Sharks might not be a natural biological group go.nature.com/4bFSncY

No such thing as a shark? Genomes shake up ocean predator’s family tree

Sharks might not be a natural biological group, with most species potentially closer kin to rays than to an oddball group of sharks.

go.nature.com

We are looking for PhD students or Postdocs with an interest in developing and using new methods for functional genetics following our recent work 👉 rdcu.be/e05Oo and academic.oup.com/nar/article/52

iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wild-type cells

Nature Methods - iFlpMosaics are a compendium of mouse lines and genetic tools for tissue-agnostic generation and analysis of genetic mosaics.

rdcu.be

Rui Benedito@ruibenedito.bsky.social · last yr.

The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil

Check out our latest preprint on the cellular mechanical basis of Voronoi tessellations in epithelia! This biophysics study is inspired by disordered tessellations observed in zebrafish hearts 🤓🐟💙 #SulaimaanLim #ChiuFanLeeLab arxiv.org/html/2512.13...

Please check out our job post @biologists.bsky.social! We are recruiting a Postdoc Scientist to develop cutting-edge tools and techniques for bioengineering human lymphatic networks, as part of an interdisciplinary collaboration with the group of Prof Dame Molly Stevens! bit.ly/3La9idq

I am absolutely delighted to share the invited speakers for our upcoming @bsdb.bsky.social "Molecules to Morphogenesis" meeting! Registration and abstract submission is now open - join us! bsdb.org/meetings/ March 23-26, 2026 - UK

The mathematics of starvation: how Israel caused a famine in Gaza

The mathematics of starvation: how Israel caused a famine in Gaza

Israel controls the flow of food. It calculated how much Gaza needs – but data shows how this is being withheld The mathematics of famine are simple in Gaza. Palestinians cannot leave, war has ended farming and Israel has banned fishing, so practically every calorie its population eats must be brought in from outside. Israel knows how much food is needed. It has been calibrating hunger in Gaza for decades, initially calculating shipments to exert pressure while avoiding starvation. Continue reading...

theguardian.com

The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil

My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...

Interphase cell morphology defines the mode, symmetry, and outcome of mitosis

During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity. We found that the shifts in cell morphology that shape tissues could conco...

science.org

Very excited to see the first Beisaw lab publication out in its final form 🥳🥳 rdcu.be/ei1I7 if you’re interested in zebrafish heart regeneration and how cardiomyocytes replace the fibrotic injured tissue (spoiler alert: macrophages play an important role), then read it here 👇

Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration

Nature Communications - Adult zebrafish are capable of heart regeneration, but how the collagenous injury site is replaced remains unclear. Here they provide an in-depth analysis of cardiomyocyte...

rdcu.be

Excited to see our work describing an external immune organ in the #zebrafish published in JEM! Big thanks to Aurora Kraus and @zebrafishmk.bsky.social and all of our other amazing collaborators including @edanfoley.bsky.social @biomarina-vg.bsky.social #WeinsteinLab rupress.org/jem/article-... 🧪

#onlywithHCR: @degrainger.bsky.social, @oliverastone.bsky.social, and their team reveal that lymphatic endothelial cells arise from specialized progenitors. #HCRimaging helped them to visualize endothelial progenitors in whole-mount mouse embryos. Learn more: www.nature.com/articles/s44...

Vascular Development: What determines whether an endothelial cell becomes part of an artery, a vein or a capillary? elifesciences.org/articles/106...

Congratulations Hans, @taijamakinenlab.bsky.social and team!

Hans schoofs@hansschoofs.bsky.social · last yr.

• Happy to announce that our paper in @nature.com is finally out! Thanks to the perseverance of @taijamakinenlab.bsky.social and our many collaborators we finally pulled it off! A small 🧵 www.nature.com/articles/s41... Laymen video: www.nature.com/articles/d41...

Excited to share this paper that is a long time coming from the lab on epigenetic/transcriptional regulation of organotypic endothelial specialization out today @naturecvr.bsky.social go.nature.com/4krSJqh

Mapping the transcriptional and epigenetic landscape of organotypic endothelial diversity in the developing and adult mouse

Nature Cardiovascular Research - Cantu Gutierrez et al. identify the common and unique transcriptional regulatory networks in the endothelium of six different organs throughout development, and...

go.nature.com

Some great images in this years @the-node.bsky.social image competition. Including my own "Thymus in the Spotlight" image taken in the @idrm.ox.ac.uk Zeiss CoE. Vote for your favorite here: thenode.biologists.com/vote-for-you...

My first blue update! Sharing my most recent illustration in a scientific journal.Thank you to @oliverastone.bsky.social who contacted me to adapt his concept as the cover for his paper in @naturecvr.bsky.social. These are the original design and the journal version!

