✨ Excited to host invited speaker Luisa Cochella (@lcochella.bsky.social) at #2026SDB in Las Vegas! 🎰🃏 Her research explores cell diversification and RNA-based mechanisms controlling development. 🧬✨ #devbio
Luisa Cochella
@lcochella.bsky.social
Proud worm researcher. Interested in miRNAs, all RNAs really, and gene regulation in general. A biochemist turned geneticist trying to think about questions of cell biology. Lucky to lead a lab at Johns Hopkins School of medicine. https://cochellalab.org/
The worm community has lost a true legend with the passing of Don Moerman. Don's impact on C. elegans research is beyond measure. A friend to many of us here in MN, his work has been invaluable, contributing >5,400 strains (VC & DM) to the CGC, 20% of our collection!
Come join us! This meeting is going to be awesome!
Maureen Barr@barrlab.bsky.social · 5mo agoWorm peeps: a twofer meeting in Madison! See you at the Union terrace! MAPSS + DevCell June 10-14, 2026 Joint Meeting between C. elegans Metabolism, Aging, Pathogenesis, Stress and Small RNAs & C. elegans Development Cell Biology & Gene Expression #celegans
Recurrent evolution of selfishness from an essential tRNA synthetase in Caenorhabditis tropicalis www.nature.com/articles/s41...
Recurrent evolution of selfishness from an essential tRNA synthetase in Caenorhabditis tropicalis - Nature Ecology & Evolution
In Caenorhabditis tropicalis, three toxin–antidote elements arose via gene duplication from the essential tRNA-synthetase subunit FARS-3. The ancestral antidote probably acquired affinity for FARS-3, ...
nature.com
I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n unc.peopleadmin.com/postings/307...
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group! We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology. PhD positions available!
Congrats to the winners! Its notable that Omar Yaghi was a refugee. Refugees and immigrants once again making American science great!
Nature@nature.com · 10mo agoBREAKING: The Nobel Prize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks” Stay tuned for more. #NobelPrize
It is with great sadness that we share the news of the death of our founder, colleague, mentor and friend, Professor Sir John Gurdon. His vision and dedication will continue to inspire generations of scientists. 🔗 www.gurdon.cam.ac.uk/nobel-laurea...
Staff members at the NIH seem to have done the impossible: spend the agency's $48 billion budget. “Everyone has been rallying together to clean up the mess, but it’s a mess that did not need to be made,” an NIH program officer told me. www.nature.com/articles/d41...
NIH races to spend its 2025 grant money — but fewer projects win funding
Despite political obstacles, officials are on track to disburse all of the research funds allocated to US biomedical behemoth.
nature.com
Thank you all the program officers at NIH that persisted through the 2025 fiscal year and were able to fund 99% of the total FY2024 budget. I know this has take a toll on everyone at NIH. Thank you for supporting important health and behavior science and helping to keep the U.S. a leader in science.
Jeremy Berg@jeremymberg.bsky.social · 10mo agoThe fiscal year ends tomorrow. Here are results from NIH Reporter downloaded an hour ago. The total amount of funding committed for FY2025 at this point is 99.0% of that for FY2024. The same difference could be due to a variety of technical factors. 1/3
Very excited to share this finding from my postdoctoral work that is now published in #ScienceAdvances. We show how the gut’s epithelium modifies enteric behaviors during nutritional adversity via distinct peptidergic signaling axes. www.science.org/doi/10.1126/... Thread ⬇️ (1/n)
Gut epithelium modifies enteric behaviors during nutritional adversity via distinct peptidergic signaling axes
Gut epithelium modulates output from distinct enteric circuits by altering secretion of insulin and noninsulin peptides.
science.org
Thanks for highlighting - thread to follow. Mini-summary: beyond assigning oscillatory genes expression by scRNA-seq to individual cell types, we also show that chromatin opens rhythmically and that we can predict this (and gene expression) with a small set of TFs in a mathematical model.
Max Heiman@heiman.bsky.social · 11mo agoIt accompanies a beautiful preprint from @labgrosshans.bsky.social whose pioneering work laid the foundation for the approach we took: "A scheduler for rhythmic gene expression" doi.org/10.1101/2025...
