#CancerImmuno Announcement📢 📅Final deadline closing this week (Thursday 16th April 2026, Midnight BST!) Register now & join us at the conference! we look forward to welcoming you to Portugal soon!🌞 Click here to register: bit.ly/4tKJVQ5
James Reading
@jamesreading.bsky.social
Immunologist | Assoc. Prof at UCL | Using T Cells to Track & Target Tumourigenesis | Cancer Interception | Immune Prevention | https://www.ucl.ac.uk/medical-sciences/divisions/cancer/our-research/pre-cancer-immunology
Please help spread the word by sharing the above post: @delgoffelab.bsky.social @thelundlab.bsky.social @tcellogic.bsky.social @elhamazizi.bsky.social @bergerslab.bsky.social @jguerriero.bsky.social @iannaconelab.bsky.social @luglilab.bsky.social @obenaufa.bsky.social @jamesreading.bsky.social
🚨 PhD Position available in our lab 🚨 exploring the power of blood immune multi-omics to detect lung cancer years prior to clinical diagnosis in a unique cohort of >10,000 CT screened individuals. ✅ Wet & dry lab ✅ September 2025 enrolment ✅ UK tuition fees only www.ucl.ac.uk/medical-scie...
Pre-Cancer Immunology
The Pre-Cancer Immunology Lab (James Reading Lab) is mapping pre-invasive T cell dynamics during carcinogenesis to detect and intercept cancer development.
ucl.ac.uk
🚨 Final day to send in your application to join @giampazolias.bsky.social & the Cancer Immunosurveillance group @cruk-mi.bsky.social. Don’t miss this great opportunity! @mcrcnews.bsky.social
Cancer Research UK Manchester Institute@cruk-mi.bsky.social · last yr.We are recruiting #postdoctoral scientists to join @giampazolias.bsky.social and our Cancer Immunosurveillance group 🧪🥼🧫🦠 For full details of the position, please visit our website: www.cruk.manchester.ac.uk/career/mi-24... Closing date: 4th April #OncoSky #CanSky #CancerResearch #microbiome
Nature research paper: Clonal driver neoantigen loss under EGFR TKI and immune selection pressures https://go.nature.com/4k6SCQD
Clonal driver neoantigen loss under EGFR TKI and immune selection pressures - Nature
We show the evolution of a case of EGFR mutant lung cancer treated with a combination of erlotinib, osimertinib, radiotherapy and a personalized neopeptide vaccine targeting somatic mutations, including EGFR exon 19 deletion.
go.nature.com
Interested in investigating the principles that regulate the establishment of tumour environments that promote or inhibit the anti-tumour function of the immune system? Our group is currently recruiting a postdoctoral fellow. Learn more about our research 👇 www.cruk.manchester.ac.uk/research-gro...
MI/25/01 – Postdoctoral Scientist – Cancer Inflammation And Immunity Group | Cancer Research UK Manchester Institute
cruk.manchester.ac.uk
#hiring #postdoc We are looking for a postdoc to work on anti-tumor gamma delta T cells in breast cancer metastasis mouse models. Apply here: www.gla.ac.uk/explore/jobs...
University of Glasgow - Explore - Jobs at Glasgow - Appointments - Research Associate (Breast Cancer Now) [164192]Search iconClose menu iconMenu icon bar 1Menu icon bar 2Menu icon bar 3
gla.ac.uk
How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3) doi.org/10.1038/s415...
Analysis of multi-condition single-cell data with latent embedding multivariate regression - Nature Genetics
Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...
doi.org
Interesting work, it's becoming clear that @santiagozelenay.bsky.social's 2015 work on the COX-PGE axis' role in tumor immune evasion is robust (and also that we really need to focus on type I IFN in anti-tumor immunity). #Immunology #Immunotherapy #Immunosky
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
Cyclooxygenase-driven prostaglandin E2, produced by a variety of tumors, drives malignant growth through successful evasion of type I interferon and/or T-cell-dependent tumor elimination. A remarkable synergy between cyclooxygenase inhibitors and checkpoint blockade immunotherapy results in tumor eradication.