We are excited to share our work on Context-dependent response of endothelial cells to PIK3CA mutation. A tour the force of many; thank you all for your invaluable contribution. @aangulou.bsky.social @ruibenedito.bsky.social @debocklab.bsky.social @sandradcastillo.bsky.social bit.ly/4blKSqa

Context-dependent response of endothelial cells to PIK3CA mutation

Cancer mutations in the PIK3CA gene cause congenital disorders. The endothelium is among the most frequently affected tissues in these disorders, displaying aberrant vascular overgrowth in the form of...

bit.ly

We have a postdoc position available in the lab! Come and work on lymphatic vascular development and regeneration. We use zebrafish, mouse, cells, tumour models and love imaging, genetics and genomics🔬 Come join us in Melbourne! www.seek.com.au/job/82157187...

Postdoctoral Fellow Job in Melbourne at Peter MacCallum Cancer Centre - SEEK

The Hogan laboratory is offering work for a highly motivated and skilled postdoctoral fellow in the area of lymphatic development and regeneration.

seek.com.au

Paper alert! Congrats to Lara, @cmdooley.bsky.social , @douglasadamoski.bsky.social and Thomas Juan for their great work on identifying the first example of Transcriptional Adaption in humans!🎉

@cmdooley.bsky.social · last yr.

1/? 🧬 New Breakthrough in Duchenne Muscular Dystrophy (DMD)! Our new paper in @Nature reveals how utrophin—a dystrophin “backup”—is upregulated in DMD. The key? Transcriptional adaptation (TA), triggered by mutant mRNA decay, not protein loss. [🔗 Link: www.nature.com/articles/s41...

Same same but different? How blood and lymphatic vessels induce cell contact inhibition - Our new short review is out @BiochemSoc @PPPublishing #BST #vascularbiology #contactinhibition #CIP #endothelial #junctions @dzhk_germany @UKEHamburg portlandpress.com/biochemsoctr...

iFlpMosaics are now published @naturemethods. A compendium of novel genetic tools and related methods for inducing and analysing genetic mosaics in a high-throughput manner.Tweetorial 👇 nature.com/articles/s4159…

@idrmoxford.bsky.social

If you're a non-UK scientist who wants to come to the UK for a postdoc, this year's Newton Fellowships are now open. You'll need a lab to host you (which could be me, but truly, could be any PI, so get in touch with someone you'd like to work with!) royalsociety.org/grants/newto...

Newton International Fellowships | Royal Society

This fellowship is for non-UK scientists who are at an early stage of their research career and wish to conduct research in the UK.

royalsociety.org

DPAG's Stone Group publishes new research in @naturecvr.bsky.social on the cellular mechanisms underpinning the formation of lymphatic endothelial cells @oliverastone.bsky.social @degrainger.bsky.social Read the paper here www.nature.com/articles/s44...

Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research

Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...

nature.com

Very happy to share our work on lymphatic endothelial cell specification, which was published in Nature Cardiovascular Research this week.

✨Excited to share our work revisiting the developmental origins of mammalian lymphatic endothelial cells.✨ A summary of our key findings using scRNA-seq, snMultiome-seq and imaging to show the direct specification of mesenchymal progenitors to LECs🧵 #blutorial #blabstract tinyurl.com/LECspec

Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research

Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...

tinyurl.com

Finally, out in print: "Mesodermal fibronectin controls cell shape, polarity, and mechanotransduction in the second heart field during cardiac outflow tract development." www.cell.com/developmenta...

Thank you for highlighting the paper, Tim!

Tim Petzold@timpetzold.bsky.social · 2y ago

Great paper from the @oliverastone.bsky.social lab, providing further evidence that lymphatic endothelial cell specification can occur independently of the venous state www.nature.com/articles/s44... Builds nicely on previous work from the @karinayaniv.bsky.social lab (Nicenboim, Nature, 2015)!

Where did our neck muscles come from?🧪 Here's our #evodevo #devbio deep dive feat. #zebrafish, mouse, axolotls, & more! Led by Eglantine Heude & Tajbakhsh lab at Pasteur, the team at National Museum of Natural History France, & lab alumni Karin Prummel & Rob Lalonde. www.nature.com/articles/s41...

Co-option of neck muscles supported the vertebrate water-to-land transition - Nature Communications

The evolutionary water-to-land transition involved the separation of the skull from the pectoral girdle, though these musculoskeletal changes have not been deeply characterised. Here they show that th...

nature.com

Latest preprint from the lab! Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish www.biorxiv.org/content/10.1...

Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish

The blood-brain barrier (BBB) protects the brain from circulating metabolites and plays central roles in neurological diseases. Endothelial cells (ECs) of the BBB are enwrapped by mural cells includin...

biorxiv.org