NY state friends, please do this today! The Governor’s State of the State is tomorrow, January 13 at 1:00 PM. We are hopeful she will announce the Empire Biomedical Research Institute (EBRI). Email the Governor and your Reps! actionnetwork.org/letters/supp...

Support the Empire Biomedical Research Institute (EBRI)

Tell New York Governor Hochul and your state legislators to support including the Empire Biomedical Research Institute in the 2027 Executive Budget. This is an urgent matter relating to funding life-s...

actionnetwork.org

NY-CURES@nycures.bsky.social · 8mo ago

📢 SIGN & SHARE THE PETITION! 📢 New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW

Starting off the year with a glorious encounter between two Brazilian screen queens: Fernanda Montenegro, the unforgettable star of CENTRAL STATION, meets Kleber Mendonça Filho discovery Tânia Maria, a pistol in THE SECRET AGENT as Dona Sebastiana. Love this so much.

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/

Excited to head to Japan in November to present at the CSHA meeting on Immunoreceptor Signaling and Therapeutic Applications. Abstract deadline is next week! www.csh-asia.org?content/1343

It was a privilege and a pleasure for both myself and @menezesnmaria.bsky.social‬ to preview a great upcoming article in @cp-immunity.bsky.social‬ by @kamphorstlab.bsky.social‬ showing an unexpected inhibitory role for ICOS in exhausted CD8+ T cells. www.cell.com/immunity/abs...

The high (I)COSt of costimulation for exhausted T cells

ICOS agonists are being investigated for cancer immunotherapy based on the idea that they will reinvigorate exhausted CD8+ T cell anti-cancer immunity. Humblin et al. unexpectedly find the opposite—th...

cell.com

BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds.   How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?  Trump must end this illegal funding freeze.

Hopefully a nudge in the right direction thehill.com/homenews/543...

NIH broke law by withholding funding: GAO

A congressional watchdog determined Tuesday that the Trump administration broke the law when it directed the National Institutes of Health (NIH) to cancel hundreds of research grants earlier this y…

thehill.com

Our paper is out! Check out this beautiful story where we uncovered that the costimulatory molecule ICOS is detrimental for PD-1+ CD8 T cells. Sustained ICOS signaling reduces memory-like features of progenitor exhausted CD8 T cells in chronic viral infection and liver cancer.

The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

Understanding regulation of progenitor exhausted CD8+ T (Tpex) cell differentiation is important for immunotherapies. Humblin et al. report that sustained ICOS costimulation is detrimental to PD-1+CD8...

urldefense.proofpoint.com

Waggoner Lab@labwaggoner.bsky.social · last yr.

The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells @cp-immunity.bsky.social @kamphorstlab.bsky.social www.cell.com/immunity/ful...

These are extremely challenging times for early-career faculty. Here is my office's small contribution to make their hard and important work a bit easier: Download our curated and comprehensive database of funding opportunities for early-career faculty. Here: research.jhu.edu/rdt/funding-...

By itself, this is certainly not the most important issue we're confronting right now. But it's emblematic of the pervasive, destructive, anti-science efforts. Gift link www.nytimes.com/2025/02/26/c...

She Lobbied for a Carcinogen. Now She’s at the E.P.A., Approving New Chemicals. (Gift Article)

Lynn Dekleva, who recently took a senior role at the agency, once led an aggressive effort by industry to block regulations on formaldehyde.

nytimes.com

I am sure a lot more science programs will have to make these tough decisions

Alt NIH Bluesky 🧪@altnih4science.bsky.social · last yr.

BREAKING: The NIH summer internship program (SIP) has been officially cancelled, across all institutes. It’s a sad loss for the brightest science students in America, for American science, and for future cures for diseases like cancer and Alzheimer’s. 🧪 1/

'In 2024, a budget cut of €900m shocked the scientific community. More recently, additional amendments to this budget proposed further cuts of €630m, along with an extra €534m reduction to the France 2030 program. These cuts threaten not only basic research but also higher education'

The importance of delivering Recherche d'Avenir – research for the future

In recent years, several European countries, including France, have reduced their investment in scientific research, with biomedical research taking a significant hit. The primary casualty is basic re...

journals.biologists.com

We are too! DM me or find me on Signal at zacharybrennan.20

Jeremy Berg@jeremymberg.bsky.social · last yr.

ATTENTION The Washington Post is collecting data about funding issues. Please consider contributing. thewashingtonpost.formstack.com/forms/scient...

Donald Trump and Elon Musk’s idea of efficiency is stopping research on curing cancer.

March is still a long time from now. We need to stop the bleeding. Talk to your patients. Reach out to your patient advocates and community scientist - call your representatives! Make some noise.

