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Karen Lange

@karenphd.bsky.social

C. elegans, cilia, ciliopathies, CRISPR. Researcher/PI at University College Dublin, Ireland.

90 Posts659 Follower739 Folgt
Addgene@addgene.bsky.social · 2w ago

Are you working with C. elegans? 🪱 Check out our updated Worm Collection page, now including tables for biosensors and reporters, codon-optimized, genome engineering, and neuroscience plasmids! Browse the Worm Collection here:

Addgene: Worm Plasmids and Resources

Browse Addgene’s collection of plasmid tools, kits, and resources for use in C. elegans research. Including genome engineering, codon-optimized, biosensors and reporters, and neuroscience plasmids.

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Meera Sundaram@meera-sundaram.bsky.social · 2mo ago

Can Alphafold help predict protein-protein interactions in the #aECM? Our initial results seem promising! www.biorxiv.org/content/10.6...

A Lipocalin and a Hedgehog-related protein are partners in the C. elegans pre-cuticle apical extracellular matrix

Apical extracellular matrices (aECMs) line exposed body surfaces to shape tissues and protect them from the environment. These aECMs often organize into complex patterns and structures, but how such m...

biorxiv.org

Maureen Barr@barrlab.bsky.social · 2mo ago

Really excited about our new paper. The 2nd author Carlos Nava Cruz started as an UG, was supported by an diversity NIH supplement, & is completing his masters. C. elegans model for functional analysis of conserved ADPKD variants in cilia, EVs, & signaling academic.oup.com/genetics/art...

A C. elegans model for functional analysis of conserved ADPKD variants in cilia, extracellular vesicles, and sensory signaling

Abstract. Interpreting the pathogenic significance of missense variants in human disease gene candidates remains a major challenge in precision medicine. A

academic.oup.com

Javier Apfeld@javierapfeld.bsky.social · 3mo ago

Do you want to support the next generation of C. elegans researchers? We are looking for mentors with C. elegans experience, including postdocs, faculty, and scientists outside academia, to share their knowledge and career advice with early career researchers. Sign up to become a mentor!

Mentor sign-up for the C. elegans Community Mentor Match program - 2026

Thanks for volunteering to be a Mentor! The 2026 cycle of the C. elegans Community Mentor Match is open to graduate students, postdocs and faculty at any career stage. This survey collects information...

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Thiago Carvalho@cyrilpedia.bsky.social · 4mo ago

'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.' link.springer.com/article/10.1...

The controls that got out of control - EMBO Reports

EMBO Reports - When experimental controls go wrong, it does not necessarily mean your experiment is flawed. It might well be the first sign of something unexpected.

link.springer.com