@jury-lab.bsky.social
Translational research @ucl.ac.uk focusing on lipid metabolism defects in autoimmunity. Special interest in autoimmune rheumatic disease, haemophagocytic lymphohistiocytosis (HLH), cardiovascular risk and immunogenicity
It's women and girls in science day! What a great opportunity to highlight the amazing women in our dept.. @dianaematei.bsky.social @clairebeesley.bsky.social @drsianh.bsky.social @jury-lab.bsky.social @ciurtinlab.bsky.social @heather--cross.bsky.social @oliviabracken.bsky.social.
📣 We’re getting ready to host our 3rd Annual Conference next year and this time, we’re heading to Birmingham! 📅 16 April 2026 📍 The Birmingham Conference & Events Centre, B5 4EW 💯 Save the date and keep an eye out for more updates!
🚨New paper from the lab! Type I interferon endotypes drive divergent clinical trajectories in childhood-onset SLE uncovered through a novel systems immunology approach 📖Read here in Annals of the Rheumatic Diseases: doi.org/10.1016/j.ar... 🙏Huge thank you to all co-authors, funders, and patients!
Redirecting
doi.org
Delighted to share our new @natrevrheum.nature.com article: “Insights into the pathogenesis of childhood-onset SLE in the past decade” Grateful to an amazing team of co-authors and editors for building and shaping this work. We hope it helps the field and guides future discoveries.
Nature Reviews Rheumatology@natrevrheum.nature.com · 9mo ago
Now more than usual (since I'm considering applying for a sex-differences based fellowship) I enjoyed and appreciated @ciurtinlab.bsky.social talk #BSI25! We really really need to sex-dissegregate our data!! ♂️♀️
So sorry I couldn’t be there to celebrate your amazing achievements @ciurtinlab.bsky.social. Many congratulations
UCL Dept of Aging, Rheumatology & Regenerative Medicine@arrdept-ucldom.bsky.social · 10mo agoCongratulations 🥳 to Prof Ciurtin @ciurtinlab.bsky.social who will deliver the 2025 Lady Estelle Wolfson Lecture in Translational Medicine at the Royal College of Physicians today! Coziana will focus on improving risk stratification and management of cardiovascular risk in young people with lupus.
New systematic review of pregnancy associated HLH - 104 pregnancies - commonest cause infections (EBV, CMV, HSV, parvo) - followed by SLE, stills, lymphoma - 4/14 tested has positive genetics - 40% no known cause onlinelibrary.wiley.com/doi/epdf/10.... 1/6
Hemophagocytic Lymphohistiocytosis in Pregnancy: A Systematic Review of Case Reports and Case Series
Aims Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening syndrome caused by excessive immune activation, leading to severe inflammation and multi-organ failure. While adult-onset HL...
onlinelibrary.wiley.com
🤰🤱🩸♀️♂️ ✅UK based Rheumatology healthcare professional? E.g., Consultant, SpR, Nurse, Physio etc working in rheum? Please spend 5 minutes completing our survey mapping access to reproductive services for rheum patients across the UK. Thank you and please share! qualtrics.ucl.ac.uk/jfe/form/SV_...
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Second talk of the PhD ✅ Thank you so much to the @london-immuno.bsky.social for selecting my abstract on sex hormone/chromosome driven mechanisms of cSLE risk #LIG2025 #LIG25 🧬 🦠 @georgearobinson.bsky.social @ciurtinlab.bsky.social
This was a fantastic celebration yesterday - thanks to the @thelisterinstitute.bsky.social and @arrdept-ucldom.bsky.social and the wider division of Medicine for all their support 😊
The Lister Institute of Preventive Medicine@thelisterinstitute.bsky.social · last yr.We were so inspired by @bcellsrosser.bsky.social at her Lister Prize presentation this week! @ucl.ac.uk
Exciting new position in #arrdept alumni @madhvimenon.bsky.social lab 🧬
Madhvi Menon@madhvimenon.bsky.social · last yr.🚨 The Menon lab is hiring a postdoc! Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social Please help spread the word #ImmunoSky www.jobs.manchester.ac.uk/Job/JobDetai...
