Our latest article examines the sulfonamide resistance gene sul4. By using long-read metagenomics and methylation patterns, we show that sul4 appears in diverse genetic contexts and hosts, expanding our understanding of its environmental distribution. doi.org/10.1128/spec... #AntibioticResistance

Sulfonamide resistance gene sul4 is hosted by common wastewater sludge bacteria and found in various newly described contexts and hosts | Microbiology Spectrum

Antibiotic resistance is an ancient phenomenon and a common trait of many environmental bacteria. However, human activities in the post-antibiotic era, coupled with the bacteria’s ability to exchange ...

doi.org

The Relationship Between Gut Microbiota During Pregnancy and the Level of Postpartum Adiposity - Houttu - 2025 - MicrobiologyOpen - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...

The Relationship Between Gut Microbiota During Pregnancy and the Level of Postpartum Adiposity

Postpartum adiposity is associated with maternal α-diversity and several bacterial species. These findings highlight the mediating role of the gut microbiota during pregnancy in influencing the overw...

onlinelibrary.wiley.com

Using wastewater surveillance to investigate community-level differences in antibacterial resistance in a major urban center, USA | Applied and Environmental Microbiology journals-asm-org.ezproxy.utu.fi:2443/doi/10.1128/...

And it is (finally) accepted to be published in Microbiology Spectrum.

Antti Karkman@anttikarkman.bsky.social · 2y ago

Our work on the sulfonamide resistance gene, sul4, is (finally) available as preprint. Thanks to an excellent PhD student Melina Markkanen. Hopefully soon it will be also peer-reviewed and published. After the first desk rejection, we are looking for another journal. doi.org/10.1101/2025...

Nice paper on the temporal dynamics of early infancy. Once again, it was shown that Escherichia & Klebsiella correlate with higher ARG load, and their abundance is in turn negatively associated with Bifidos. Kudos to the authors for the excellent paper! rdcu.be/eDRPa

Temporal dynamics and microbial interactions shaping the gut resistome in early infancy

Nature Communications - Here the authors show that antibiotic resistance genes peak in the gut at the age of 6 months, and that beneficial bifidobacteria produce aromatic lactic acids that actively...

rdcu.be

Proud of our group's newest publication!

Mike Inouye@mikeinouye.bsky.social · last yr.

Variation and prognostic potential of the gut antibiotic resistome in a population-based cohort www.nature.com/articles/s41... We look at the risks and sociodemographic aspects of antimicrobial resistance, and its association with recent global urbanization and middle-class growth.

Great thread from @antagomir.bsky.social about our latest collaborative study led by the brilliant @katammp.bsky.social on the antibiotic resistome in a representative Finnish population of n>6,500 individuals and factors associated with carriage. Link to study: doi.org/10.1038/s414...

Variation and prognostic potential of the gut antibiotic resistome in the FINRISK 2002 cohort - Nature Communications

Here, in a representative cohort of 7,095 Finnish adults, the authors reveal that gut antibiotic resistance is shaped not only by antibiotic use but also by the microbiome, diet, lifestyle, household ...

doi.org

Leo Lahti@antagomir.bsky.social · last yr.

Antimicrobial resistance ( #AMR ) is a silent pandemic that has been attributed to over a million deaths per year worldwide. Socio-demographic factors contribute to the emergence and spread of AMR.🧵

Read the study: doi.org/10.1038/s414... - /w @katammp.bsky.social @begia.bsky.social Guilhem Sommeria-Klein, Ville Laitinen, Pyry Kantanen, @gmeric.bsky.social @gazollavolpiano.bsky.social Michael Inouye, Rob Knight, Veikko Salomaa, Aki S. Havulinna, Teemu Niiranen, @antagomir.bsky.social

Variation and prognostic potential of the gut antibiotic resistome in the FINRISK 2002 cohort - Nature Communications

Here, in a representative cohort of 7,095 Finnish adults, the authors reveal that gut antibiotic resistance is shaped not only by antibiotic use but also by the microbiome, diet, lifestyle, household ...

doi.org

Variation and prognostic potential of the gut antibiotic resistome in a population-based cohort www.nature.com/articles/s41... We look at the risks and sociodemographic aspects of antimicrobial resistance, and its association with recent global urbanization and middle-class growth.