Stand Up for Science!@standupforscience.net · last yr.

We want you to help us #standupforscience2025 📣 We’re currently recruiting local leads and volunteers across all state capitals and other major cities across the US! If you’re interested in helping us organize, please fill out this form: airtable.com/app4h5wUssMG...

Use this form to tell us how the new US administration is affecting your research, or suggest future coverage https://go.nature.com/42SyoUu

Are the Trump team’s actions affecting your research? How to contact Nature

Use this form to share information with Nature’s news team, or to make suggestions for future coverage.

go.nature.com

In my lab, we analyze patient samples and develop preclinical models to understand why some patients respond to immunotherpies and others don't. We write grants to support our research. Only 9%, really the top, are funded. But now, NCI/NIH tare not awarding grants even to top scores.

Stand Up for Science!@standupforscience.net · last yr.

Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence

Internal NIH guidance updated yesterday. Just canceling stuff each day from here on out I guess, pending new guidance. Killing science off both slowly and incredibly rapidly.

ATTENTION If anyone has received a NoA after the "pause", please DM me with information about the mechanism and institute or center. THANK YOU

a cartoon character says " just let me know "

ALT: a cartoon character says " just let me know "

media.tenor.com

The deadline to submit an abstract for a poster presentation is Feb 20. Register now 👉 hubs.la/Q034zC0H0 #KSCancerImmune25

So the first year of one our #NIH grants ended on 1/31 and we have not received the Notice of Award for year 2. I'm so confused now--is there an NIH freeze or not? Wasn't it blocked by a judge? Has anyone else received a NOA since this debacle? #academicsky #medsky

Absolutely. Dozens of them. See also www.chronicle.com/article/were...

‘We’re Being Punished’: NIH Tosses Some Grant Applications From Minority Researchers

The sudden withdrawal affects early-career scholars who applied for a prestigious federal grant with a diversity notation — flagging that they came from underrepresented backgrounds.

chronicle.com

Austin Robinson@ausrob-phd.bsky.social · last yr.

Hi Jeremy, have you received confirmation that the diversity F31s submitted in the fall were indeed removed from review for the study section? I saw many people sharing the anonymous post earlier this week, but have you received correspondence from someone this happened to?

Press release by the appropriations subcommittee on NIH budget slashing by @delauro.house.gov 🙏

Trump Team Dismantles Efforts to Find a Cure for Cancer and Other Deadly Disorders and Diseases

President Trump’s Administration is imposing a new policy to cap indirect costs for National Institutes of Health (NIH) research grants at 15 percent, which would cut billions of dollars in funding fo...

democrats-appropriations.house.gov

awful

Marion Pepper@marionpepper.bsky.social · last yr.

@jeremymberg.bsky.social Have you or anyone else heard about any Admin supplements to Promote Research Continuity (“Maternity Leave Supplements”) being discontinued? A new Asst. Prof. at home with a tiny baby just had hers disappear from her ERA commons account while waiting for her NOA. Awful.

YES. Need to say this loudly and often! This 2.46x is also the short-term ROI. Long-term ROI (more difficult to estimate) may ~10x. Highest for any gov't spending. And the source of discoveries necessary for all new drugs (industry important too but without NIH funded science there's no foundation)

Jonathan Kagan@jkagan1.bsky.social · last yr.

www.fiercebiotech.com/research/rep...

First time calling politicians - it felt GOOD! Empowering - might call them again tomorrow, and the day after - get out there! this 5calls website will tell you who to call and provide a draft script #science will #prevail. 5calls.org/issue/nih-ns...

Save NIH and NSF Research Funding ⭑ 5 Calls

On February 7, the Trump administration moved to cut billions of dollars in funding from the National Institutes of Health (NIH) and National Science …

5calls.org

The loss of AMERICAN science will have ripple effects on jobs and economic growth. At the same time China and other countries are investing heavily in science @schumer.senate.gov @nadler.house.gov

Carl T. Bergstrom@carlbergstrom.com · last yr.

The NIH overhead cut doesn't just hurt universities. It's deadly to the US economy. The US is a world leader in tech due to the ecosystem that NIH and NSF propel. It drives innovation for tech transfer, creates a highly-skilled sci/tech workforce, and fosters academic/industry crossfertilization.

@altnih4science.bsky.social Are study sections and council meetings happening at NIH this week?

Extremely disappointed to see HHMI decide to kill their Inclusive Excellence program, including terminating the current IE3 awards to over a hundred institutions effective this year in the middle of a 6-year grant. I was hoping HHMI (and other private funders) would continue to lead the way.

NIH website down. 😱