💉 Antiphospholipid Syndrome (#APS) is an autoimmune disorder that requires our urgent attention. 🔬 Thanks to your support, we've been able to fund researchers like Dr Thomas McDonnell. His ground-breaking work is advancing our understanding of APS, paving the way for better treatments.
@mcdonnelllab.bsky.social · last yr.Happy to share our newest paper in JTH, revealing novel structures of B2GPI in the presence of plasmin which alter antibody binding www.jthjournal.org/article/S153...
Hemophagocytic Lymphohistiocytosis 🔹Life-threatening syndrome of overwhelming inflammation 🔹Is crucial to search and treat the underlying trigger 🚩Fever, #Splenomegaly, #Cytopenia, #hyperferritinemia, #hypertriglyceridemia, bone marrow #hemophagocytosis #HLH @nejm.org www.nejm.org/doi/pdf/10.1...
Hemophagocytic Lymphohistiocytosis | NEJM
HLH, a cytokine-mediated hyperinflammation syndrome, causes fever, pancytopenia, and hemophagocytosis and is often fatal. Antiinflammatory agents, etoposide, and interferon-γ antibody are the main ...
nejm.org
Thank you so much! 😁 #EULAR2025 was an amazing first conference talk and I am so pleased and grateful to have been featured in the highlights as well!
UCL Dept of Aging, Rheumatology & Regenerative Medicine@arrdept-ucldom.bsky.social · last yr.Our department has had a stellar week at #EULAR. Special congrats to @heather--cross.bsky.social for not only having her first conference talk of her PhD but also having presented as a translational immunology highlight ✨
Nailed it! 👏
George Robinson@georgearobinson.bsky.social · last yr.@heather--cross.bsky.social presenting very soon on sex hormone/chromosome driven mechanisms of cSLE risk #EULAR2025! Join us in room A1 to hear some super interesting research! 🧬 🦠 @ciurtinlab.bsky.social @arrdept-ucldom.bsky.social Fantastic session with Jean-Charles Guery and Amy Roberts too 👇
It's official! Congratulations to everyone selected for the International Union of Immunological Societies (IUIS) #RisingStars2025 Cohort! I can't wait to meet you all at #IUIS2025 and share our research! Thank you to @iuis-online.bsky.social and @britsocimm.bsky.social for the nomination @ucl.ac.uk
International Union of Immunological Societies@iuis-online.bsky.social · last yr.IUIS and its Early Career Committee are thrilled to announce the IUIS #RisingStars2025 Cohort! 🌟 https://loom.ly/f5Gq1f8 Fifteen exceptional early-career scientists from across the globe to join our #RisingStars Program Don’t miss your chance to meet them https://loom.ly/CwagY2g
@simonyona.bsky.social et al show that quantify the ephemeral circulating lifespan of human cDC & propose functions of cDC & their precursors that are rapidly recruited to sites of #inflammation rupress.org/jem/article/... 📘 In Clinical #Immunology Collection: rupress.org/jem/collecti... #FOCIS2025
I feel incredibly honoured and privileged to receive this award and recognition. I ♥️ the @britsocimm.bsky.social. If you're not yet a BSI member, do sign up and become part of this amazing and supportive community, with an excellent #researchculture
British Society for Immunology@britsocimm.bsky.social · last yr.And it's the moment you've all been waiting for... time to announce our first winner! The winner of the 2025 Outstanding Contribution to the BSI Award is…. Professor Leonie Taams, @taamslab.bsky.social Congratulations on your achievement!
