"new ways to circumvent the will of Congress and starve American science" www.science.org/doi/10.1126/... @science.org @holdenthorp.bsky.social

Another red alert for American science

Although research has bipartisan support in the US Congress, and trust in science is above 75% across the country, the Trump administration seems as determined as ever to mortally wound the nation’s s...

science.org

Emerald from Rancho Bernardo needed help with a delayed grant that threatened layoffs at UCSD’s Biodynamics Lab. My staff worked with Emerald and the NIH to determine the cause of the grant’s delay and within a month, the lab received their full grant funding!

Every $1B cut to NIH = ~8 fewer approved drugs over a decade. Proposed $18B NIH cuts = risk of 144 fewer treatments reaching patients. The #geroscience pipeline is in the line of fire. www.brookings.edu/articles/the... #NIH #AgingResearch #ResearchFunding

Now hiring in NYC: Senior Director of Research Programs at The Jackson Laboratory. Define and drive the strategic vision for the research programs portfolio, lead project teams and partner with industry to advance translational models: https://go.jax.org/08aetr 🧪 💼

Senior Director, Research Programs

The Senior Director of Research Programs is responsible for the project management team and for overseeing project monitoring, reporting, and delivery in alignment with research strategy goals and tactics. The role provides strategic guidance to senior ...

go.jax.org

This is a story about life extension for dogs, in which my own pup makes several appearances www.theatlantic.com/science/2026...

Your Next Dog May Live Longer

A new pill could soon extend dogs’ lives. How will that change our relationship with our pets?

theatlantic.com

Christin Glorioso writes about BioAge Labs' NLRP3 inhibitor which cleared a Phase 1 clinical trial: drglorioso.substack.com/p/bioages-lo...

BioAge’s Longevity Drug Cleared Phase 1 with an 86% Drop in Inflammation

Inflammaging, CRP, and the longevity drugs coming to reduce them

drglorioso.substack.com

Read up about the course ARPA-H programs take from beginning to end: arpa-h.gov/news-and-eve...

ARPA-H 101: The lifecycle of an ARPA-H program

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research ranging in scale from molecular to societal to deliver health breakthroughs in years, not decades.

arpa-h.gov

Biomarkers of Aging Consortium has started uploading recordings from the Oct. 2025 conference: www.youtube.com/@Biomarkerso...

Biomarkers of Aging Consortium

Establishing Reliable Biomarkers of Aging for Longevity Interventions.

youtube.com

Registration is now open for the 2026 JAX–NYSCF Conference. 🧬 Marking the anniversary of iPSC discovery, this year’s meeting brings together global leaders in stem cell science to share breakthroughs and shape what’s next in translational research. Join us: https://go.jax.org/jax-nyscf-conf

ARPA-H has announced a new program that aims to detect, understand the health impacts of, and remove microplastics from the body: arpa-h.gov/explore-fund...

STOMP

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

arpa-h.gov

The Oklahoma Nathan Shock Center Translational Pilot Awards open this Wednesday, April 1! 🔗 For more information: oklahomanathanshockcenteronaging.org/translationa... #Geroscience

Submissions for the OKNSC Translational Pilot Awards are now open!

Oklahoma Nathan Shock Center@oknathanshock.bsky.social · 4mo ago

The Oklahoma Nathan Shock Center Translational Pilot Awards open this Wednesday, April 1! 🔗 For more information: oklahomanathanshockcenteronaging.org/translationa... #Geroscience

There is scant evidence to justify claims made by promoters behind the peptide craze. People should also know there are risks to taking these injections. Thankfully Nevada regulators helped hold some of these promoters accountable for violating state law: www.propublica.org/article/raad...

Nevada Regulators Fine Peptide Providers at Anti-Aging Festival Where Two Women Became Critically Ill

Three individuals, along with the group accused of supplying the peptides, were fined between $5,000 and $10,000 for their involvement in an incident at the Revolution Against Aging and Death Festival...

propublica.org

@trahan.house.gov Your support for ARPA-H is commendable, and I urge you also to act to protect researchers supported by NIA grants. Even if Congress restores funding levels, research can be sabotaged by low grant approval rates. Your support for NIA research is urgently needed.

Jeremy Berg@jeremymberg.bsky.social · 5mo ago

12/25

ARPA-H will “build the train tracks” for the first large clinical studies of aging interventions. https://scim.ag/4dcPEJj

U.S. agency will devote $144 million to studies that slow aging, extend quality of life

ARPA-H will “build the train tracks” for first large clinical studies of aging interventions

scim.ag

An informative overview on research and trials of mTOR-targeting interventions by Nicolas di Leo with a mention of @lamminglab.bsky.social, @arpa-h.bsky.social, and many others : norngroup.substack.com/p/advancing-...

