Léa Swistak
@leaswistak.bsky.social
🇪🇺 | Cellular microbiology | Cryo-ET | EIPOD-LinC postdoctoral fellow Mahamid lab @EMBL | Before PhD in the Enninga lab @InstitutPasteur
Interested in gaining a theoretical foundation along with hands-on practice in Correlative Light and Electron Microscopy (CLEM) in both room temperature and cryogenic conditions? Then join us for #EMBOCLEM 🔬 🧪 s.embl.org/lem27-01-bl EMBL Heidelberg 31 Jan – 5 Feb 2027 Apply by: 25 Oct 2026
Congrats everyone !!
Cell Host & Microbe@cp-cellhostmicrobe.bsky.social · 4mo agoUniversal microbiome signature for CRC Large gut microbiome meta-analysis of colorectal cancer uncovers CRC microbiome signatures universal across ages & sequencing methods & modifiable by dietary interventions, ie fiber. www.cell.com/cell-host-mi...
Margot Sahnine, Dorian Obino and co-workers @pasteur.fr show that N. meningitidis induces membrane protrusions with distinct #F-actin networks in epithelial and endothelial cells. The branched network in endothelia depends on Arf1. #Host-pathogen #membrane -> link.springer.com/article/10.1...
See also our preprint about the microscope itself, which went up earlier this afternoon! www.biorxiv.org/content/10.6...
biorxiv.org
Big news for correlative cryogenic SMLM/ET! With my colleague Soheil, we (Mahamid and @jonasries.bsky.social labs) indicate lamella-specific illumination can allow 500-1500x higher laser intensities, opening massive new possibilities for correlative imaging #teamtomo www.biorxiv.org/content/10.6...
Excited to share that as my group launches across Karolinska Institutet and the University of Helsinki, we’re recruiting postdocs and research assistants to study the nanoscale architecture of lipid flux using in-cell structural biology approaches, including cryo-ET and cryo-CLEM
Congratulations, Julia Mahamid! Julia Mahamid receives the @dfg.de Leibniz Prize for her work on structural cell biology! #LeibnizPreis
Deutsche Forschungsgemeinschaft@dfg.de · 10mo agoUnd hier sind sie – die 10 Preisträger*innen des Gottfried Wilhelm #LeibnizPreis' 2026 – ausgezeichnet für ihre exzellenten Forschungsarbeiten und Errungenschaften in der Wissenschaft! 🏆👏 Die Verleihung der Preise feiern wir am 18. März in Berlin. Einzelheiten & Kurzprofile: sohub.io/1uv1
New paper from my colleague Soheil in the Mahamid and @jonasries.bsky.social groups looking at factors influencing laser devitrification on frozen #cryoem samples. With a far-red fluorophore, all-gold support grids will be especially good for correlative cryo-SMLM and EM! doi.org/10.1016/j.js...
Only 328 days to go! We're very busy behind the scenes getting thigns ready for the meeting! In the meantime you can add your email address for updates here: coming-soon.embo.org/w26-04
Shigella, the first international meeting
coming-soon.embo.org
Diving “Google earth mode 🌍” in a Shigella infected cell 🔬🔎 Together with @m-albert.bsky.social
Institut Pasteur | 130 years of biomedical research@pasteur.fr · last yr.Zoom into a human cell infected by Shigella, the bacteria behind dysentery. Using cryo-EM, @leaswistak.bsky.social and team revealed how it pierces cells with molecular syringes. Stunning science at the nanoscale. @enningalab.bsky.social @jytinevez.bsky.social @nanoimaging.bsky.social #CryoEM
How do intracellular #bacteria breach vacuoles to enter the host cytosol? @leaswistak.bsky.social @matthijnvos.bsky.social @enningalab.bsky.social &co show that #Shigella uses its T3SS system to damage endomembranes via mechanoporation to initiate cytosolic access @plosbiology.org 🧪 plos.io/4jXrr9Z
Great event! Super experience as a speaker/trainer. Looking forward for the next edition 😄
EMBL Events@events.embl.org · 2y agoA big shoutout to all participants, trainers, speakers, and organizers for making last week's #EMBOCLEM such a success! 🙌 Your enthusiasm and curiosity made the course into a great experience for all involved. We hope the new skills and connections will inspire your future research 🥼