New preprint! How are developmental cycles coordinated across cell types? It turns out that, like Geppetto's cuckoo clocks in the GIF below, individual cell types are each performing their own little crazy routine, but all in sync with each other.
a bunch of clocks are hanging on a wall including one that says ' 3:00 ' on it
ALT: a bunch of clocks are hanging on a wall including one that says ' 3:00 ' on it
media.tenor.com
David Baltimore, giant of molecular biology, has died.
Matthew Cobb@matthewcobb.bsky.social · 11mo agoCo-discoverer of reverse transcriptase at 32, Nobel Prize at 37, played a key role at the 1975 Asilomar comference.
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
Our work on the function of miR-51/miR-100 is out! miR-100 is widely conserved across eumetazoans but its function has been mysterious. Emilio Santillán found in worms it regulates signaling and extracellular matrix genes, some of which seem to be conserved targets! www.science.org/doi/10.1126/...
An ancient and essential miRNA family controls cellular interaction pathways in C. elegans
A microRNA that arose at the origin of eumetazoans regulates cell adhesion and signaling in C. elegans through conserved targets.
science.org
The Argonautes 2025 - we made a special gift for participants - a card set with 32 different Argonautes + an extension pack with four Nobel prize winners from the small RNA field. Mello, Fire, Ambros & Ruvkun as jokers :-) #argonautes2025
Huge thanks to Cathy Savage-Dunn @cswormlab.bsky.social and Baris Tursun @baristursun.bsky.social for an amazing #worm25 !! I want to call out the OUTSTANDING meeting they created! Talks and posters were A+++. Most of all they brought us together in one of the most challenging times we've had.
Special thanks to Ahna Skop, Morris Maduro, and Curtis Loer for bringing so much joy to the meeting! Also, big thanks to GSA and Anne Marie Mahoney for making #worm25 happen despite the challenging times. Thank you also to USDavis for hosting us and the delicious food.
We are looking forward to the Worm Meeting 2027 and thank Suhong Xu(Zhejiang University School of Medicine, Hangzhou, China), Kavita Babu (Indian Institute of Science, Bangalore, India), and Erik Andersen (Johns Hopkins University Baltimore, USA) for organising. #worm25
Congrats to all, including Lo-Yu Chang from our lab 😁
TTina L. Gumienny@drgtwu.bsky.social · last yr.
Congrats to the winners of the #Worm25 poster competition! Thanks to all students who entered (285) — such great research! Thanks to all poster judge volunteers who judged presenters (220 postdocs and faculty!) Given >1200 attendees, that’s a high % who participated in this competition!
New paper out in @natcomms.nature.com! A surprising story of a "non-conserved" protein that's vital for human cell fitness! Fantastic work by Alexandra Shulkina in collaboration with the @lcochella.bsky.social & @clausenlab.bsky.social labs.
Our dean is taking the message to where it needs to hit. www.foxnews.com/opinion/cutt...
Cutting NIH funding isn’t how to defeat disease, it’s surrender
Plans to cut NIH funding undermine America's incredible record of medical success. Scientific research has helped win many battler against horrible diseases. We should be proud.
foxnews.com
"Funding from the NIH was contributed to 354 of 356 drugs (99.4%) approved from 2010 to 2019 totaling $187 billion" Reference: jamanetwork.com/journals/jam...
Much will be written about how 4 PhD students and a PhD –Colette Delawalla, Sam Goldstein, Emma Courtney, Leslie Berntsen & JP Flores – organized @standupforscience.bsky.social to unite scientists in the US and worldwide. Now let's keep the momentum going to defend science! bsky.app/starter-pack...
Of course times are tough, but is anyone (or does anyone know) of anyone in the DC-VA-MD area with openings for a masters-level researcher with experience in molecular biology, RNA and DNA work, transcriptomics, and specific experience with both plant and nematode genomics?
Bluetorial: The rationale for the “NIH” indirect cost “plan” is based on misunderstood (unintentional or intentional) accounting and math The value of real government transparency
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
media.tenor.com
Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence
You've waited for it, now it's finally here ... On-Demand is now available for our joint meeting on RNA Mediated Regulation of Immunity / Non-Coding RNA Biology! Purchase at keysym.us/KSRNAImmune2... or keysym.us/KSNCRNA25OD. #KSRNAImmune25 #KSNCRNA25 @skadener.bsky.social @lcochella.bsky.social
