Our fingerprint analysis work has now been published 🎉 --> link.springer.com/article/10.1... Also check out our small helper library #chemap --> github.com/matchms/chemap (work together with @julianpollmann.bsky.social) #cheminformatics #openscience #Python

Count your bits: fingerprint benchmarking to assess broad chemical space representation - Journal of Cheminformatics

Quantifying molecular similarity is a cornerstone of cheminformatics, underpinning applications from virtual screening and nearest-neighbor search to chemical space visualization and the evaluation of...

link.springer.com

Thanks Canyon, the only Domain where I could escape the AI Hype was riding my Bike: now AI ist integrated into a Road Bike. www.rennrad-news.de/news/canyon-...

Canyon stellt Rennrad der Zukunft mit KI und Rundum-Radar vor

Canyons neues KI-Rennrad der Zukunft erkennt Gefahren, bevor sie entstehen, und könnte schwere Unfälle verhindern.

rennrad-news.de

New post: Tagging my blog with BERTopic and LLMs. I suspect as token costs increase, we'll see more blended traditional ML/LLM systems. And, in general, they work really well! vickiboykis.com/2026/05/18/t...

Tagging my blog posts with BERTopic and LLMs

LLMs mean you still need a human in the loop, but in a different part

vickiboykis.com

Really looking forward to #PyConDe & #PyData 2026 edition! Some open Missions: ☑️ Soak in everything regarding Knowledge Graphs ☑️ Solve open mysteries in Python Multiprocessing ☑️ Meet new people and old friends ☑️ get a feel for the hot topics (except obvious ones) get there (partially) & back by bike

Just updated our preprint on benchmarking molecular fingerprints! --> www.biorxiv.org/content/10.1... Some key points - Count fingerprints should be the default (not binary!) - Unfolded fingerprints are often worth it. - Larger radius Morgan or FCFP fingerprints are good first bets.

Work done with @julianpollmann.bsky.social at @zdd-hsd.bsky.social Code: - Central functionalities are now pip installable --> github.com/matchms/chemap - Notebooks for experiments --> github.com/florian-huber/molecular_fingerprint_comparisons #openscience #opensource #cheminformatics #python

Haftbefehl shows that Germany loves art born from alienation – just not the people who create it

Haftbefehl shows that Germany loves art born from alienation – just not the people who create it

A hit Netflix documentary about Germany’s favourite rapper demonstrates how popular the aesthetics of migrant life are – just as politicians debate how to remove it from inner cities

theguardian.com

New #matchms release (0.31)🚀 With functionalities that were on our TODO list for a looooong time: Flash Entropy and BLINK scores! The new "FlashSimilarity" allows computing modified cosine, spectral entropy etc., about 100x faster (or more if you use Linux). #Python #opensource #massspec

4/4 We also highlight options for count fingerprints, such as log-counts and IDF weighted counts. The latter can be used to adjust the bit importance to a dataset of your choice. An example use-case are chemical space visualizations. Preprint: www.biorxiv.org/content/10.1...

3/4 A huge issue is bit collisions. Fingerprints with a high bit occupation (RDKit, MAP4) often lead to (1) arbitrary misinterpretations, (2) shifts to high Tanimoto scores, (3) very different handling of small and large molecules. --> Consider using sparse fingerprints! --> Morgan >> MAP4 / RDKit

2/4 We focused on weaknesses of the fingerprints. Many show frequent duplicates, so same fingerprint for different compounds. Most problematic: this can include *very* different compounds ending up with identical fingerprints. - MAP4 >> Morgan-type >> daylight - count >> binary #cheminformatics

New preprint out! 1/4 @julianpollmann.bsky.social and I went down several rabbit holes to assess some commonly used molecular fingerprints. Bottom line: For large datasets, make an effort to select suitable settings. "We used Tanimoto" is not good enough. --> www.biorxiv.org/content/10.1...

was @tante.cc sagt

Wir dachten, KI würde uns irgendwann durch Terminator-Roboter versklaven. Aber wir werden durch Bequemlichkeit versklavt.

