Thank you! Was fun presenting “What Does It Mean to See?” with Mike Erkkinen and Barbara Schildkrout at #ANPA @braincircuits.bsky.social @massgenbrigham.bsky.social

Dr. Psychialove (he/him)@psychialove.com · 6mo ago

I don’t post much during ANPA but the “seeing” block with Schildkrout, @isaiahneuro.bsky.social & Erkkinen was amazing and is inspiring my own creativity for some talks that I have been working on. Also always great to see Rick Rubin and freestyle rap referenced #ANPA www.nature.com/articles/sre...

Excited for the start of #ANPA meeting today in Providence - make sure to stop by Julian Kutsche's poster this evening on visual imagery and #aphantasia - @braincircuits.bsky.social

A recent @natneuro.nature.com paper analyzed lesion network mapping and raised concerns about the validity of the method. See below 👇 for our response. www.biorxiv.org/content/10.6...

Michael Fox@foxmdphd.bsky.social · 6mo ago

A recent paper in @natureportfolio.nature.com raised concerns about the lesion network mapping method. Our team of 16 coauthors analyzed >1000 lesions and 34 symptoms and found that "The methodological foundations of lesion network mapping remain sound" www.biorxiv.org/content/10.6...

www.newscientist.com/article/2516...

AIs can’t stop recommending nuclear strikes in war game simulations

Leading AIs from OpenAI, Anthropic and Google opted to use nuclear weapons in simulated war games in 95 per cent of cases

newscientist.com

Can a brain injury make someone lose their imagination? We describe rare cases of acquired aphantasia, people who lost the ability to visually imagine after a stroke or other brain injury. Now published in Cortex 🧠 @braincircuits.bsky.social www.sciencedirect.com/science/arti...

Lesions Causing Aphantasia are Connected to the Fusiform Imagery Node

The absence of visual mental imagery, called aphantasia, occurs congenitally in up to 3% of the general population, but the brain regions responsible …

sciencedirect.com

Large, real world cohort of patients (n=468) receiving amyloid target therapies in our center tracks amyloid-related edema and hemorrhage and identifies unique risk factors for ARIA including high-normal sodium and elevated diastolic blood pressure www.medrxiv.org/content/10.6...

Real-World Characterization of Amyloid-Related Imaging Abnormalities (ARIA) in Lecanemab Treatment at an Academic Health System

Background The benefits of amyloid-β monoclonal antibodies for Alzheimer’s disease are tempered by the risk of amyloid-related imaging abnormalities (ARIA). Detailed real-world characterization of ARI...

medrxiv.org

“More than 7,800 research grants terminated or frozen. Some 25,000 scientists and personnel gone from agencies that oversee research. Proposed budget cuts of 35% — amounting to US$32 billion.”

Nature@nature.com · 7mo ago

US science after a year of Trump A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce. go.nature.com/4jSm0ui

This Thursday at noon. Join us (over Zoom) for the MIT Consciousness Club. George Mashour (University of Michigan Medical School) - "Consciousness and the Dying Brain" sites.google.com/view/mit-con... #neuroscience

From a new @thelancet.com article today entitled "Health care in the USA: money has become the mission" www.thelancet.com/journals/lan...

Are connectome-based network mapping methods and the >200 papers that have used it invalid? New paper out in @NatureNeuro says YES. nature.com/articles/s41... I have concerns about this new paper's methods and conclusions, but am biased. What do others think?

Investigating the methodological foundation of lesion network mapping - Nature Neuroscience

The lesion network mapping method links diverse brain lesions to similar functional brain networks, reflecting general brain organization rather than disorder-specific circuits.

nature.com

Was fun presenting our work on network localization of aphantasia at #ASSC @assc28.bsky.social - I get pretty excited about #consciousness and visual mental imagery

Nice coverage of our recent paper: “White matter disconnection in acquired criminality” in @springernature.com by @cuanschutz.bsky.social news.cuanschutz.edu/news-stories...

Study Finds Link Between Brain Injury And Criminal Behavior

Study shows criminality is associated with damage to a key brain pathway involved in emotional control and judgment

news.cuanschutz.edu

What is common knowledge in your field, but shocks outsiders? There are almost no routine clinical applications of functional MRI for diagnosis and treatment in Neurology

Mike Feigin 🥯@mikefeigin.bsky.social · last yr.

What is common knowledge in your field, but shocks outsiders? Scientists and governments aren’t colluding to hide the cure for cancer.

