🚨 IT’S FINALLY HERE #2026SDB starts TODAY! 🧬🎰 The countdown is over, and it’s time for the developmental biology community to come together in Las Vegas! Get ready for exciting science, new ideas, and plenty of opportunities to connect. See you at #2026SDB! 🎉

This is bizarre! tl;dr Female carp germline stem cells were transplanted into #zebrafish. The cells were able to adapt to the zebrafish host, differentiate into grass carp–derived sperm within just three months & were capable of successful fertilization: producing all-female grass carp offspring! 🧪

Science China Press@sciencechinapress.bsky.social · 3mo ago

Tiny zebrafish, huge impact: Grass carp reproduction accelerated 20-fold Here, researchers report in Science China Life Sciences with a cover story of an ultra-fast surrogate reproduction strategy: www.eurekalert.org/news-release... #LifeSciences #Biology #StemCells #Zebrafish #Aquaculture

Doing the periodic cleaning of used plasmid miniprep columns and realized in honor of Earth Day it may be worth reminding you molecular biologists: Plasmid miniprep columns can be cleaned and reused essentially indefinitely! Just add 1 M HCl, soak overnight and wash 3x w/ water. Save $ and plastic

I’m excited to announce that after the conclusion of my postbac at the NICHD, I will be pursuing my PhD at @uwmadison.bsky.social in their CMB Program. I'm excited for this opportunity, and very grateful for my past and current mentors for giving me the skills and support to make this possible.

How do funding decisions shape the direction of biomedical research? Can we spot transformative discoveries years before they are recognised by prizes, policies, or the wider community? Watch the #spotLights discussion feat. @kawillis.bsky.social & @jontytownson.bsky.social youtu.be/u-X3dYl7dHQ?...

spotLights Ep 19: preLights in conversation with Kristine Willis

YouTube video by The Company of Biologists

youtu.be

I am proud to have contributed to this project during the first part of my postbaccalaureate fellowship, and excited to spend the rest of my time in this lab further investigating this structure.

Dan 🐟 C@zebrafish007.bsky.social · 9mo ago

Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park! “Specialized gas-exchange endothelium of the zebrafish gill” — www.biorxiv.org/content/10.6... Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)

Genetic gatekeepers of gametogenesis? TET proteins jointly jam germline specification, synergistically steering cells towards somatic fates. @justingutbio.bsky.social's new #preLight talks about the work of @r-pantier.bsky.social and the team. Have a look!

TET knockout cells transit between pluripotent states and exhibit precocious germline entry - preLights

Genetic gatekeepers of gametogenesis? TET proteins jointly jam germline specification, synergistically steering cells towards somatic fates.

prelights.biologists.com

Excited to announce I recently highlighted another preprint for @prelights.bsky.social. In this preprint, @r-pantier.bsky.social and co-authors from the Chambers Lab at the University of Edinburgh find that the TET proteins act together to help mammalian cells specify into somatic lineages.

TET knockout cells transit between pluripotent states and exhibit precocious germline entry - preLights

Genetic gatekeepers of gametogenesis? TET proteins jointly jam germline specification, synergistically steering cells towards somatic fates.

prelights.biologists.com

Excited to announce that a new protocol to test potential PD-1/PD-L1 inhibitors was recently published by my former lab at URI. I’m happy to have contributed to this method to determine drug candidates’ ability to block this pathway, commonly exploited by cancer cells to hide from the immune system.

A new call to revise the limit to culture human embryos, currently not allowed beyond 14 days (start of gastrulation) to 28 days www.nature.com/articles/d41.... There is no new argument here to add to earlier calls but, as often in this argument, certain caveats are glossed over….. . 🧵

Human embryo research: how to move towards a 28-day limit

The decades-old limit on how long human embryos can be grown in culture is under debate. A new road map outlines how to extend the length of culture responsibly.

nature.com

The decades-old limit on how long human embryos can be grown in culture is under debate https://go.nature.com/448yuYw

Human embryo research: how to move towards a 28-day limit

The decades-old limit on how long human embryos can be grown in culture is under debate. A new road map outlines how to extend the length of culture responsibly.

go.nature.com

In a follow-up to our recent coverage of the NIH, our latest piece talks about the NSF’s role in funding basic science in the U.S. and how that role is being threatened by restructuring, budget cuts, and cuts to training programs and fellowships like REUs and the GRFP. Read about it here: 🧪 #scicomm

How We Talk About Science@howwetalkabtsci.bsky.social · last yr.

The NIH isn’t the only federal agency that funds U.S. science, and it isn’t the only agency imperiled by political interference, either. Read our latest on the National Science Foundation and what we stand to lose if cuts to funding and training programs continue: open.substack.com/pub/isabella...

