Very excited to announce I'm recruiting a ⭐ Research Assitant ⭐ for 3 years to work in my group on placental vascular development in mice and humans. See link below to apply to work with us at the @idrm.ox.ac.uk @dpagathenaswan.bsky.social Funded by @thebhf.bsky.social @biologists.bsky.social

Please check out our job post @biologists.bsky.social! We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens! bit.ly/3La9idq

Collaborative science is just so much fun! From our brilliant collaboration with Liz Robertson from @dunnschool.bsky.social; embryology, single cell omics and computational biology deliver new insights into the intricacies of blood and endothelial development. www.sciencedirect.com/science/arti...

🧪 Job alert 🔊 we are hiring a Research Assistant - join the Simões Group at DPAG-IDRM @ox.ac.uk supporting #cardiovascular development and regeneration research, working with #zebrafish and #human stem cell systems: my.corehr.com/pls/uoxrecru... @oxforddpag.bsky.social @idrm.ox.ac.uk (1/4)

Exciting news! Dr Jacinta Kalisch-Smith, @jkalism.bsky.social, has been awarded a BHF fellowship to explore how placental blood vessels support fetal growth and development. Her research could change how we detect and prevent complications during pregnancy. 🔗 Read more: shorturl.at/OVzqq

Feto-placental blood vessel development In this Review, Jacinta Kalisch-Smith @jkalism.bsky.social gives an overview of placental vascular development and pathologies in mice and humans and highlights key remaining questions in the field: doi.org/10.1242/dev....

Epigenetic regulation of placental vascularization - now published in Developmental Cell (www.sciencedirect.com/science/arti...). Congratulations & thanks to Stephanie Gehrs for fantastic work and paving the way of the www.augustinlab.de into the world of vascular epigenetics. There’s more to come!

Very happy to share I've written a review on placental vascular formation in mice and humans, now published in @dev-journal.bsky.social. journals.biologists.com/dev/article/... @idrm.ox.ac.uk Funded by the @thebhf.bsky.social

Feto-placental blood vessel development

Summary: This Review contains an overview of placental vascular development and pathologies in mice and humans and highlights key remaining questions in the field.

journals.biologists.com

Nice highlight on this recent @embojournal.org paper! www.theguardian.com/science/2025...

Moment of heart’s formation captured in images for first time

Time-lapse footage reveals cardiac cells in a mouse embryo begin to organise themselves during early development

theguardian.com

I had a some great news this week, being awarded an independent @thebhf.bsky.social fellowship. Thanks to the support from @idrm.ox.ac.uk @oxforddpag.bsky.social @ox.ac.uk colleagues past and present. Looking forward to the next few years investigating placental vascular development.

Institute of Developmental & Regenerative Medicine@idrm.ox.ac.uk · last yr.

🎉 Congratulations to Jacinta Kalisch-Smith who has just been awarded a 5 year Intermediate Fellowship from the British Heart Foundation. Her fellowship will study how placental blood vessels develop to understand the cause of neonatal heart conditions from early pregnancy @oxforddpag.bsky.social

✨Excited to share our work revisiting the developmental origins of mammalian lymphatic endothelial cells.✨ A summary of our key findings using scRNA-seq, snMultiome-seq and imaging to show the direct specification of mesenchymal progenitors to LECs🧵 #blutorial #blabstract tinyurl.com/LECspec

Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research

Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...

tinyurl.com

Very happy to share our work on lymphatic endothelial cell specification, which was published in Nature Cardiovascular Research this week.

Here in the UK, the HFEA is recommending changing the 14-day rule on human embryo research to allow culture up to 28 days. This will open up new avenues of research into previously inaccessible stages of development, and potentially provide new understanding of the causes of early pregnancy failure.

Limit on human embryo research should be extended to 28 days, says UK regulator

Experts say increasing law from 14 days could lead to breakthroughs in understand of miscarriages

theguardian.com

Side-hustle activated. Stoked to have this popular science piece out in Aeon Magazine: aeon.co/essays/after...

After 3,000 years of science, the embryo is very different | Aeon Essays

For 3,000 years, humans have struggled to understand the embryo. Now there is a revolution underway

aeon.co

Sorry to hear this Tom, hope someone can help you get some feedback. I certainly wouldn't have progressed without it.

Thomas Nicol@thomasnicol.bsky.social · 2y ago

...So when the @royalsociety.org says "due to the high number of applications we are unable to provide feedback", it sits badly. What little down time we have sunk into an application and the funder cant even say if it was on the right track, feels like a kick in the teeth to young researchers. 3/3

Nice to see our latest review published in @natrevmcb.bsky.social today – a collaborative exploration of mammalian extraembryonic development with @cwhanna.bsky.social for an invaluable epigenetic focus. @srinivas-lab.bsky.social www.nature.com/articles/s41...

Origin, fate and function of extraembryonic tissues during mammalian development - Nature Reviews Molecular Cell Biology

During mammalian embryogenesis, extraembryonic tissues are required for the patterning and morphogenesis of the embryo. This Review discusses how signalling networks and epigenetic modifications regul...

nature.com