacota trial. » By Raphaël Itzykson from @hopitalsaintlouis.bsky.social at @ash.hematology.org
« Real-world patterns of treatment intensity and prognostic model performance in older AML: Insights from the french ALFA-PPP cohort » By Lin-Pierre Zhao
« Real life treatments and outcomes of older patients aged more than 60 years with FLT3-mutated acute myeloid leukemia: Report from the multicentric french observational ALFA-PPP study » by Thorsten Braun
Yesterday Mathilde Chanut presented a study of the french acute leukemia intergroup « Therapy-related core binding factor Acute Myeloid Leukemia » #ASH2025
Congrats Régis Peffault de Latour for this outsanding présentation on « First-in-human evaluation of IL2RG blockade in patients with severe aplastic anemia that is refractory to or relapsed on immunosuppressive therapy » @hopitalsaintlouis.bsky.social #ASH2025
I’ve just learned a wonderful news: I was awarded the #Prix Olga Sain from La #Ligue contre le #cancer. I am so grateful to colleagues, collaborators, mentors whose support made this possible. And to my incredible team #Passarolab, the driving force&the future of what we’ll accomplish together!
Happy to share our article in collaboration with @leeat-keren.bsky.social at Weizmann Institute of Science and @institut-leucemie.bsky.social A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology www.science.org/doi/10.1126/...
A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology
Multiplexed imaging of aGVHD GI biopsies revealed epithelial remodeling and alteration in immune composition, offering insight into disease pathology.
science.org
Kudos to all the authors and collaborators involved in this long effort over the years! @inem-necker.bsky.social @hopitalnecker.bsky.social @institut-leucemie.bsky.social
doi.org/10.1084/jem.... Great collaboration with the group of Robert Zeiser linking microbiota-derived metabolites and central nervous system GVHD
Gut microbiota–derived TMAVA is a modulator of acute CNS-GVHD
In this study, we report that microbiota depletion exacerbates acute graft-versus-host disease in the central nervous system, driven by microglial activati
doi.org
Wonderful discussion with @landau.bsky.social visiting us at @institut-leucemie.bsky.social @hopitalsaintlouis.bsky.social in sunny Paris to give an inspiring talk on cutting-edge single-cell technologies. Thank you so much Dan for stopping by and see you soon! @lobrylab.bsky.social
AML patient blasts exhibit polarization defects upon interaction with bone marrow stromal cells. www.embopress.org/doi/full/10.... Work by Manuel Thery @manuelthery.bsky.social @institut-leucemie.bsky.social and co-workers.
Biomedical Picture of the Day BPoD@bpodaily.bsky.social · last yr.Normal blood progenitors in the bone marrow polarise towards the stromal niche, but acute myeloid leukaemia (a form of BM cancer) cells do not 📷 @el-khansa.bsky.social et al @manuelthery.bsky.social Lab, @ @upcite.bsky.social in @emboreports.org ➡️ bpod.org.uk/archive/2025...
♥️ Vous souhaitez soutenir la lutte contre la leucémie ? Participez à notre premier concert exceptionnel le 18 septembre au Collège de France. Un dialogue en musique menée par l'académicien Erik Orsenna et interprété par la pianiste Claire-Marie le Guay : Apprendre, Comprendre, Guérir
@jeansoulier.bsky.social : Germline predisposition to myeloid malignancies at #EHA2025 📷 Lydie da Costa
Marie-Charlotte Villy : Myeloid neoplasms risks for germline DDX41 pathogenic variants carriers at #EHA2025
Congrats Lina Benajiba for this presentation about clonal selection and its consequence in MPN at #EHA2025
Congrats Elizabeth Macintyre for this great talk about the implementation of science in diagnostics #EHA2025
Our latest study about the polarization capacities of leukemic blasts was published today in #EMBOReports. www.embopress.org/doi/full/10.... @manuelthery.bsky.social @el-khansa.bsky.social LinaBenajiba @lobrylab.bsky.social
AML patient blasts exhibit polarization defects upon interaction with bone marrow stromal cells | EMBO reports
imageimageHSPCs polarize in contact with bone marrow stromal cells constituting their niche. This study analyses the polarity of hematopoietic cells from AML patients using artificial micro-niches and...
embopress.org
Lancement à @hopitalsaintlouis.bsky.social @ap-hp.bsky.social d’une unité unique d’hémato-génétique : une prise en charge intégrée des prédispositions génétiques aux leucémies pour mieux soigner, prévenir et comprendre. Une avancée portée par l'IHU @institut-leucemie.bsky.social bit.ly/4jqpBOh
Thank you for the great discussions and the invitation! Likely one of the best view from a research institute! In the beautiful Barcelona ! Looking forward to future collaborations!
Josep Carreras Leukaemia Research Institute@carrerasijc.bsky.social · last yr.This Friday, do not miss Dr Rouault-Pierre's Invited Lecture! 💬 "Metabolic intervention in Myelodysplastic Neoplasm; Endoplasmic Reticulum Stress governs a splicing programme in healthy and malignant cells" 🗓️ 23 May, 12pm CEST 📍IJC Auditorium Online at 👉 us06web.zoom.us/webinar/regi...
‼️Plus que fière de vous présenter l'affiche de la 4e édition de #SeptembreRouge, campagne de sensibilisation aux cancers du sang initiée par @vivreavecunenmp.bsky.social en partenariat avec LMC France, la SFH, l'EFS, Unicancer, AIHemato, FIM , EuroBloodNet, @institut-leucemie.bsky.social
🩸🩸 Honorée et ravie de vous annoncer que la Société Française d'Hématologie sera partenaire de la 4e édition de #SeptembreRouge, mois de sensibilisation aux cancers du sang. Merci Emmanuel Raffoux pour votre confiance ! @vivreavecunenmp.bsky.social @institut-leucemie.bsky.social
Great collaboration with Robert Zeiser @institut-leucemie.bsky.social @upcite.bsky.social @ap-hp.bsky.social @insermpresse.bsky.social Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey @springernature.com @BMT journal rdcu.be/ehWV5
Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey
Bone Marrow Transplantation - Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey
rdcu.be
Wonderful time with Paolo Gallipoli from the @qmbci.bsky.social visiting us at @institut-leucemie.bsky.social to give a very inspiring seminar on the role of fatty acid metabolism in leukemia. Thank you so much Paolo and see you soon!!! @lobrylab.bsky.social
Marie Sébert à la #SFH2025 : prédispositions génétiques aux hémopathies myeloides - l'apport de la sociologie
