🚨 Preprint alert! 🚨 How does the olfactory bulb transform overlapping sensory inputs into representations that are easier to distinguish? New study by Sina Tootoonian, Yikai Yang, @andreas-t-schaefer.bsky.social @crick.ac.uk and myself.‬ www.biorxiv.org/content/10.6... A short 🧵 below

Join us as we explore where optogenetics is headed next at #OptoGRC2026 ⚡ With Megha Sehgal, Nicolo Accanto, @flaviodonato82.bsky.social, @logangrosenick.bsky.social, @sydneytrask.bsky.social, Hoda Shamsnajafabadi & Susoban Das 💡

An opportunity to work with a truly brilliant mentor on exciting questions using really cool techniques. Highly recommended!!

Antoine Bergel@antbergel.bsky.social · 4mo ago

⚠️ Postdoc Opportunity in System Neuroscience at the Paris Brain Institute ⚠️ Feel passionate about neuroscience and sleep 🧠? Want to learn cutting-edge techniques 🔬 to answer exciting basic science questions? Want to work in a multidisciplinary environment at the heart of Paris 🏨? Come join us !

Thrilled to see our paper published! I’m deeply grateful to the amazing @ggirardeau.bsky.social for trusting me to develop and carry it out. Many thanks as well to @azulsilva.bsky.social , @belalima-paiva.bsky.social and Eleonore for driving this work forward together. www.nature.com/articles/s41...

Dorsoventral hippocampus neural assemblies reactivate during sleep following an aversive experience - Nature Neuroscience

Synchronization of sharp-wave ripples across the dorsoventral hippocampus during sleep supports coordinated reactivation that represents negative experiences more faithfully than positive ones.

nature.com

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

Edvard I Moser@edvardmoser.bsky.social · 5mo ago

Is spatial navigation innate 🧠? Using #NeuroPixels we show that the #torus 🍩 underlying the #GridCell map exists already on day 10 in rats — before pups open eyes and ears and before they start upright walking. 🧵1:4 👇 www.biorxiv.org/content/10.6...

Happy belated publication of some of my PhD work! Building on our findings that grid field firing rate changes can cause hippocampal remapping and memory impairment, here we show that this effect has a fixed input-output relationship, and we can even predict how place cells will remap!

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 6mo ago

Reproducible and predictable reorganization of place fields driven by grid subfield rate changes https://www.biorxiv.org/content/10.64898/2026.02.10.705142v1

One ring to rule them all….

Adrien Peyrache@apeyrache.bsky.social · 6mo ago

New paper alert! 🚨 We found that the brain's compass is remarkably stable at two scales 1️⃣ the system maintains its internal organization for weeks 2️⃣ It "remembers" its orientation for weeks, even after a single visit This may be key to how the brain aligns its other maps. Paper: rdcu.be/e3waP

We had a lot of fun doing these experiments! Theta sweeps in MEC and internal direction signals in parasubiculum track moving objects during pursuit and reverse during backward movement. Simultaneously recorded HD cells in other areas remain locked to head direction across behaviors:

Edvard I Moser@edvardmoser.bsky.social · 6mo ago

The hippocampal map has its own attentional control signal! Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See 📹 in post 4/6 and preprint here 👉 www.biorxiv.org/content/10.6... 🧵(1/6)

Postdoc position in systems neuroscience! Excited to recruit a postdoc for my lab at the University of Bonn. 🔬 In vivo physiology (Neuropixels, 2P/miniscope) 🐭 Head-fixed & freely moving behaviour 💡 Optogenetics/chemogenetics ⏳ Start: ASAP | Application deadline: 28.02.2026 More info below ⬇️

⚠️ New paper alert and what a way to end 2025! 🎉 Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience. Sleeping dragons 🦎 and functional ultrasound! Read the full paper here: rdcu.be/eWJHb 1/8

Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals

Nature Neuroscience - Bergel et al. show that an infraslow rhythm connecting the brain and body during sleep is shared by lizards, mammals and birds, revealing an ancestral process and reshaping...

rdcu.be

Looking for a postdoc to understand dynamic vision in action in freely moving mice? Get in touch! This is a @erc.europa.eu postdoc in a project between us and @sinzlab.bsky.social: miniature 2-photon, rich behavior tracking, and deep learning models linking natural behavior to cortical activity|RT

Fabian Sinz@sinzlab.bsky.social · 9mo ago

🔬 Exciting PostDoc Opportunity! 🐁🧠 We - the @sinzlab.bsky.social (sinzlab.org) and @trose-neuro.bsky.social (troselab.de) Labs - are seeking an experimental postdoc to work at @unibonn.bsky.social with cutting-edge miniature 2-photon microscopy and gaze tracking in freely behaving mice.

