Jayati Sharma, PhD, ScM

@jayatirsharma.bsky.social

📊 epidemiologist 🧬 genetics, envt, & public health in diverse pops 💻 postdoc @ NCI 📚✅ phd JHU Genetic Epi 📝 editor @genebites.org | AAAS MMF alum pronounced “JAY-uh-tea” all views my own

Working on this project was so fun! ❤️ It's really awesome to work with so many passionate scientists who are all committed to improving our field (despite a climate that might not always be so friendly to that) We'd love any feedback, especially from other trainees and early career researchers!

Roshni Patel@roshnipatel.bsky.social · 4w ago

So excited to see this out! It was an absolute joy and honor to work so closely w @jayatirsharma.bsky.social and @christacaggiano.bsky.social on this - both are terrific examples of the kind of interdisciplinary human genetics researchers that we need more of (and will be on the job market soon 👀)

I think this work really underscores that we are at a turning point in human genetics. There is a growing consensus that doing good research in human genetics requires an expanded skillset (including, e.g., one that can navigate the relationship between genetics, ancestry, and pop descriptors) (1/)

Jayati Sharma, PhD, ScM@jayatirsharma.bsky.social · 4w ago

In what has been a labor of love & joyful collaboration, we are super excited to share our preprint on recommendations towards the ethical and accurate use of population descriptors generated from a survey by trainees, for trainees. www.biorxiv.org/content/10.6...

NIH All of Us has just released a massive multi-omics dataset, including: • 535K WGS (120K+ added; now larger than UKB) • ~10K proteomics + RNAseq + long-read • ML-curated clinical notes • 68K with Fitbit data Kudos to this great initiative and to the participants for advancing science

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"The biases do not disappear; they get encoded into the model and then laundered into outputs that feel objective because they are numerical. Replacing one prestige filter with another that is harder to see or challenge is not progress toward equity in science; it’s the opposite.” 💯🧪

Ran Blekhman@blekhman.bsky.social · last mo.

I wanted to like QED's new 1% preprint ranking. I really did. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review. open.substack.com/pub/blekhman...

I miss Twitter, mostly because the conversation there for a brief period was so wide-ranging, could be non-hierarchical and forced me to consider view points different than mine. now all of that is splintered between Twitter, Bluesky and threads (😭😭), which feels like a real loss.

someday far in the future we will tell children of the mystical Google dot com of decades past: a place where we could ask a question and be directed to at least several dozen factual and valuable* answers written by other real people with actual experience

I just repeated the analysis for grants in fiscal year 2026. I found 98 grants with title changes upon administrative (non-competitive) renewal. Here is the removed word cloud for fiscal year 2026. 4/5

A word cloud of words removed from NIH grant titles in fiscal year 2026. The most commonly removed words are "equity", "diverse", "disparate", "racial", "gender, and similar terms.

🎉New preprint: Phenome-derived polygenic scores and social determinants jointly shape context-dependent disease risk. We evaluate disease risk along 2 complementary axes: • how genetic liability is represented • the social context in which it is expressed

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medRxivpreprint@medrxivpreprint.bsky.social · 4mo ago

Phenome-derived polygenic scores and social determinants jointly shape context-dependent disease risk https://www.medrxiv.org/content/10.64898/2026.04.16.26351039v1

@statnews.com conducted a national survey of NIH-funded researchers and found that, a year after Trump's return, many scientists are reeling, with some closing labs entirely. ‘This is like the Titanic,' one respondent told me. For full details, see our special report www.statnews.com/2026/03/19/n...

National survey of NIH-funded researchers shows precarious state of U.S. science — ‘This is like the Titanic’

A nationwide STAT survey of NIH-funded researchers reveals that, a year after Donald Trump's return to the White House, many scientists are reeling

statnews.com

Finger on the pulse: “Embedding communication and policy fluency into STEM training is not about adding polish. It is about responsibility. Students should graduate knowing not only how to generate knowledge, but how to explain it, contextualize it, and respond when it is misunderstood or misused.”👏

jp flores (he/him)@jpflores.rbind.io · 5mo ago

Check out my new piece in @sciencepolitics.bsky.social ! “We’re Training Scientists for a World That No Longer Exists” sciencepolitics.org/2026/03/18/w...

Despite *gestures broadly*, one bright light for me has been reading and editing so many wonderful pieces from our team at GeneBites on our corner of the internet, like this great one from @jpflores.rbind.io 🐭👇🏼

GeneBites@genebites.org · 6mo ago

Who says mice 🐁 can’t menstruate? Senior Editor @jpflores.rbind.io discusses a preprint study where scientists genetically engineered mice for menstrual-like bleeding to study the uterus’s rebuilding. That’s innovative, period. #genetics #scicomm Check it out here: genebites.org/2026/01/29/r...

🚨 Requesting help: I am looking for an agent who can facilitate more speaking gigs, podcast appearances, and interviews with journalists I want to more widely share my story and expertise as a trans geneticist who understands the reality and complexity of "biological sex" 🏳️‍⚧️🧬 Please signal boost?