Special thanks to Pietro Marcolongo, Urmi Bhattacharyya, @samomat.bsky.social , Dr. Antonia Bose, Dr. Stephan Kaczmarz, Gabriel Hoffmann, Daniel Rueckert & @vavatin.bsky.social #Neuroimaging #MRI #SciComm @fau.de @akmaier.bsky.social
Valentin Riedl
@vavatin.bsky.social
Brain scientist asking: How do we spend metabolic energy on processing information? https://valentinriedl.de/ | Professor for multiscale neuroimaging @FAU | NeuroEnergetics-lab @TUM | Award-winning documentary LOST IN FACE about Carlotta and her brain
Out now in @pnas.org We present a new metabolism-weighted brain connectome that incorporates each region’s energy expenditure into the mapping of brain connectivity. www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
pnas.org
Everybody in the "climate space" (which means everyone on earth...) needs to understand these mind-blowing figures. Google's "total electricity consumption jumped from 31 terawatt hours (TWh) in 2024 to 43 TWh in 2025." In ONE year. The AI corporate arms race is eating the world.
NEW BLOG FOR YOU Google's energy consumption numbers in their new climate report are mind-blowing. 2 years ago they flipped from linear to exponential growth, and their climate impact is blowing out, too. A WILD testament to the obscene bloat and waste of GenAI: ketanjoshi.co/2026/07/01/g...
Our new preprint is out!! The human brain runs on ~20 watts. Computers and modern AI systems require vastly higher energy. This gap raises a fundamental question: how does the brain compute so efficiently? In our new study, we take a critical step toward measuring and understanding this directly 1/3
Learning Shapes the Energy Cost of Neural Tasks https://www.biorxiv.org/content/10.64898/2026.07.01.735889v1
Out now in @pnas.org We present a new metabolism-weighted brain connectome that incorporates each region’s energy expenditure into the mapping of brain connectivity. www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
pnas.org
it‘s hot again in Bordeaux 😎 and Wednesday is neuroenergetics day: find Mahnaz‘s oral presentation and Samira‘s poster dates below and drop by for discussions! #ohbm2026 @samomat.bsky.social, @mahnazAshrafi
Join me at #ohbm2026 to discuss about the reliability of multiparametric, quantitative MRI on Wed and Thurs N°2502 :)
See our science at Deep Piction, how we use it to develop new precision medicine.
Where do therapeutics go in the body? SCP-Nano combines whole-body imaging and AI to map nanocarrier biodistribution at single-cell resolution, revealing both intended targets and unexpected off-target destinations. Our recent work at @nature.com Biotechnology: www.nature.com/articles/s41...
Samira's work made the cover of @natneuro.nature.com this month 🎉 🔗 nature.com/neuro/volumes/29/issues/5 I also want to highlight two recent comments that engage with our quantitative approach to interpreting the BOLD signal; both are worth reading (see below).
Multiplexed magnetic resonance imaging (MRx). www.nature.com/articles/s41... 22 measures incl. T1, T2, main metabolites in 14 min. A technical tour de force, but I'm not sure where/how it will find clinical applications.
Multiplexed magnetic resonance imaging - Nature
A new approach to magnetic resonance imaging, ‘multiplexed magnetic resonance imaging’, is reported, which enables high-resolution simultaneous multiparametric mapping of multiple molecules in standar...
nature.com
I didn’t expect a short video about an octopus to stay with me this long. At first, it looks like a simple, almost playful interaction. But the more you watch, the more something deeper emerges: a learning process unfolding between two completely different forms of intelligence. 🧵 1/
What a nice story about this learning process and this beautiful yet unconventional human-octupus interaction! youtu.be/PcWnQ7fYzwI?...
How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social
This looks like a significant discovery from Doris Tao's lab: Rapid concerted switching of the neural code in the inferotemporal cortex @nature.com "..our findings indicate that there is a previously unknown mechanism for neural representation:.." www.nature.com/articles/s41...
Rapid concerted switching of the neural code in the inferotemporal cortex - Nature
Face cells in the macaque inferotemporal cortex are initially able to detect faces and then rapidly switch to a face-specific neural code to discriminate between different face identities.
nature.com
fMRI signals “up,” but neural metabolism might be going “down.” In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes. rdcu.be/eUPO8 funds @erc.europa.eu #neuroskyence 🧵:
What started as a spinoff project for Madeleine's PhD became one of the most striking indications that glucose levels play an important role in regulating everyday stress responses. This shows the potential of biosensors to evaluate whether metabolism alters stress reactivity #neuroskyence 🩺
📣I’m excited to share our new preprint on how our body’s energy supply shapes everyday stress experiences: 📄𝐇𝐢𝐠𝐡𝐞𝐫 𝐠𝐥𝐮𝐜𝐨𝐬𝐞 𝐥𝐞𝐯𝐞𝐥𝐬 𝐛𝐮𝐟𝐟𝐞𝐫 𝐚𝐠𝐚𝐢𝐧𝐬𝐭 𝐞𝐯𝐞𝐫𝐲𝐝𝐚𝐲 𝐬𝐭𝐫𝐞𝐬𝐬 𝐥𝐨𝐚𝐝 www.biorxiv.org/content/10.6...