Thrilled our ADHD network mapping work is now out in Annals of the Child Neurology Society, and honored to be featured on the cover! 🔗 Full article: onlinelibrary.wiley.com/doi/full/10.... @childneurosoc.bsky.social @bostonchildrens.bsky.social @simonwarfield.bsky.social @braincircuits.bsky.social

Coordinate Network Mapping of Focal Brain Volume Differences in ADHD Reveals Common Patterns That Lack Specificity: A Systematic Review

Objective Attention-deficit/hyperactivity disorder (ADHD) has been associated with decreased regional brain volume, yet no consistent localization has emerged across studies. This discrepancy has be...

onlinelibrary.wiley.com

Can a brain injury lead someone to commit a crime? Brain imaging is increasingly introduced as evidence in criminal trials but it remains unclear which structural injuries play a causal role in criminal behavior. @braincircuits.bsky.social @foxmdphd.bsky.social www.nature.com/articles/s41...

White matter disconnection in acquired criminality - Molecular Psychiatry

Molecular Psychiatry - White matter disconnection in acquired criminality

nature.com

How far we’ve come in the “imagery debate”!

Nadine Dijkstra@nadinedijkstra.bsky.social · last yr.

Interesting new lesion meta-analysis of aphantasia, in line with the importance of a specific region in the fusiform gyrus, previously identified by @alfredospagna.bsky.social et al, for visual mental imagery 🧠 www.medrxiv.org/content/10.1...

Interesting new lesion meta-analysis of aphantasia, in line with the importance of a specific region in the fusiform gyrus, previously identified by @alfredospagna.bsky.social et al, for visual mental imagery 🧠 www.medrxiv.org/content/10.1...

Visual Mental Imagery and Aphantasia Lesions Map onto a Convergent Brain Network

Background Visual mental imagery, the ability to volitionally form perceptual representations without corresponding external stimuli, allows reliving of past events, solving problems and imagining the...

medrxiv.org

Can brain injury cause the loss of visual imagination? We studied #aphantasia due to brain injury. Lesions were in many different regions but 100% were connected to the fusiform imagery node - a region active during visual mental imagery @braincircuits.bsky.social www.medrxiv.org/content/10.1...

New online! Implications of AD plasma and PET biomarker discordance

When the moment came, Harvard didn’t hedge or flinch—it stood up. A reminder that integrity isn’t complicated, it’s just rare.

This is high art

How does early life adversity impact white matter brain connections and subsequent cognitive abilities? Adversity was associated with lower white matter integrity and later difficulty with arithmetic & receptive language yet interpersonal resilience was protective. www.pnas.org/doi/epub/10....

Standing room only for 2 hour symposium on functional neurological disorder (#FND) at the #AAN2025 meeting - with a focus on functional seizures, post concussive syndrome / functional cognitive disorder & pathophysiology. #BarbaraDworetzky @mattburkemd.bsky.social

Was fun to do a podcast about our recent paper on creativity and brain disease with Dr Norman Swan @abcnewsbot.bsky.social @braincircuits.bsky.social @foxmdphd.bsky.social @harvardmed.bsky.social www.abc.net.au/listen/progr...

What brain damage tells us about creativity - ABC listen

Scientists have long been aware of a paradox of neurodegenerative disease – that as the brain deteriorates, in some patients creativity flourishes. Researchers have used imaging techniques to map cre...

abc.net.au

What is midrash? Interesting analysis by Ishay Rosen-Zvi @harvarddivinity.bsky.social on unique midrashic terminology (and apparently the Qumran folks thought there was a Sefer haBrit given to Abraham 📜)

Cool talk by Aaron Boes on clinical applications and cognitive prognosis from network neuroimaging @bostonchildrens.bsky.social @harvardmed.bsky.social

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications

Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.

nature.com

99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...

Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry

This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.

jamanetwork.com

Measles top Page One. @usatoday.com

Does human creativity map to a specific brain circuit? Can damage to this brain circuit increase creativity? New paper by Julian Kutsche @isaiahneuro.bsky.social @braincircuits.bsky.social out today in JAMA Network says answer to both is YES. Paper is open access and great thread below:

Isaiah Kletenik@isaiahneuro.bsky.social · 2y ago

How can a brain disease increase creativity? We derive a brain circuit from creative tasks demonstrating they share reduced activity in the right frontal pole. Then we show that brain lesions & neurodegeneration that increase creativity are connected to this location jamanetwork.com/journals/jam...