Grosshans Lab
@labgrosshans.bsky.social
Studying mechanisms of developmental clocks and timers at the Friedrich Miescher Institute for Biomedical Research, Basel.
RNA-binding proteins (RBPs) often bind numerous transcripts - but do they act through a network effect? Our new paper in @plosbiology.org shows that the highly conserved LIN28 RBP controls developmental timing in C. elegans larvae through only two targets. doi.org/10.1371/jour... 1/n
Looking forward to joining the Doctoral Insights Symposium on 10 September and introducing students to the FMI PhD Program, our research, and life in Basel’s vibrant biomedical ecosystem 🧬
Doctoral Insights Symposium@docinsightssymp.bsky.social · 3d agoBiomedical research excellence in Basel — Novartis, Roche, and Europe's strongest biotech ecosystem next door. FMI science epigenetics, neurobiology, cell biology. Small institute, massive impact. Symposium Sept 10 → doctoralinsights.at #DocInsights #FMI #Basel
Much of the genome is made up of repetitive DNA sequences that trace back to ancient mobile elements. Two new studies from the @marcbuhler.bsky.social group, now published in @cp-molcell.bsky.social, show how cells keep these potentially disruptive sequences under control. www.fmi.ch/news-events/...
How cells keep genomic hitchhikers under control
Much of the genome is made up of repetitive DNA sequences that trace back to ancient mobile elements, many of which have lost their ability to copy themselves into new locations but can still cause pr...
fmi.ch
Undergraduate or master’s student in the life sciences looking for fully funded PhD programs in Europe? Don’t miss the free @docinsightssymp.bsky.social on Sep 10 at 14:00 CET, featuring 20+ programs across 7 countries, including the FMI International PhD Program. Register: www.doctoralinsights.at
Doctoral Insights Symposium@docinsightssymp.bsky.social · 2mo agoEuropean PhD programmes are fully funded — you're an employee with a real salary ✅ Fully funded — you're an employee ✅ International labs, English-speaking ✅ Career training built in ✅ Cities you'll love Symposium Sept 10 → doctoralinsights.at #DocInsights #PhD
We’re delighted to welcome @computingcaitie.bsky.social to the FMI next year! Her work will bring an interdisciplinary perspective spanning structural biology, quantitative imaging and computational analysis to our institute, opening exciting new ways to study ciliary structure and dynamics.
Caitie McCafferty@computingcaitie.bsky.social · last mo.Happy to finally share that I will be starting my independent group at the @fmiscience.bsky.social in Feb 2027 in a vibrant new environment. We will use integrative in situ structural cell biology methods to investigate ciliary structure and dynamics in several model (and non-model 👀) systems!!
Congratulations to FMI senior group leader Jeff Chao and his team for being awarded €2.5 million through the @erc.europa.eu Advanced Grant scheme to study how RNA controls gene expression in living cells, with the goal of uncovering fundamental principles of RNA biology. www.fmi.ch/news-events/...
Jeff Chao’s group awarded €2.5m ERC grant to study RNA in living cells
FMI senior group leader Jeff Chao and his team have been awarded €2.5 million through the prestigious European Research Council Advanced Grant scheme to study how RNA controls gene expression in livin...
fmi.ch
First pre-print from the lab, a collaborative effort led by Jess Bourn @bournsupremacy.bsky.social, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype? www.biorxiv.org/content/10.6...
Quantitative mapping of heterochrony to species-specific phenotypes
The genetic program of animal development is conserved, but its rate of execution varies across species. Heterochrony, shifts in the relative timing of developmental events, generates phenotypic varia...
biorxiv.org
We’re excited that the FMI is participating in the Doctoral Insights Symposium for the first time! Registration is now open — don’t miss this opportunity to explore top PhD programs in life sciences.
Vienna BioCenter Scientific Training@vbcscitraining.bsky.social · 2mo ago🚀 Doctoral Insights 2026 is HERE. Spotlighting Europe's best fully funded PhD programs in life sciences all summer. Free online Symposium: Sept 10 → doctoralinsights.at Follow along 👇 #DocInsights #LifeSciences #PhD
Looking forward to seeing you all at the #aECM club today!👇
Pujol lab@pujol-lab.bsky.social · 4mo ago👉 3rd aECM club Apr 14th 10 am NYC-4 pm Paris #aECM invertebrate cuticle and molt cycle @gotworms.bsky.social @labgrosshans.bsky.social program sundaramlab.com/blog/aecm-cl... 👉 join our Slack forms.gle/Y6UjbnXPH1pD...
Exciting news: Our RNA community in @uniregensburg.bsky.social is set to grow! We are opening a Junior Group Leader position in RNA biochemistry / ribonucleases / RNA stability. A great opportunity to start your own team within our collaborative RNA network. Details & application 👇
Postdoc positions available in my lab in Aarhus, Denmark on 'Mammalian Nuclear RNA Production and Turnover Systems'. Please get in touch for further information or simply apply here: mbg.au.dk/en/news-and-...
Postdoc positions in Nuclear RNA Biology - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University
mbg.au.dk
Join us 👇. Together with our CompBio and Proteomics platforms, we'd love to work with you on examining protein dynamics!
