Juan Turnes
@jturnes.bsky.social
Chief of Gastroenterology & Hepatology at University Hospital of Pontevedra, Spain | ➡️ AI in Medicine | EASL SoMe advisor | Associate Editor at Liver International #LiverSky #GIsky #MedSky
Nuestro Servicio de Digestivo recibe el Premio Ciudad de Pontevedra 🙌 Un premio como este, de los ciudadanos a los que nos debemos, es un honor que supera con creces cualquier otro. Y un refuerzo extra para seguir avanzando e innovando todos juntos 💪
The greatest review written on liver biopsy: indications, interpretation, and its future By Dr Purva Gopal and colleagues in HepCommJournal Open access journals.lww.com/hepcomm/full... #liversky #pathsky
Long-term risk of chronic liver disease in patients with celiac disease: a nationwide population-based, sibling-controlled cohort study New research in The Lancet Regional Health - Europe www.thelancet.com/journals/lan... #GastroSky #LiverSky #MedSky
Long-term risk of chronic liver disease in patients with celiac disease: a nationwide population-based, sibling-controlled cohort study
CeD is associated with a persistently increased risk of any incident CLD, although the absolute risk is low. Physicians should be vigilant to early signs of liver dysfunction in patients with CeD.
thelancet.com
There is urgent need for clinical trials for #HBV in #Africa. Studies must deliver: 1. Quick start-up 2. Site potential, access to participants 3. High quality research leading to impact www.thelancet.com/journals/lan... 🧪 #HepSky #LiverSky @mariondelphin.bsky.social @crick.ac.uk
Un estudio revela que los datos utilizados para entrenar la #IA están concentrando el poder en manos de unas pocas empresas, creando un oligopolio alineado con los intereses y objetivos de corporaciones con fines lucrativos www.technologyreview.es/s/16958/asi-...
Admittedly the cool name of the study group first caught my 👁️ POSEIDON study group showed ✅alfapump 📉need for LVP ✅similar complications ✅improved QOL @amcollegegastro.bsky.social journals.lww.com/ajg/abstract... #liversky
The key may be in the selection. There are so many variables (types of surgery, types of decompensation) that it is impossible to address from a prospective study at this point in time. It may be worthwhile to have a registry to help glean what is futile versus what is possible.
Key recommendations in portal vein thrombosis in patients with cirrhosis: ✅Identify recent thrombosis and extent ✅Anticoagulate if recent & >50% obstruction ❌ No anticoagulants if chronic cavernomas ✅DOACs safe if compensated 🤏 TIPS sometimes 💡 Image every 3m doi.org/10.1053/j.ga... #LiverSky
Q: Does gender play a role in GI symptoms? menopause? fascinating study. A: women have more symptoms of GI disorders than men, & there are different symptoms w/age, maybe b/c hormone changes #menopause onlinelibrary.wiley.com/doi/pdf/10.1...
Sex Differences, Menses‐Related Symptoms and Menopause in Disorders of Gut–Brain Interaction
Our global epidemiology study shows symptom differences within the five most common DGBI based on sex, menopause, age, and menses. Sex hormone-mediated effects may contribute to greater symptom burde....
onlinelibrary.wiley.com
Ulcerative colitis in pts with PSC (compared to UC w/o PSC) - more extensive (pancolitis) - milder disease course - heavier disease burden on right - rectal sparing + ileitis - higher risk of dysplasia and colorectal cancer (annual screening) #IBDSky #LiverSky #GISky @natrevgastrohep.bsky.social
I once lost a debate in spectacular fashion to @brettefortune.bsky.social. Popular vote landslide AND electoral college He was for early TIPS after variceal bleeding. I was against My points were: #liversky
Juan Turnes@jturnes.bsky.social · 2y ago⚠️ A recent study in patients with cirrhosis and portal hypertension shows that preoperative placement of TIPS is associated with increased postoperative mortality 🤨 doi.org/10.1097/hc9.... #LiverSky #MedSky
⚠️ A recent study in patients with cirrhosis and portal hypertension shows that preoperative placement of TIPS is associated with increased postoperative mortality 🤨 doi.org/10.1097/hc9.... #LiverSky #MedSky
Albumin is the closest thing to a "universal remedy" in cirrhosis We use it to treat different complications, with good evidence but also with debatable or negative evidence Excellent analysis by Jonel Trebicka & @ggarciatsao.bsky.social doi.org/10.1097/hep.0000000000000521 #LiverSky
Decompensated cirrhosis has often been considered the irreversible, terminal stage of liver disease, but this is not actually always the case Have you heard of the concept of cirrhosis "recompensation"? ➡️ doi.org/10.1016/j.jhepr.2024.101233 #LiverSky
Today marks the end of my journey as Associate Editor at Liver International. It’s been a fantastic experience, and I’m confident the journal will continue to grow 📈 I encourage researchers to submit their valuable work and contribute to its success! #liverSky
⁉️ Crees que la implantación de la #IA generativa en tu trabajo es lenta o inexistente? @emollick.bsky.social lo explica en Co-Intelligence: 🚫 Exceso de centralización y burocracia 🐢 Estrategias obsoletas 🔑 El verdadero poder está en quienes conocen los problemas reales y ya están probando soluciones
Early Terli Giving terlipressin at lower creatinines (1.5-2.0) or within 12 hours of presentation (skipping the “albumin challenge”) 1. From the RCTs journals.lww.com/hepcomm/page... 2. Pilot trial doi.org/10.1007/s106... #liversky
Image Gallery : Early treatment with terlipressin in patients with hepatorenal syndrome yields improved clinical outcomes in North American studies : Hepatology Communications
journals.lww.com
OpenAI alerta sobre las capacidades de engaño en las IAs, tras descubrir intentos de «autoconservación» en ChatGPT | #IA | por @Alvy www.microsiervos.com/archivo/ia/c...
