I spend most of my time doing very basic research, but I am at a symposium to honor Dan Kastner whom I’ve had the opportunity to collaborate with a couple times. It is jarring to see actual patients with diseases my lab helped model in zebrafish and makes me a little proud we could help.

The latest digest from the National Bureau of Economic Research

Our paper just appeared online @eLife: Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation doi.org/10.7554/eLif...

Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation

Immunoglobulin M has other functions beyond antibody class switching that have implications in asthma treatment.

doi.org

🎉 Excited to share our new preprint presenting a complete de novo assembly of the zebrafish genome; a major advance for zebrafish genomics and research! 🧬 Full paper: www.biorxiv.org/content/10.1... @zebrafishrock.bsky.social @izfs.bsky.social @zfinmod.bsky.social @modelzebrafish.bsky.social

Wow indeed. This is a disaster for U.S. science in so many ways. We're losing the future.

jon ben-menachem@jbenmenachem.com · 10mo ago

Wow. Harvard nuking its PhD programs - Science PhD admissions reduced by more than 75% - Arts & Humanities reduced by about 60% - Social Sciences by 50–70% - History by 60% - Biology by 75% - The German department will lose all PhD seats - Sociology from six PhD students to zero

Have you heard of the Zebrafish Rock! Slack Pro tankspace? Sponsored by ZFIN, it acts as the premier source for questions and queries for the #zebrafish community and beyond! If you are keen to join, please fill out this Google form at our website: linktr.ee/zebrafishrock

🚨 New #zebrafish reference genomes released! Both TU & AB assemblies now include long-missing regions; centromeres, telomeres, and segmental duplications (SDs). A major step toward complete, accurate models for functional & comparative genomics. 🧬🐟 #Genomics #T2T #Zebrafish

Exciting new #genomics resource! A high‑quality, chromosome‑level genome assembly of the garden slug (Deroceras laeve) is now available. academic.oup.com/g3journal/ad...

Out in Nature from @glennislogsdon.bsky.social. Amazing work on human centromeres and their evolution! www.nature.com/articles/s41...

The variation and evolution of complete human centromeres - Nature

A comparison of two complete sets of human centromeres reveals that the centromeres show at least a 4.1-fold increase in single-nucleotide variation compared with their unique flanks, and up to 3-fold...

nature.com

We are looking for a new director of the NIH Intramural Sequencing Center! Please spread the word: www.genome.gov/careers-trai...

Director, NIH Intramural Sequencing Center

NHGRI seeks to identify an outstanding Director to lead its NIH Intramural Sequencing Center (NISC) within its Division of Intramural Research (DIR).

genome.gov

We are excited to release several new GIAB products in advance of #ASHG23, including v1.0 TR and X&Y benchmarks, corrected GRCh38 reference, stratifications for T2T-CHM13, RNA-seq, GIAB tumor/normal data, and a v1.0 T2T-HG002 assembly with #T2T. Details at www.nist.gov/programs-pro...

Gotta admit that a day 2 zebrafish embryo is a lot cuter than a day 2 mouse embryo 🐠🧪🔬