What does real inclusion look like in biology? 🌈 Join Dr. Katelyn Cooper, Associate Professor at Arizona State University, on June 18 for a free webinar: Inclusive Illusions: LGBTQ+ Realities in the Biological Sciences 🔗 www.ascb.org/ascb.../incl... #STEMdiversity #LGBTQinSTEM #ASCB #CellBiology

Inclusive Illusions: LGBTQ+ Realities in the Biological Sciences - ASCB

Discover key findings from the largest survey on LGBTQ+ experiences in biology in this webinar led by ASCB’s LGBTQ+ Committee and partner societies.

ascb.org

A great highlight of some really important research. It reminds me of another article I read a few months ago from @ascbiology.bsky.social about how open you should be with your identity when applying to academic jobs (www.ascb.org/diversity-eq...). All three works are definitely worth reading.

Coming Out—Before, During, or After Getting a New Job? - ASCB

Three members of the ASCB LGBTQ+ Committee who have recently obtained Assistant Professor positions at major U.S. universities share their perspectives on navigating their LGBTQ+ identities in applica...

ascb.org

preLights@prelights.bsky.social · last yr.

Who “belongs” in biology? The first comprehensive analysis of the LGBTQ+ climate in the biological sciences! #LGBTinSTEM #preprint 🏳️‍🌈 #preLight prepared by @ryanharrison13.bsky.social, Stefan & @reinierprosee.bsky.social ⬇️👀 prelights.biologists.com/highlights/l...

Who “belongs” in biology? The first comprehensive analysis of the LGBTQ+ climate in the biological sciences! #LGBTinSTEM #preprint 🏳️‍🌈 #preLight prepared by @ryanharrison13.bsky.social, Stefan & @reinierprosee.bsky.social ⬇️👀 prelights.biologists.com/highlights/l...

LGBTQ+ realities in the biological sciences - preLights

Who “belongs” in biology? Researchers conduct the first comprehensive analysis of the LGBTQ+ climate in biological sciences.

prelights.biologists.com

Happy Pride Month, shoalmates! 🏳️‍🌈 🏳️‍⚧️🐟 Our own Danny-O the #zebrafish is rockin’ the rainbow guitar this month 💪 #NewProfilePic

Choking under pressure? 🥵 3D confinement in hydrogel-based culture inhibits muscle stem cell activation and differentiation. “…this #preprint demonstrates the interconnectedness of different subfields of biology.” #preLight of @justingutbio.bsky.social ⬇️👀 prelights.biologists.com/highlights/3...

3D mechanical confinement directs muscle stem cell fate and function - preLights

Choking under pressure? 3D confinement in hydrogel-based culture inhibits muscle stem cell activation and differentiation

prelights.biologists.com

Excited to announce I just posted a new preLight showcasing the work of @thegaaa.bsky.social in the lab of @thewooj.bsky.social on the effects of 3D confinement on muscle stem cell proliferation and differentiation using an asymmetric hydrogel bilayer model. Check out the post and their paper below:

In this very cool 1-2 punch from the Weinstein lab, start by reading Miranda & co’s awesome pre-print about a novel epigenetic reporter and follow it up with @jimmykjm.bsky.social’s pre-print using it to characterize epigenetic reprogramming during fin regeneration: www.biorxiv.org/content/10.1...

Miranda Marvel@mmarvel.bsky.social · last yr.

It's been a long time coming and I'm super excited to share our new preprint is out: "A novel transgenic reporter to study vertebrate epigenetics". We generated a zebrafish epigenetic reporter and found a fatty liver disease mutant with weird epigenetic phenotypes 👇 www.biorxiv.org/content/10.1...

preLights in developmental biology (February 2025) This article lists the recent posts @prelights.bsky.social that discuss #preprints in #DevBio and #StemCells. Featured #preLight by @justingutbio.bsky.social, covering a #preprint on germplasm stability from the lab of @reneketting.bsky.social.

preLights in developmental biology (February 2025)

This article includes recent preLights posts that discuss preprints in the field of developmental and stem cell biology.Germplasm stability in zebrafish requires maternal Tdrd6a and Tdrd6c by Alessand...

journals.biologists.com

Excited to announce I joined @prelights.bsky.social and wrote my first post for them! Looking forward to covering more cool science in the future.

preLights@prelights.bsky.social · 2y ago

Maternally deposited proteins Tdrd6a & Tdrd6c regulate Bucky ball activity and ensure the retention of germplasm in zebrafish embryos. 🐟 @justingutbio.bsky.social covers a #preprint from the lab of @reneketting.bsky.social Take a look at the #preLight! ⬇️👀 prelights.biologists.com/highlights/g...