America's R1 universities educate ~8–9 million students (undergraduate + graduate) -> more than 1/3 of U.S. college students (vs. the ~0.6% of Ivies). Undermining this system threatens the institutions that train our workforce and drive scientific innovation. www.science.org/doi/10.1126/...

An American research crisis with real human consequences

Ivy League universities have dominated recent news headlines, having become popular targets for critics of higher education. But the threats they face—cuts to federal research funding, assaults on aca...

science.org

MIT ACCESS is an opportunity for undergraduates to explore cutting-edge research and graduate education in science and engineering. See for yourself what grad life is like at MIT! Applications due Aug 1: access.mit.edu @mitcheme.bsky.social @mitchemistry.bsky.social

📢 LOIs now open for CASI CASI aims to foster investigators who are integrating approaches from quantitative, computational, or physical sciences to address complex biological questions 🔗 Details & information: <https://buff.ly/LRHROHL> #bwfcasi #GrantOpportunity

The next generation of scientists will be a smaller cohort because of the policies of this administration: www.nytimes.com/2026/07/06/u...

Decline of Ph.D. Admissions Could Imperil a ‘Generation of New Talent’

nytimes.com

Calling all Scientists! Research Administrators! Deans! Fans of Science! No one is coming to save us. Here is your assignment. I have written a step by step, easy to understand "how-to" document to help you comment on the proposed OMB rule. elizabethginexi.substack.com/p/what-we-ne...

What We Need to do NEXT: OMB’s Proposed Federal Financial Assistance Rule (OMB 2026-10817)

What OMB’s Proposed Federal Financial Assistance Rule Means in Practice

elizabethginexi.substack.com

The public comment period closes approximately July 13, 2026 (45 days from May 29 publication). Comments must be submitted to regulations.gov, Docket OMB-2026-0034

Kristian G. Andersen@kgandersen.bsky.social · 2mo ago

And, here, in much more detail. This is an absolutely critical read for all federally funded scientists and institutions. Now is not the time to sit in the corner, hoping you won't be noticed - now is the time for action. elizabethginexi.substack.com/p/summary-of...

Excellent summary of how Vought’s proposed rule will destroy science. Please be ready to comment tomorrow, call Congress, tell your friends. If you’ve been waiting for the right moment to speak up, that moment is now.

elizabethginexi.bsky.social@elizabethginexi.bsky.social · 2mo ago

Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule. Russell Vought is going destroy American Science. elizabethginexi.substack.com/p/summary-of...

A pleasure to give @stanfordimmunology.bsky.social seminar last week for a few reasons: - to be invited by trainees - to visit the place that got me hooked on immunology - to share results from my lab @mitkochinstitute.bsky.social @mitdeptofbe.bsky.social @mitcheme.bsky.social Thanks for having me!

Honored to receive a Pershing Square Sohn Cancer Prize and excited about the work this award will support! Learn more about our efforts to target glycans to enable precision immunotherapies for cancer: pershingsquarephilanthropies.org/prize-winner... @mitdeptofbe.bsky.social @mitcheme.bsky.social

Jessica Stark — Pershing Square Philanthropies

Pershing Square Philanthropies - we bet on innovative leaders solving humanity’s big societal, environmental, and health challenges.

pershingsquarephilanthropies.org

MIT Koch Institute@mitkochinstitute.bsky.social · 3mo ago

Congrats to @jcstark.bsky.social on being named a 2026 Pershing Square Sohn Cancer Prize awardee, supporting bold, high-risk ideas w/ potential to transform cancer research. Her work explores how cancer-cell glycans can be harnessed for new approaches to precision immunotherapy. mit-ki.org/42kmCAX

Congrats to @jcstark.bsky.social on being named a 2026 Pershing Square Sohn Cancer Prize awardee, supporting bold, high-risk ideas w/ potential to transform cancer research. Her work explores how cancer-cell glycans can be harnessed for new approaches to precision immunotherapy. mit-ki.org/42kmCAX

Grateful to @natbiotech.nature.com for the opportunity to reflect on my scientific journey, including launching my lab @mitkochinstitute.bsky.social @mitdeptofbe.bsky.social @mitcheme.bsky.social www.nature.com/articles/s41...

Five questions with Jessica Stark - Nature Biotechnology

A builder and problem solver at heart, she is developing technologies to understand and engineer the roles of cell-surface sugars, called glycans, in the immune system.

nature.com

Five questions with Jessica Stark @jcstark.bsky.social go.nature.com/42sA99y

Five questions with Jessica Stark - Nature Biotechnology

A builder and problem solver at heart, she is developing technologies to understand and engineer the roles of cell-surface sugars, called glycans, in the immune system.

go.nature.com

We are searching for a talented administrative assistant to provide critical support for our team @mitkochinstitute.bsky.social. Learn more and apply: tinyurl.com/3r9crrbm Please share widely! #hiring #sciencejobs

New research grants in essentially all fields (as judged by NIH Institutes and Center missions) fell by 20-25% from fiscal year 2024 to fiscal year 2025. 2/5

"There is perhaps no stronger evidence of the [Trump] administration’s objectives to reduce the quality of the US scientific workforce than its treatment of the [NSF]’s flagship Graduate Research Fellowship Program," writes H. Holden Thorp in a new #ScienceEditorial. https://scim.ag/4d0fi3N

@biorxivpreprint.bsky.social Single-Cell and Spatial Methods for Multimodal Functional Glycan Profiling in Tissues www.biorxiv.org/content/10.6... @harvard.edu @broadinstitute.org @shaleklab.bsky.social @ragoninstitute.bsky.social @laurakiessling.bsky.social

Great to see our work to engineer AbLecs as a new immunotherapy modality featured in @natrevdrugdiscov.nature.com! www.nature.com/articles/d41...