What if complex life began when evolution hit a search bottleneck? Across 6,500+ species, 🧬 length follow a scale-invariant law. At eukaryote origins, proteins plateau while 🧬 keep growing as noncoding regulatory DNA. Phase transition? www.pnas.org/doi/10.1073/... 👉 manlius.substack.com
One of the more provocative and important articles I've read in a while: A call for a "map" of neuroscience understanding and relationships between domains. apertureneuro.org/article/1388...
Bridging the epistemological divide in neuroscience to improve ontological clarity | Published in Aperture Neuro
By Giulia Baracchini, Eli Muller & 1 more. This perspective highlights the epistemological divide that arises from the wide variety of different experimental approaches... which in turn lead to ontolo...
apertureneuro.org
Our new review is out today! 𝗧𝗵𝗲 𝗘𝗻𝗲𝗿𝗴𝗲𝘁𝗶𝗰 𝗖𝗼𝗹𝗹𝗮𝗽𝘀𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗔𝗹𝘇𝗵𝗲𝗶𝗺𝗲𝗿’𝘀 𝗕𝗿𝗮𝗶𝗻: 𝗠𝗲𝘁𝗮𝗯𝗼𝗹𝗶𝗰 𝗜𝗻𝗳𝗹𝗲𝘅𝗶𝗯𝗶𝗹𝗶𝘁𝘆 𝗔𝗰𝗿𝗼𝘀𝘀 𝗖𝗲𝗹𝗹𝘀 𝗮𝗻𝗱 𝗡𝗲𝘁𝘄𝗼𝗿𝗸𝘀 We argue that Alzheimer’s disease is not just a problem of brain hypometabolism, but a disorder of metabolic inflexibility. onlinelibrary.wiley.com/doi/10.1111/...
The Energetic Collapse of the Alzheimer's Brain: Metabolic Inflexibility Across Cells and Networks
Metabolic inflexibility in Alzheimer's disease. Schematic illustrating the biphasic trajectory of metabolic activity relative to canonical Alzheimer's disease (AD) biomarkers. In the presymptomatic p...
onlinelibrary.wiley.com
🧵 What does it take to build a small, scrappy, and successful communication neuroscience lab? Our lab, @gongxuanjun.bsky.social, @rachaelkee.bsky.social, Allyson Snyder, Ziyu Zhao, and I put out heads together to answer this question. Here's what we came up with: link.springer.com/chapter/10.1...
Ever wonder how you read so fast? Your brain gets a head start—processing the next word before your eyes move. Our MEG + eye tracking study out in Nature Communications study from @thechbh.bsky.social reveals orthographic & semantic previews predicting reading speed www.nature.com/articles/s41...
Fast hierarchical processing of orthographic and semantic parafoveal information during natural reading - Nature Communications
Combining MEG, eye-tracking, and representational similarity analysis, this study shows that readers rapidly and sequentially extract orthographic and semantic information from upcoming words before fixation, supporting efficient reading.
nature.com
Hello! It has been a while, but for the Hector Fellow Academy I created a small project at the interface of neuroscience and music. In short, it is like a neuro-jukebox of projects of friends and colleagues integrating music and art. I thought it would be nice to share here cng-lab.github.io/kiosk
NEUROSONICS
cng-lab.github.io
Nature research paper: Mitochondrial origins of the pressure to sleep go.nature.com/40oC7Y4
Mitochondrial origins of the pressure to sleep - Nature
Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.
go.nature.com
Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
science.org
At today's layer-fMRI seminar, @ofgulban.bsky.social presented stunning high resolution vein mapping tools. It left me quite excited. youtu.be/0V8fSjo2T2w?...
Faruk Gulban: Meso Veins Meet Layer fMRI in High-Speed Data Exploration for the New Mesoscopic Era
YouTube video by Layer fMRI
youtu.be
Your brain functions not only as a thinking organ but also as a miniature water factory. We here calculate how much water neuronal mitochondria produce by glucose oxidation: 300-400 ml. Of that amount, 100 ml go into brain's interstitial fluid. fluidsbarrierscns.biomedcentral.com/articles/10....
A budget for brain metabolic water production by glucose catabolism during rest, rises in activity and sleep - Fluids and Barriers of the CNS
Maintaining brain fluid homeostasis is of critical importance for creating a stable environment conducive to optimal neuronal functioning, nutrient distribution, and waste product removal. In this stu...
fluidsbarrierscns.biomedcentral.com
The brain’s energy landscape as a potential window into brain health www.nature.com/articles/d41... (study led by Martin Picard and Michel Thiebaut de Schotten)
First map of human brain mitochondria is ‘groundbreaking’ achievement
Hundreds of cubes of human brain tissue help scientists to chart the energy-making capabilities of various brain regions.
nature.com
Have questions about the ISMRM MiniHub in Lille, France? Get all your questions answered in an informal drop-in Zoom session with the Organizing Committee. Whether you're already registered or considering attending, stop by and ask us anything! Register now: ow.ly/8Rgx50V6Xgr #ISMRM #ISMRMMiniHub
Thanks to all of the NIHers and their friends who reached out to me. I am still here (DM me or Signal jeremymberg.78) I still have a very incomplete picture but based on what I have been told, the damage to NIH and to many wonderful people who work(ed) there is/was impossible for me to imagine 1/n
Synaptome architecture shapes regional dynamics in the mouse brain | www.biorxiv.org/content/10.1... Led by Justine Hansen Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️
Neurons primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice. By @giorgiag-sciwriter.bsky.social www.thetransmitter.org/metabolism/f...
Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.
thetransmitter.org