Hello @pyconde.bsky.social Curious to listen to some interesting Talks and meet new people 😀

First draft online version of The RLHF Book is DONE. Recently I've been creating the advanced discussion chapters on everything from Constitutional AI to evaluation and character training, but I also sneak in consistent improvements to the RL specific chapter. rlhfbook.com

„Bei der #SPD haben noch die Mitglieder die Chance, die Notbremse zu ziehen und den Abbau wichtiger Grundrechte zu verhindern. Wir appellieren daher an die Sozialdemokraten: Stimmt dieser Überwachungsliste nicht zu!“ 🤝👏 @ccc.de

I think this is an important point that we missed the last 10y. We need to call out fiction as fiction and fighting for reality (can be boring, but it’s real). Reality is, there is no AGI, just language models. If you think they are giving you some truth, the stupidity is on you, not the LLM.

Mark Riedl@markriedl.bsky.social · last yr.

This isn’t a report, this is a fiction writing exercise www.nytimes.com/2025/04/03/t...

👨‍🏫 Can you help spread the word? Our community supports future #AI professionals like engineers and data analysts. With backing from PySV and Pioneers Hub, we provide students free virtual passes to Germany's top AI conference. Learn more at 2025.pycon.de/blog/free-re....

Enabling the Next Generation in AI & Open Source: Free Remote Tickets for Students at PyCon DE & PyData

Join PyCon DE & PyData 2025 in Darmstadt (Frankfurt), April 23-25! Germany’s largest Python and Data Science conference with talks, workshops, and community events like DjangoGirls and sprints. Be…

2025.pycon.de

Nice keynote by @tante.cc for the opening of @zdd-hsd.bsky.social #HSD

Die Vorbereitungen für die Einweihung des #ZDD laufen auf Hochtouren! Wir freuen uns auf morgen.

Stanford scholars introduced an open-source AI agent that learns how to navigate websites by mimicking childhood learning – an approach that could lead to more efficient, transparent, and privacy-conscious AI: hai.stanford.edu/news/an-open... @chrmanning.bsky.social @shikharmurty.bsky.social

An Open-Source AI Agent for Doing Tasks on the Web | Stanford HAI

NNetNav learns how to navigate websites by mimicking childhood learning through exploration.

hai.stanford.edu

#IchBinHanna & der 🐘 senden 1 Botschaft in die Koalitionsverhandlungen! #WissZeitVG @drkeichhorn.bsky.social @kubon.bsky.social

Interesting paper on Human Cognition in the Age of #AI or how not to brainrot arxiv.org/html/2502.12...

Die amerikanische Forschung ist auch für Deutschland wichtig. Das ist ja kein Wettbewerb, den wir gewinnen wollen. Wenn es anderen schlechter geht, wirkt sich das auch auf uns und unseren gesellschaftlichen Fortschritt aus.

It is super weird how little reception David Golumbia's last book "Cyberlibertarianism" has had. I mean I know why, he dropped a bunch of uncomfortable truth bombs there but it's still weird how little that book is talked about. It is probably the most important book about tech in the last decade.

I helped build a government AI system. DOGE fired me, rolled the AI out to the whole agency, and implied the AI can do my job and the jobs of the others they've fired. It can't. But, what DOGE accidentally revealed about themselves in the process is fascinating. 🧵

A friend pointed out that the quasi-religious way so many tech guys talk about AI is in part because they don't want to grapple with the guilt of what they do; AI is a God, AI will fix it. No need to be responsible for what you put in the world. I can't stop thinking about that.

Faine Greenwood@faineg.bsky.social · last yr.

The most dangerous thing about AI chat bots is how many men with political power treat them *exactly* and unquestioningly like actual Ancient Greek oracles.

Heftig. Laut Datenbank sind alle meine 4 Bücher - 3 davon zusammen mit @pialamberty.bsky.social verfasst - im Datensatz enthalten.

Damon Beres@damonberes.com · last yr.

NEW: LibGen contains millions of pirated books and research papers, built over nearly two decades. From court documents, we know that Meta torrented a version of it to build its AI. Today, @theatlantic.com presents an analysis of the data set by @alexreisner.bsky.social. Search through it yourself:

📢 #ACL2025NLP Student Research Workshop CFP is out 🙌 👉 2025.aclweb.org/calls/studen... Send your paper by ⏰ May 18th, 2025 🚀 #nlproc