We have a new preprint, examining what happens at the single neuron level in humans while people emerge from anaesthesia. Link: www.biorxiv.org/content/10.6.... tldr: neurons in medial temporal lobe (and thalamus, albeit limited data) often show increases in activity way before overt responses 🧠🟦 🧠💻

New intracranial work published today in @plosbiology.org Frontotemporal network interactions causally support rapid concreteness judgments during reading Summary below 🧵 journals.plos.org/plosbiology/...

Frontotemporal network interactions causally support rapid concreteness judgments during reading

How the brain causally represents conceptual meaning with precise spatiotemporal dynamics remains unclear. This study shows through brain stimulation and intracranial recordings that concrete and abst...

journals.plos.org

We have a new preprint examining single neuron responses in humans undergoing TMS (www.biorxiv.org/content/10.6...). The excellent Charlie Dickey led the way, and I had the privilege to co-supervise this work with @coreykeller.bsky.social and @aaronboes.bsky.social 🧵 (1/7) 🧠🟦 🧠💻

Excellent fMRI work on auditory navigation, led by the wonderful @alexjbillig.bsky.social

Alex Billig@alexjbillig.bsky.social · 5mo ago

Out now: brain system supporting "navigation" through auditory (spectral density) space overlaps that for spatial navigation, incl. hippocampus & OFC. onlinelibrary.wiley.com/doi/10.1002/hbm.70492 w/ @imagingneurosci.bsky.social @uclearinstitute.bsky.social + Uni of Iowa & Newcastle Uni colleagues

Our new preprint is out! We show that deviance detection in auditory cortex conveys the theorised comparison of internal prediction to sensory input. Our data confirm this key assumtion that links theoretical models of sensory processing to experimental data. www.biorxiv.org/content/10.6...

Cortical deviance detection represents a canonical difference signal

Context modulates neural processing of sensory stimuli. Neural responses are suppressed to stimuli that are typical in their context and augmented to stimuli that deviate from their context. The latte...

biorxiv.org

Please repost: we're hiring! Apply now! 👉 can-acn.org/professor-re...

Are you curious about electrogastrography, but keep getting chicken-related results when googling "EGG"? We have the preprint for you! In this tutorial, we describe how to acquire and analyse gastric data from human participants. Plus FREE software! Read it here: arxiv.org/abs/2509.17260

fMRI signals “up,” but neural metabolism might be going “down.” In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes. rdcu.be/eUPO8 funds @erc.europa.eu #neuroskyence 🧵:

Our paper is out now in J Neuroscience (currently in "accepted paper" form). We directly record single neurons in human insula, as well as primary auditory cortex, while participants passively listen to simple sounds. @sfnjournals.bsky.social www.jneurosci.org/content/earl... (1/5) 🧠📈🧵👇

The human insula reimagined: Single neurons respond to simple sounds during passive listening

The insula is critical for integrating sensory information from the body with that arising from the environment. Although previous studies suggested that posterior insula is sensitive to sounds, these...

jneurosci.org

New paper just published with @evelinaleivada.bsky.social @garymarcus.bsky.social, Vittoria Dentella, Raquel Montero and Fritz Günther Fundamental Principles of Linguistic Structure Are Not Represented by ChatGPT bioling.psychopen.eu/index.php/bi...

My wonderful co-authors (including @alexjbillig.bsky.social) & I have just published a case report of acquired misophonia & amusia following right temporal resection (including posterior insula). This represents the first case of acquired misophonia. Please find the paper freely accessible below🧠📈

Alex Billig@alexjbillig.bsky.social · 8mo ago

With excellent colleagues at U Iowa including first authors Emily Dappen and @joelberger.bsky.social : a very rare case of acquired misophonia and amusia following right temporal resection: www.sciencedirect.com/science/arti... (and free til mid-Jan here: authors.elsevier.com/c/1mAun1M5IZ...)

As it's hiring season again I'm resharing the NeuroJobs feed. Add #NeuroJobs to your post if you're recruiting or looking for an RA, PhD, Postdoc, or faculty position in Neuro or an adjacent field. bsky.app/profile/did:...

@suthanalab.bsky.social outstanding talks at HSN and SfN. Really amazing work!

I rarely come on here or any social media, but wanted to share our latest preprint of large-scale human single neuron recordings during an auditory working memory task: doi.org/10.1101/2025... I'm very grateful to our patients, my co-authors and the funders. And to anyone who reads it :-) 🧠📈🧵👇(1/5)

Brain-wide single-neuron bases of working memory for sounds in humans

In order to understand the constantly changing acoustic world our brains must maintain elements of auditory scenes in memory. The neural mechanisms for this fundamental process remain unclear. Here, w...

doi.org

I am incredibly proud to share my first, first-author paper as a postdoc with @benhayden.bsky.social . How does the human hippocampus, known for encoding concepts, represent the meanings of words while listening to narrative speech? www.biorxiv.org/content/10.1...