Dicen que ChatGPT se ha marcado un «Black Mirror» intentando «escapar» para salvarse de sus ser borrado por sus creadores
OpenAI alerta sobre las capacidades de engaño en las IAs, tras descubrir intentos de «autoconservación» en ChatGPT.
microsiervos.com
Over on the Twitter I have liked hundreds of match day celebrations Observations: 1. Bluesky still needs more value for learners and research discussions. It is growing but needs to be sustained 2. Match day reminds: America and American medicine still attracts the worlds best and brightest
What do hepatic encephalopathy and irritable bowel syndrome have in common? Read this hot take from @jasmohanbajaj.bsky.social and @markpimentelmd.bsky.social in #AJG on whether HE is the original disorder of gut brain interaction (DGBI) #GISky #LiverSky Link: journals.lww.com/ajg/fulltext...
We’re serious about @bsky.app’s future 🤝
Claes de Vreese@claesdevreese.bsky.social · 2y agoNot only does @altmetric.com include 🦋 in it’s metrics, they also have Bluesky as part of their example and info pages 👏🏼 ☀️ Now they just need to adjust the example with more engagement from 🦋 than from X … 🚀 😉 @academic-chatter.bsky.social www.altmetric.com/about-us/our...
The siRNA xalnesiran with or without an immunomodulator in chronic hepatitis B - the Piranga ph 2 study www.nejm.org/doi/pdf/10.1... #MedSky #LiverSky #IDSky
Xalnesiran with or without an Immunomodulator in Chronic Hepatitis B | NEJM
Xalnesiran, a small interfering RNA molecule that targets a conserved region of the hepatitis B virus (HBV) genome and silences multiple HBV transcripts, may have efficacy, with or without an immun...
nejm.org
Systematic review & meta-analysis of locoregional therapies for #HCC in @jama.com network open ✅Inclusion: RCTs with PFS and OS as endpoints ✅Conclusions: Resection > thermal ablation ~ RT ~ HAIC > embolization #oncsky #radonc #radsky #liversky ja.ma/3ONRpQ1
Locoregional Therapies for Hepatocellular Carcinoma
This systematic review and meta-analysis compares findings from randomized clinical trials on the use of locoregional therapies as monotherapy or combination therapy in the treatment of nonmetastatic ...
ja.ma
3-yr data for SURMOUNT-1: up to 20% TBW loss w/ #tirzepatide @elilillyandco.bsky.social 15 mg dose maintained. 94% risk reduction in diabetes among prediabetics. Mostly GI AEs almost all in first 20 weeks. #liversky
Tirzepatide for Obesity Treatment and Diabetes Prevention | NEJM
Obesity is chronic disease and causal precursor to myriad other conditions, including type 2 diabetes. In an earlier analysis of the SURMOUNT-1 trial, tirzepatide was shown to provide substantial a...
nejm.org
Mañana cuento en el congreso de Endocrinología SEEDO2024 nuestro proyecto de asistente de #IA generativa con Atención Primaria, y en la diapositiva inicial hay una incorporación sutil que utilizo por primera vez ...
🔥¿Esófago de Barrett sin síntomas de reflujo? 🔥 7% Barrett en 👤 con síntomas de reflujo VS 2,2% en 👤sin síntomas 🟠Sin síntomas: 0,2% Barrett CON displasia ¿Perdemos pacientes en el cribado? ¿En qué factores de riesgo nos fijamos? 🧐 📑: linkinghub.elsevier.com/retrieve/pii...
a close up of a burning fire with a black background
ALT: a close up of a burning fire with a black background
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