Thank you #ASMicrobe 2025 for an excellent conference in Los Angeles! It was great to meet new people and present our team's recent work with #AMR

International comparison reveals gender differences in antimicrobial resistance - an analysis of more than 14,000 open gut metagenomes indicates that in high-income countries women had more antibiotic resistance than men www.utu.fi/en/news/pres... /w @katammp.bsky.social @mahkamehsalehi.bsky.social

International comparison reveals gender differences in antimicrobial resistance

A recent study led by the University of Turku, Finland, analysed the DNA map of more than 14,000 gut metagenomes in a global dataset and found that there are differences in antibiotic resistance be

utu.fi

🦠🌍 Antibiotic resistance differs by gender A global study of 14,000+ gut samples found women in high-income countries have 9% more antibiotic resistance genes than men. In lower-income countries, patterns flip – but context matters. 🔗 www.nature.com/articles/s41... #SciComm #AMR 🧪

Gender differences in global antimicrobial resistance - npj Biofilms and Microbiomes

npj Biofilms and Microbiomes - Gender differences in global antimicrobial resistance

nature.com

Kansainvälinen vertailu paljasti antibiooteille vastustuskykyisten bakteerien erot sukupuolten välillä www.utu.fi/fi/ajankohta...

Kansainvälinen vertailu paljasti antibiooteille vastustuskykyisten bakteerien erot sukupuolten välillä

Tuoreessa Turun yliopiston johtamassa tutkimuksessa analysoitiin yli 14 000 ulostemikrobiston DNA-karttaa ja havaittiin, että antibioottien vastustuskyvyssä eli resistenssissä on eroja sukupuolten

utu.fi

Take home message! Recognizing gender and age-specific differences in AMR is essential for research and for creating fair healthcare strategies. For more details, data, and code, read the full study with @katammp.bsky.social et al. here: www.nature.com/articles/s41...

Gender differences in global antimicrobial resistance - npj Biofilms and Microbiomes

npj Biofilms and Microbiomes - Gender differences in global antimicrobial resistance

nature.com

Age and geography were significant factors associated with resistome composition, with infants and the elderly showing higher ARG loads and diversity. This pattern underscores the impact of life stages on AMR.

Genders share similar ARGs despite the difference in their abundance. Region and age explained far more variation in ARG composition than gender.

Gender differences in ARG abundance emerged in adulthood, indicating that gender-associated lifestyle, biological, or healthcare-related factors in adulthood may be linked to antibiotic resistance.

In LMICs, limited data indicated that when accounting for confounding factors such as age and socio-economics, the difference between men and women was not significant.

Women in HICs also showed slightly higher ARG diversity than men, suggesting a broader range of resistance genes present in their gut microbiomes.

In high-income countries (HICs), women had 9% higher ARG abundance compared to men. This suggests that women in HICs may be more exposed to or carry more antibiotic-resistant bacteria. In low-income countries (LMICs), the trend was reversed. www.nature.com/articles/s41...

Gender differences in global antimicrobial resistance - npj Biofilms and Microbiomes

npj Biofilms and Microbiomes - Gender differences in global antimicrobial resistance

nature.com

Antimicrobial resistance #AMR is a major #globalhealth threat. How does it vary between genders? We analyzed 14,641 open human gut #metagenomes from 32 countries to investigate gender differences in #antibioticResistance genes (ARGs). www.nature.com/articles/s41...

Gender differences in global antimicrobial resistance - npj Biofilms and Microbiomes

npj Biofilms and Microbiomes - Gender differences in global antimicrobial resistance

nature.com

Did you know that the female #microbiome is unique in many ways, and antibiotic resistance in the gut microbiome varies between genders? See npj Biofilms and Microbiomes special issue, Women and their microbes, to learn more! www.nature.com/collections/...

Women and their microbes

This collection invites research on all aspects of women’s health involving the microbiome from different body sites and its interplay with fertility, ...

nature.com