FMI science@fmiscience.bsky.social · 6mo ago💫 We're hiring! The Computational Biology Facility is looking for a Computational Proteomics Scientist to collaborate on cutting-edge proteomics projects, develop new analytical approaches, and publish impactful research. Apply by April 12 at: www.fmi.ch/education-ca...
🚀 We’re hiring! The Structural Biology Platform is seeking a Project Leader to advance cryo-electron tomography and expand capabilities at the FMI. Join a vibrant research community at the interface of structural biology, cell biology & disease mechanisms. Apply at: www.fmi.ch/education-ca...
👩🔬 On February 11, to mark the International Day of Women and Girls in Science, we’re hosting a panel discussion on how scientific progress and gender equality can advance together. The panel brings together voices from academia, industry, and EDI. Join us for this important conversation! #IDWGS
Now out in @currentbiology.bsky.social: neuroscientists in the lab of @felsenberg.bsky.social found that in fruit flies, re-tasting a sugar reward can weaken past memories, pointing to new ways to safely update harmful ones. www.fmi.ch/news-events/...
How a sweet treat can change memories
Memories must be flexible so animals can adapt when the world changes. FMI neuroscientists found that in fruit flies, simply tasting a sugar reward again can weaken all previous associated memories. T...
fmi.ch
Very thankful for this thoughtful dispatch by @shaisrael.bsky.social sky.social and Moshe Parnas about our work. Learning and memory: Forgetting to remember: Current Biology www.cell.com/current-biol...
FMI science@fmiscience.bsky.social · 6mo agoNow out in @currentbiology.bsky.social: neuroscientists in the lab of @felsenberg.bsky.social found that in fruit flies, re-tasting a sugar reward can weaken past memories, pointing to new ways to safely update harmful ones. www.fmi.ch/news-events/...
Our annual brochure “Year in Review” is out now! It highlights the FMI’s key scientific publications, major events, and facts & figures from 2025, a year that marked our 55th anniversary. www.fmi.ch/news-events/...
FMI Year in Review 2025
Our annual brochure highlighting the FMI’s key scientific publications, major events, and facts & figures from the past year is now available. Discover the highlights of 2025, a year that marked the F...
fmi.ch
Prof. Fiona Doetsch has been awarded the 2026 Louis-Jeantet Prize for Medicine! Her discoveries reveal how neural stem cells support lifelong brain plasticity and repair. 🧠 Read more: www.biozentrum.unibas.ch/news/detail/...
RNA-binding proteins function through network effects, coordinately binding and weakly regulating many transcripts – or don’t they? Read our new preprint on how LIN28 controls developmental timing through only two targets, one mRNA, one miRNA. doi.org/10.64898/202...
Please repost - position of Head of Student & Postdoc Affairs available at our Institute in the heart of Europe (Basel, Switzerland) 👇
FMI science@fmiscience.bsky.social · 8mo ago📢 Please help spread the word: We’re hiring a Head of Student & Postdoc Affairs to coordinate our international PhD program, provide guidance & career counseling, lead training programs, collaborate on EDI initiatives, and manage alumni relations. Apply at www.fmi.ch/education-ca...
Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...
Switzerland is joining Horizon Europe! We are uniting two research powerhouses. For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more. Today is a good day for science, and for our EU-Switzerland partnership.
And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!
Max Perutz Labs Vienna@maxperutzlabs.ac.at · 9mo ago📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
Now in @embojournal.org: Researchers in @labgrosshans.bsky.social & UCSC found that similar molecular machineries control daily circadian rhythms & developmental timing—showing that evolution can repurpose core timing systems to coordinate both daily cycles & growth. www.fmi.ch/news-events/...
One clock, two functions: from daily rhythms to development
Scientists at the FMI and the University of California-Santa Cruz have found that similar molecular machineries control daily circadian rhythms and developmental timing. Their work in worms shows that...
fmi.ch
Here is the schedule for the next TriRhena Gene Regulation Club at the FMI @fmiscience.bsky.social in Basel 🇨🇭 next week (5 Nov 2025; 14:00-18:45). Exciting topics ahead & we are looking forward to the #newPI talks by @julianeg.bsky.social (MPI) & Anupama Hemalatha (FMI). www.ie-freiburg.mpg.de/grc
Nektarios Tavernarakis on why curiosity-driven research, not focusing on application, is fundamental to problem solving and requires government support in @emboreports.org doi.org/10.1038/s443...
For the love of frontier research, or why Elon’s rockets keep blowing up | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
doi.org
Flying worms! www.science.org/content/arti... (And I always wondered how worm cuticular alae (= wings) got their name 😉)
Bull’s-eye! Static electricity pulls worm through air to its insect victim
Electrostatic charges may help roundworms infect a wide variety of hosts
science.org
🔬 Next in the NCCR RNA & Disease Seminar Series: Prof. Olivia Rissland (Univ. of Colorado School of Medicine, USA)! 📅 27.10. 16:30 – University of Bern, DCBP 📅 28.10. 15:00 – ETH Zurich, Hönggerberg 👉 More info: nccr-rna-and-disease.ch/education/nc... @unibe.ch @ethz.ch @snf-fns.ch
For what it’s worth, The Wyoming Worm lab has funding for 5 years along with exciting projects with solid foundations. We are is still looking for capable, dedicated, and fun-to-work-with lab members at all career stages. davidfay@uwyo.edu scholar.google.com/citations?us...
