4th Frontiers in Electron and Scanning Probe Microscopy for the Physical and Life Sciences

Advances in electron microscopy instrumentation and methods continue to drive progress in the physical and life sciences. The 4th edition of this conference will bring together researchers from physic...

go.nature.com

Associate or Senior Editor, Nature Communications (Structural Biology, Biochemistry, or Biophysics)

Job Title: Associate or Senior Editor Locations: Pune, Shanghai, Beijing Application Deadline: 31st July'26 About Springer Nature Springer Nature is one of the leading publishers of research in the wo...

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Ubiquitination of glycogen and metabolites in cells and tissues - Nature

Nature - Ubiquitination of glycogen and metabolites in cells and tissues

nature.com

PhD student or Postdoc (f/m/d)- Understanding and manipulating ubiquitin ligase specificities -

The research group Ubiquitin Signaling Specificity (Dr. Sonja Lorenz) invites applications for the position as PhD student or Postdoc (f/m/d) – Understanding and manipulating ubiquitin ligase specifi...

mpinat.mpg.de

International Day for the Elimination of Violence against Women | United Nations

The International Day for the Elimination of Violence against Women aims to create awareness of the fact that violence against women is a human rights violation that impedes progress in many areas, in...

un.org

Molecular basis of SIFI activity in the integrated stress response - Nature

Nature - Molecular basis of SIFI activity in the integrated stress response

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O-GlcNAcylation reduces proteome solubility and regulates the formation of biomolecular condensates in human cells - Nature Communications

O-GlcNAcylation can regulate protein properties and functions. Here, the authors systematically study its impacts on protein solubility and biocondensate formation. O-GlcNAc dramatically reduces prote...

nature.com

Associate or Senior Editor (Organic Chemistry), Nature Communications

Job Title: Associate or Senior Editor (Organic Chemistry), Nature Communications Organisation: Nature Portfolio Locations: Jersey City, London, New York, Philadelphia or Washington DC - hybrid working...

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Structural basis for the ubiquitin chain recognition of the human 26S proteasome

Proteasomal degradation is a fundamental process for all eukaryotic life. A protein destined for degradation is first tagged with a polyubiquitin chain, which is selected by the proteasome. Different ...

biorxiv.org

Enhanced sensitivity and scalability with a Chip-Tip workflow enables deep single-cell proteomics - Nature Methods

Chip-Tip is a label-free quantification-based single-cell proteomics workflow for deep single-cell proteomics, which identifies over 5,000 proteins and 40,000 peptides in single HeLa cells.

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ATG8ylation of vacuolar membrane protects plants against cell wall damage - Nature Plants

ATG8ylation of the tonoplast, triggered by cell wall damage, acts as a vital vacuolar quality control mechanism that safeguards vacuolar integrity and ensures cell survival under stress.

nature.com

C-terminal amides mark proteins for degradation via SCF–FBXO31 - Nature

SCF–FBXO31 scans proteins for C-terminal amidation and marks them for subsequent proteasomal degradation.

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iDIA-QC: AI-empowered data-independent acquisition mass spectrometry-based quality control - Nature Communications

LC-MS-based proteomics often relies on data-dependent acquisition (DDA) for quality control. Here, the authors demonstrate that data-independent acquisition (DIA) outperforms DDA in detecting subtle c...

nature.com

MPicker: visualizing and picking membrane proteins for cryo-electron tomography - Nature Communications

Visualization and picking of membrane proteins in cryoET tomogram is often challenging. Here, the authors developed a software MPicker based on membrane flattening to simplify the visualization, picki...

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E2–Ub-R74G strategy reveals E2-specific ubiquitin conjugation profiles in live cells - Nature Chemical Biology

Shen and Yin developed a technology named FUSEP to profile the E2-specific ubiquitome that makes use of a fusion between E2 and ubiquitin carrying a R74G point mutation, which leaves an LGGG remnant f...

nature.com