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Schlundt lab

@lab-nmr.bsky.social

Group 'Analytical Biochemistry' at the Institute of Biochemistry at the University of Greifswald. We are studying protein nucleic acid interactions with a focus on NMR-based methodology.

13 Posts59 Follower43 Folgt
Magnetic Resonance News@nmr900.bsky.social · 7mo ago

Protein Science, Review, Unfolding the history of protein HDX NMR, Jordyn M. Markle, University of North Carolina at Chapel Hill onlinelibrary.wiley.com/doi/10.1002/... @proteinsociety.bsky.social #NMRchat #NMR 🧲

Unfolding the history of protein HDX NMR

I review the development of two-dimensional hydrogen-deuterium exchange (HDX) nuclear magnetic resonance (NMR) spectroscopy and highlight its importance to the study of protein structure and stabilit...

onlinelibrary.wiley.com

Schlundt lab@lab-nmr.bsky.social · 7mo ago

Congratulations to the Wöhnert lab! Should and will be highly-cited work! Worth reading! 🍾👍

Nucleic Acids Research@narjournal.bsky.social · 8mo ago

⭐NAR Breakthrough! ⭐ 🧬 A synthetic RNA forms a #G-quadruplex without a G-rich sequence, using a complex 3D fold and GTP as a ligand. This suggests G-quadruplexes may be far more widespread in biologically important RNAs. Read more: doi.org/10.1093/nar/... #NARBreaktrhough #RNA #StructuralBiology

Jonathan Lenz@geneticjonathan.bsky.social · 8mo ago

🚨Paper Alert🚨 We found a novel transcription factor function of the zinc finger protein “Hangover” in the regulation of Drosophila gene expression🪰🧬: doi.org/10.1093/nar/... #chromatin #transcription #hangover #histone modification #NSL complex A thread:

Hangover regulates gene expression by limiting NSL-mediated H4K16 acetylation

Abstract. The RNA-binding protein Hangover (Hang) is essential for several stress responses in Drosophila melanogaster. Here, we discover a novel function

doi.org

Cameron Mackereth@cdmackereth.bsky.social · 8mo ago

Our structure determination of a dopamine-binding DNA aptamer yielded surprising results. The structure had only 2 Watson-Crick base pairs, but lots of base pairs normally only seen in RNA folds. Check out our crazy DNA structure in the recent bioRxiv preprint, along with other binding details.

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bioRxiv Biochemistry@biorxiv-biochem.bsky.social · 8mo ago

Unconventional DNA architecture in a dopamine-bound aptamer complex https://www.biorxiv.org/content/10.1101/2025.11.27.690961v1

EMBO@embo.org · 10mo ago

Want to connect with researchers in #GeneRegulation, small RNAs, #StructuralBiology and more? Sign up for EMBO Workshop "RNA-guided genome protection" in Caux, Switzerland, 16–20 June 2026! Deadline: 15 March meetings.embo.org/event/26-gen... #DNAsky #RNAsky #EMBORNAGenomeProtection #EMBOevents 🧪

RNA-guided genome protection

The genome carries information across generations, ensuring species survival. To preserve faithful transmission of genetic information, RNA-directed mechanisms safeguard the genome integrity in diver…

meetings.embo.org

Schwalbe Lab@schwalbe-lab.bsky.social · last yr.

New publication in @narjournal.bsky.social - Using NMR, SAXS & MD, we characterize the dynamic nonaloop of the SARS-CoV-2 Delta s2m RNA, contributing to future ensemble-functional studies of dynamic RNA motifs. Full text: doi.org/10.1093/nar/... #RNA #StructuralBiology #NAR #NMR #MDSimulations

Structural heterogeneity and dynamics in the apical stem loop of s2m from SARS-CoV-2 Delta by an integrative NMR spectroscopy and MD simulation approach

Abstract. In structured RNAs, helical elements are often capped by apical loops that are integral structural elements, ranging from 3 to >20 nts of size

doi.org

Saganism@sagan.bsky.social · last yr.

This is from The Tonight Show with Johnny Carson aired on May 20th, 1977. Carl Sagan says something very important, a strong message that didn't lose any validity since then.