Antibody–lectin chimeras: new checkpoint inhibitors in the toolbox

Discover the world’s best science and medicine | Nature.com

nature.com

Cancer cells use sugar-based immune checkpoints to suppress immune attack. New work from Jessica Stark & Carolyn Bertozzi shows that blocking these glycan checkpoints with AbLecs can release that brake & boost anti-tumor immunity across cancer types. news.mit.edu/2025/new-imm...

Vaccines, the most impressive public health intervention in medical history, and where we could be headed if there was not efforts to negate truth, facts, and evidence A great, open-access, review and perspective by @scientificdiscovery.dev

Researchers led by Dr. Jessica Stark (@jcstark.bsky.social) have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make #CancerImmunotherapy work for many more patients. 📰 MIT News: https://bit.ly/3YlpCeq

New online in @natbiotech.nature.com: Cancer immunotherapy benefits from antibody-lectin chimeras that block glyco-immune checkpoints.

Nature Biotechnology@natbiotech.nature.com · 8mo ago

Antibody-lectin chimeras for glyco-immune checkpoint blockade - @jcstark.bsky.social @carolynbertozzi.bskyverified.social go.nature.com/4aRDpk8

Congratulations @jcstark.bsky.social and the team, antibody-lectin chimeras (AbLecs), a new modality for cancer immune therapy, now published @natbiotech.nature.com. These bispecifics can block glyco-immune checkpoint receptor ligands directly at the immune synapse/activate immune effector functions

Nature Biotechnology@natbiotech.nature.com · 8mo ago

Antibody-lectin chimeras for glyco-immune checkpoint blockade - @jcstark.bsky.social @carolynbertozzi.bskyverified.social go.nature.com/4aRDpk8

Antibody-lectin chimeras for glyco-immune checkpoint blockade - @jcstark.bsky.social @carolynbertozzi.bskyverified.social go.nature.com/4aRDpk8

Antibody-lectin chimeras for glyco-immune checkpoint blockade - Nature Biotechnology

Cancer immunotherapy benefits from antibody-lectin chimeras that block glyco-immune checkpoints.

go.nature.com

A new jump forward in cancer immunotherapy blocking glycan sugar molecules (antibodies to lectin, AbLec) that releases the immune system brakes against many types of tumors @carolynbertozzi.bskyverified.social @jcstark.bsky.social www.nature.com/articles/s41...

Out now: We present antibody-lectin chimeras (AbLecs) as a molecular platform to target sugars, or glycans, for cancer immunotherapy. www.nature.com/articles/s41... www.nature.com/articles/s41... @mitkochinstitute.bsky.social @mitdeptofbe.bsky.social @mitcheme.bsky.social @stanford-chemh.bsky.social

Antibody-lectin chimeras for glyco-immune checkpoint blockade - Nature Biotechnology

Cancer immunotherapy benefits from antibody-lectin chimeras that block glyco-immune checkpoints.

nature.com

Fewer funded grants and graduate fellowships mean fewer innovative technologies and disease cures in our future. www.nytimes.com/interactive/...

The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine

A quiet policy change means the government is making fewer bets on long-term science.

nytimes.com

🚨 Attention undergraduate scientists and engineers! 🚨 Want to spend a summer doing research at MIT? Join us for the 2026 MIT Summer Research Program! Learn more and apply: oge.mit.edu/msrp/ @mitdeptofbe.bsky.social @mitcheme.bsky.social @mitkochinstitute.bsky.social

It's a great year to join the Leading Edge community 🕊️🤍

Leading Edge Fellows Program@leadingedgeprogram.bsky.social · 9mo ago

The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/

Great to see this story in print! Congrats @megtriesscience.bsky.social @douglaspdyer.bsky.social and team! Looking forward to sharing Megan's first contributions as a postdoc in our lab at @mitdeptofbe.bsky.social @mitcheme.bsky.social @mitkochinstitute.bsky.social soon... 👀

Megan Priestley@megtriesscience.bsky.social · 9mo ago

My PhD work is (finally) published in Science Signaling! And it made the cover! Here’s what we found 🧵⬇️ www.science.org/doi/10.1126/...

Why fundamental research is fundamental to progress, seeding major breakthroughs Editorial @nature.com this week And 7 basic science discoveries that changed the world nature.com/articles/d41... nature.com/articles/d41...