cell.com
Anna Obenauf@obenaufa.bsky.social · 2y agoThrilled to share that our paper www.nature.com/articles/s41... is featured in a fantastic Nature News & Views piece by thomastueting.bsky.social! 🎉 Grateful for the spotlight on our research and its impact on understanding cancer immunology. www.nature.com/articles/d41... 👀👉 rdcu.be/d3cRz
A very rare position for an immunology professorship at Cambridge. Something to think about! www.jobs.cam.ac.uk/job/49381/
Associate Professor/Professor of Infection and/or Immunity - Job Opportunities - University of Cambridge
Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.
jobs.cam.ac.uk
This week in #Science #Immunology: Jan Petersen, Jamie Rossjohn, & colleagues have solved the #CrystalStructure of human #LAG3 – #HLADR1 – #peptide complex, a major target of #ImmuneCheckpoint #therapy!
Crystal structure of the human LAG-3–HLA-DR1–peptide complex
The structural basis of how the immune checkpoint molecule LAG-3 binds peptide HLA-II is resolved.
science.org
What a sensational line up!
The Lund Lab@thelundlab.bsky.social · 2y agoWe have a great line up and we are super excited by all the abstracts we have recieved! Register by Dec. 12 (11:59pm MST) to save $200 USD & access 2 meetings for the price of one! Join us in Vancouver in Feb. for the T Cell Differentiation in Tissue Microenvironments Keystone. hubs.la/Q02ZKxQV0
🚀 Advancing T-cell receptor (TCR) research! We developed tcrBLOSUM, a specialized substitution matrix for sensitive alignment of distant epitope-specific TCRs. Find out how our findings expand TCR analysis: doi.org/10.1093/bib/... #Bioinformatics #Immunology #AIRR with @pmeysman.bsky.social
tcrBLOSUM: an amino acid substitution matrix for sensitive alignment of distant epitope-specific TCRs
Abstract. Deciphering the specificity of T-cell receptor (TCR) repertoires is crucial for monitoring adaptive immune responses and developing targeted immu
doi.org
Every exemplar, case and occurrence needn't be a vignette
Wonderful work @barralab.bsky.social on the role of NKT cells in gut epithelial cell homeostasis. Huge congrats to Patricia, the team and @martalebrusant.bsky.social a rising unconventional T cell superstar that we are lucky to have slaying it in our lab!
Barral Lab@barrallab.bsky.social · 2y agoOur first 🦋 post! Very happy to share our latest paper just out in Cell Reports, exploring the crosstalk between immune and epithelial cells in the gut. Check it out! @vivianlilab.bsky.social @kingscollegelondon.bsky.social www.cell.com/cell-reports...
Our first 🦋 post! Very happy to share our latest paper just out in Cell Reports, exploring the crosstalk between immune and epithelial cells in the gut. Check it out! @vivianlilab.bsky.social @kingscollegelondon.bsky.social www.cell.com/cell-reports...
IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells
The crosstalk between immune and epithelial cells is vital to maintain intestinal homeostasis. Lebrusant-Fernandez et al. identify NKT cells in the small intestine as key regulators of epithelial biol...
cell.com
Totally agree. The immune system is an excellent biosensor and recorder of past experiences. UPenn Immune Health www.med.upenn.edu/immunehealth/ together with our Colton Autoimmunity Consortium www.coltonconsortium.org is profiling Immune Health of 1000's of subjects. Many ways to work towards a GIO
Immune Health Project | Immune Health | Perelman School of Medicine at the University of Pennsylvania
We are delighted to introduce the establishment of the Institute for Immunology & Immune Health (I3H), a reorganization of the Institute for Immunology (IFI) and Immune Health, led by E. John Wherry, PhD and Allie Greenplate, PhD.
med.upenn.edu
Michael Mina MD,PhD@michaelmina.bsky.social · 2y agoWe should of course also be developing immunological approaches to study exposures - which are considerably better for understanding pathogen spread and incidence than direct virus tests. Our immune memories hold immense information on exposures! elifesciences.org/articles/589... 15/