The Sosa Lab is going to #SfN25 and actively recruiting ✨postdocs✨ with systems neuroscience experience! We study both fundamental memory processes and how memory changes during pregnancy and postpartum. If you are interested in meeting at SfN, please email me! www.sosaneurolab.com/join/postdoc...

Sosa Lab - Postdoctoral Researchers

We are seeking postdocs to start in 2026!

sosaneurolab.com

Come do a postdoc at the Wu Tsai Institute! WTI fellows have freedom to work with anyone at the institute, and preference is given to applicants who want to work on interdisciplinary projects with multiple faculty mentors. If you’re interested to work with me, please reach out!

Wu Tsai Institute | Yale University@wutsaiyale.bsky.social · 10mo ago

📣 Calling experimental, computational, or theoretical researchers! WTI's Postdoc Fellowships application is now open, offering a competitive salary, structured mentorship, world-class facilities + more: wti.yale.edu/initiatives/... Apply by November 10: apply.interfolio.com/174525 #KnowTogether

Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)

The postsubiculum as a head-direction cortex

The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…

sciencedirect.com

The Sosa Lab website is now live! www.sosaneurolab.com We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.

Sosa Lab

sosaneurolab.com

Stoked to see this paper finally out! It answers two big questions: where visual objects are encoded in the brain, and how head-direction cells get oriented using visual landmarks. Super fun collaboration with @mace-lab.bsky.social and Stuart Trenholm. www.science.org/doi/10.1126/...

Visual objects refine head direction coding

Animals use visual objects to guide navigation-related behaviors. However, visual object–preferring areas have yet to be described in the mouse brain, limiting our understanding of how visual objects ...

science.org

Emilie Macé@mace-lab.bsky.social · 11mo ago

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

📣 We are expanding! Repost 🙏🏽 - Postdoc (funded by @simonsfoundation.org grant on synchronisation between cognitive representations and stepping) - Project Associates - Create your role! (Reach out if you are keen on these topics and these roles do not define you 👀🤗) www.neuroact.in

Thrilled to announce I'll be starting my own neuro-theory lab, as an Assistant Professor at @yaleneuro.bsky.social @wutsaiyale.bsky.social this Fall! My group will study offline learning in the sleeping brain: how neural activity self-organizes during sleep and the computations it performs. 🧵

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇

Event structure sculpts neural population dynamics in the lateral entorhinal cortex

Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...

science.org

Edvard I Moser@edvardmoser.bsky.social · last yr.

Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...

#neuroskyence folks: as my postdoc grant is running out soon, I am looking for new opportunities in systems neuroscience! Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia. Sharing appreciated, and happy #FluorescenceFriday !

I joined this podcast to talk about sleep, dreams, and James Joyce. Yes, all in one conversation. It was a lot of fun! 🔊 Heads up: the audio is a bit rough at the start, but it clears up quickly. Listen here: podcasts.apple.com/ca/podcast/b...

Bonus: Professors Adrien Peyrache and Arjun Krishnaswamy on Wake and the Sleeping Brain

Podcast Episode · WAKE: Cold Reading Finnegans Wake · 2025-03-26 · 1h 11m

podcasts.apple.com

Excited to share the sequel to our 2022 paper! In this follow-up, we show that the stable head direction (HD) signals we reported in blind mice rely on stereo olfaction—that is, the comparison of odor info. between the two nostrils. Link: www.nature.com/articles/s41... 🧵highlights below

Stereo olfaction underlies stable coding of head direction in blind mice - Nature Communications

Stereo olfaction involves comparing odor differences between the two nostrils. Here, using neuronal recordings and a behavioral test, the authors demonstrate that blind mice use stereo olfaction to fo...

nature.com

Check out Amy’s cool work on the octopus visual system! Amy + team describe novel receptors and map their distribution and function in the optical lobe. Turns out: Octos run different hardware to process visual input, but might have evolved similar circuit motives / logic to those in vertebrates!

Amy Courtney@amycourtneyyy.bsky.social · last yr.

Very excited and proud to finally share this story! 🐙 We discovered surprising roles for dopamine and acetylcholine in the Octopus visual system… doi.org/10.1101/2025...

delighted to share our work revealing a new type of excitatory hippocampal neuron we call the "ovoid cell", which has really exquisite properties relative to adjacent pyramidal cells! superb work of first-author @adriennekinman.bsky.social and many others in the lab www.nature.com/articles/s41...

Atypical hippocampal excitatory neurons express and govern object memory - Nature Communications

Pyramidal cells are classically thought to comprise the excitatory output of the subiculum. Here, the authors show the existence of “ovoid cells”, excitatory subiculum neurons with specialized gene ex...

nature.com