Juan Reguera

@juanrv.bsky.social

Scientist. Research Director @ INSERM. Director of the AFMB lab in Marseille. Head of the ViMaC team. Working on structural virology and infection.

I'm so proud to share these incredible findings from our collaborative work between my team and Amara's lab about Alphaviruses, particularly the chikungunya virus!! We show nsP3 protein as part of replication complexes and cytoplasmic granules forming unexpected tubular scaffold🤔 rdcu.be/dT3Iy 🧪🧬🧶

Alphavirus nsP3 organizes into tubular scaffolds essential for infection and the cytoplasmic granule architecture

Nature Communications - The role of alphavirus nsP3 protein is not entirely clear. Here, through structural analysis the authors show that CHIKV nsP3 polymerizes to form tubular scaffolds in both...

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