This month in #Science #Immunology, Shivangi Dave & André Ballesteros Tato at the #NIH review the noncanonical contributions of #TFollicularHelper ( #TFH ) cells cells to immune regulation beyond their traditional roles in #BCell help! science.org/doi/10.1126/sciimmunol.adr1052
🩺 Prof. Catherine Aiken sharing key insights from the MBRRACE reports on cancer in pregnancy. 📊 1 in 4,000 women is diagnosed with a new cancer during pregnancy. For most maternity units, that’s ~1–2 cases per year. #MaternalHealth #Oncology
🧠 IFNγ alters the immuno-/proteasome, thus glycolysis surges, oxidation rises, and axons die in models of MS. Blocking the proteasome swap or glycolysis saves nerves. Impressive work by our esteemed colleague @manuelfriese.bsky.social in @cp-cell.bsky.social: doi.org/10.1016/j.ce... 🧪
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis
Inflammation, aberrant proteostasis, and energy depletion are hallmarks of neurodegenerative diseases such as multiple sclerosis (MS). However, the in…
doi.org
It’s #EULAR2025 week! 🌟 We’ve got a EULAR sandwich 🥪 this year with me presenting on type I interferon signalling in cSLE on Wednesday afternoon (4.30-6pm, room 6.4), then @heather--cross.bsky.social presenting on sex hormones and cSLE risk on Saturday (12-1.15pm, room A1) See you in Barcelona! 🇪🇸
George Robinson@georgearobinson.bsky.social · last yr.Proud moment last week with first major conference oral presentation abstract accepted for PhD student Heather Cross #EULAR2025! Also my first PI/student double bill! Bring on Barcelona! @arrdept-ucldom.bsky.social
Made it! #EULAR2025 I’m looking forward to presenting later today on a novel approach to investigating type I interferon signalling in cSLE. Interrogating different signalling levels gives unique pieces of information and new disease endotypes. Hopefully see you there to hear more!
Inspiring talk from the amazing Jess Manson! 🙌 @jury-lab.bsky.social
George Robinson@georgearobinson.bsky.social · last yr.Other @arrdept-ucldom.bsky.social highlights from our amazing @jury-lab.bsky.social HLH Team including: ⭐ Jess Manson (MAS, Thurs, 1.30-4.45pm, room 6.3) ⭐ Lexie Oppong (POS0716) ⭐ Amelia Holloway (POS0442) Also Maria Leandro POS1238 and talk/meet the expert from @anisurrahman.bsky.social #EULAR2025
👋Welcome from the PAED Community. Join us at #EULAR2025 in Barcelona! Discover breakthroughs in: ✨Still’s disease in children & adults. 🌍Global care for Juvenile Idiopathic Arthritis. 🎓Managing childhood lupus. Learn more 👉 https://pulse.ly/r8vog3jfnx #eularPAED #Rheumatology
Posters all about our #HLH research on now #EULAR @arrdept-ucldom.bsky.social
George Robinson@georgearobinson.bsky.social · last yr.Other @arrdept-ucldom.bsky.social highlights from our amazing @jury-lab.bsky.social HLH Team including: ⭐ Jess Manson (MAS, Thurs, 1.30-4.45pm, room 6.3) ⭐ Lexie Oppong (POS0716) ⭐ Amelia Holloway (POS0442) Also Maria Leandro POS1238 and talk/meet the expert from @anisurrahman.bsky.social #EULAR2025
It's time for our next ARR dept research spotlight💡with 1st year PhD student @heather--cross.bsky.social! Heather is working in @georgearobinson.bsky.social's lab with @ciurtinlab.bsky.social to uncover the impact of sex and gender ⚧️ on metabolism and its relevance to autoimmune conditions💥
That looks worrying!!
UCL Dept of Aging, Rheumatology & Regenerative Medicine@arrdept-ucldom.bsky.social · last yr.When she's not in the lab @heather--cross.bsky.social is baking, cooking and hanging upside down in an aerial hammock! Something to talk to her about (alongside science ofc!) when you see her at EULAR!
Enjoy #EULAR @heather--cross.bsky.social great opportunity to present your exciting work on sex hormones and immunity
UCL Dept of Aging, Rheumatology & Regenerative Medicine@arrdept-ucldom.bsky.social · last yr.If you want to hear about @heather--cross.bsky.social findings you can catch her at #EULAR where she giving a talk in the 'how does sex and gender predispose to autoimmunity?' session winning a travel grant 💫 Check her out with her poster at our recent Division of Medicine Research Retreat below👇