Advancing Longevity Trials: Lessons from mTOR-Targeting Interventions

What two decades of trials can teach us about translating rapamycin to human aging.

norngroup.substack.com

🚨 The Human Ageing Genomic Resources Are at Risk For over 20 years, our Human Ageing Genomic Resources (HAGR) have supported ageing and longevity research. We are raising funds to secure their continuity while we pursue long-term funding. www.justgiving.com/page/human-a...

Support the Human Ageing Genomic Resources

Help Joao Pedro Magalhaes raise money to support University of Birmingham

justgiving.com

Nir Barzilai was elected to the Association of American Physicians: www.afar.org/news/afar-bo...

@liccardo.house.gov Congratulations to Stanford University in your district! They are one of the awardees in the @arpa-h.bsky.social PROSPR program. This is an important development for the Longevity Science Caucus. Thanks for being a member and supporting geroscience. arpa-h.gov/news-and-eve...

Research teams to add more healthy years to Americans’ lives as they age

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

arpa-h.gov

Most of us don’t just want longer lives, but more years of good health. PROSPR awardees are spotting early signs that health is slipping, building systems for aging clinical trials & testing new drugs that could be the 1st gen drugs to extend healthy years. Meet the teams: arpa-h.gov/news-and-eve...

🚨 BIOGAMI Proposers' Day Registration is closing soon – sign up by Feb. 18 at 5pm ET for in-person attendance, or by Feb. 19 at noon ET for virtual attendance. arpa-h.gov/explore-fund...

ARPA-H@arpa-h.bsky.social · 6mo ago

What if we could detect & repair the earliest stages of protein dysfunction in the body to eliminate diseases like ALS & Parkinson's? Our BIOGAMI program will crack the code on disordered proteins—and then harness that knowledge to force misfolded proteins back into line. arpa-h.gov/news-and-eve...

@lifebiosciences.bsky.social, founded by @davidsinclairphd.bsky.social & Tristan Edwards, helmed by CEO Jerry McLaughlin, has received @fda.gov IND clearance for cellular rejuvenation using partial epigenetic reprogramming in optic neuropathies. I'm so proud: www.lifebiosciences.com/life-bioscie...

Life Biosciences Announces FDA Clearance of IND Application for ER-100 in Optic Neuropathies

IND clearance marks the first ever cellular rejuvenation therapy using partial epigenetic reprogramming to reach human clinical trials BOSTON, January 28, 2026 – Life Biosciences, Inc., (“Life Bio”) a...

lifebiosciences.com

Aging Research and Drug Discovery (ARDD) has begun uploading video lectures from its Aug 2025 conference: www.youtube.com/@ardd3628/vi...

ARDD

This is the channel for the Aging Research and Drug Discovery meeting (www.agingpharma.org). We reserve the right to remove derogatory, personal and/or non-scientific comments.

youtube.com

BioAge Labs provides on update on its 2026 clinical plans for oral NLRP3 inhibitor: ir.bioagelabs.com/news-release...

Call on your house representatives to support a FY2026 budget bill that would preserve funding for NIH at the Senate Appropriations Committee approved level of $48.7B and adopt Senate language prohibiting a cap on indirect costs and limiting multi-year funded grants to levels consistent with FY2024

Loyal has achieved two of three components needed for FDA expanded conditional approval of its canine longevity drug: loyal.com/posts/loy-00...

One step closer to a dog longevity drug: What LOY-002’s safety milestone means to a practicing vet

The FDA recently accepted the Target Animal Safety (TAS) submission for LOY-002, our drug in development for senior dog lifespan extension. Our Director of Veterinmary Medicine, Brennen McKenzie, expl...

loyal.com

Essay by @martinbjensen.bsky.social on limitations of current aging clocks on metrics (accuracy, responsiveness, interpretability, stability, applicability, cost) in various intended uses (R&D, consumer health, clinical trials, FDA approval, medical care). norngroup.substack.com/p/do-we-have...

Do we have a useful aging clock?

13 years after the first 'aging clock' was published we're still measuring mouse lifespan and unable to run human aging trials. What's missing?

norngroup.substack.com

Thank you to everyone who attended Proposers' Day in Bethesda and get those Solution Summaries in by January 20! (2/2) arpa-h.gov/explore-fund...

AIR

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

arpa-h.gov

Hi! We are The Longevity Initiative, a new think tank and educational organisation working towards a world free from age-related disease, where longevity medicines are accessible to everyone. Find out more at our website, thelongevityinitiative.org 🐢

The Longevity Initiative

Learn how longevity science could help us all live healthier for longer—and what extending healthspan means for policy, ageing, and the economy.

thelongevityinitiative.org

We use OT to fund high-impact, high-risk research and development and attending a session offers significant advantages for researchers, companies, nonprofits, and government collaborators. Register to secure your spot! (2/2) solutions.arpa-h.gov/Events/OT-Co...