Out now in Nature Comms. To learn a new word, we need to remember it. We track factors driving memory of novel words, showing which words we remember or forget is predictable across people, and isolate a distinct region of fusiform cortex sensitive to this memorability. 🧠📈 #VisionScience 🧠💬 🧵👇

Memorability of novel words correlates with anterior fusiform activity during reading - Nature Communications

To learn new written words, we need to be able to remember their associated letters. Here, the authors show the factors that predict how memorable or forgettable new words are and show a region of hum...

doi.org

Our new preprint is up now, wherein we directly record from a relatively large population of single neurons in human insula, as well as primary auditory cortex, while intracranial participants passively listen to simple sounds (tones/clicks). doi.org/10.1101/2025... (1/5) 🧠📈🧵👇

Human insula neurons respond to simple sounds during passive listening

The insula is critical for integrating sensory information from the body with that arising from the environment. Although previous studies suggest that posterior insula is sensitive to sounds, auditor...

doi.org

New results! Despite their varied molecular actions, anesthetics alter brain wave alignment in the same way. Convergent effects of different anesthetics are due to changes in phase alignment of cortical oscillations www.biorxiv.org/content/10.1... #neuroscience

Our new paper on tinnitus and the hippocampus is out now in Human Brain Mapping: doi.org/10.1002/hbm.... The TL;DR is that we are highlighting a role for the hippocampus that focuses on sustaining the memory of a phantom percept, based on current literature. 1/4 🧠📈 #PsychSciSky

Our study examining intracranial responses to vocoded speech, relevant to cochlear implants, is out now ( www.frontiersin.org/articles/10.... ), led by Kirill Nourski & Mitch Steinschneider. Some very interesting dorsal/ventral stream differences dependent on task performance.

Intracranial electrophysiology of spectrally degraded speech in the human cortex

Cochlear implants (CIs) are the treatment choice for severe to profound hearing loss. Variability in CI outcomes remains despite advances in technology and is attributed in part to differences in cort...

frontiersin.org

I'll be presenting the poster below at APAN this afternoon and SfN on Tuesday afternoon, based on the intracranial local field potential and unit data we collect at Iowa. Come and say hi! Thank you to my lovely colleagues and our patients 🧠🟦

Our work on decoding speech using high-density micro-scale recordings was published today in Nature Communications! We demonstrate the potential of high-spatial sampling technology for future neural speech prostheses. nature.com/articles/s4146… The thread below outlines our main findings.

Have you heard that PLOS Mental Health is now open for submissions? Learn more about this new global, multidisciplinary #OpenAccess journal: plos.io/MHOpen

We publish today with @alexwiesman.bsky.social in Progress in Neurobiology another advance in the fight against Parkinson’s disease. Slowing of 🧠 activity is not systematically an adverse effect of pathology: it can also be a sign of compensatory activity that preserves cognitive functions.

Adverse and compensatory neurophysiological slowing in Parkinson’s disease

Patients with Parkinson’s disease (PD) exhibit multifaceted changes in neurophysiological brain activity, hypothesized to represent a global cortical …

sciencedirect.com

Are you a neuroscientist who recently joined Blue Sky? Don't forget to like and pin #neuroskyence, the largest channel for all things brain-science related! You can post with #neuroskyence or 🧠🟦 ! #psychscisky 🧪 #academicsky bsky.app/profile/did:...

Two new misophonia papers from our group. First (bit.ly/mismi), led by Paris Ash and Sukhbinder Kumar examines the incidence of mimicry in misophonia. The second (bit.ly/SocMi, preprint) presents misophonia within a social cognitive framework (1/6)🧵in comments #Psychology #PsychSci 🧠🟦

Come join the lab! I'll be at SfN if you want to chat about the cool things we're up to or about the position.

Cogan Lab@coganlab.bsky.social · 3y ago

Do you have (or about to have) a PhD and are you interested in speech and intracranial recordings (seeg, ecog, and micro-ecog)? The Cogan Lab at Duke is looking for a postdoc! International applicants are welcome. Join us! coganlab.org/postdoc23

Our new paper is out now in Nature Communications, highlighting what happens in the brain during a semantic context task when you disconnect the anterior temporal lobe: www.nature.com/articles/s41... 🧠📈

Immediate neural impact and incomplete compensation after semantic hub disconnection - Nature Commun...

The human brain is a distributed system composed of highly interconnected hubs. Here, patients undergoing a rare operation reveal the immediate impact and compensatory brain network changes that occur...

nature.com

My colleague Phil Gander and I are looking to hire a postdoc for collaborative misophonia research in Iowa. We're keen for people who are interested and experienced in fMRI/EEG analyses, with the opportunity to learn analyses of human intracranial data: jobs.uiowa.edu/postdoc/view... #neuroskyence

Hi Bluesky peeps, a brief introduction - I'm a neuroscientist working with amazing intracranial patients in Iowa, recording single neurons and local field potentials, mainly to understand aspects of auditory cognition and pathological auditory processing #neuroskyence #introduction