Truly bizarre story of how two papers from the 1940s by physics pioneer Max Planck have been "retracted" from Naturwissenschaften, potentially by an algorithm, for anachronistic "plagiarism" issues, leaving the current editor baffled (but it is Springer Nature so.... www.science.org/content/arti...

Why have papers by one of history’s most famous physicists been retracted?

Springer Nature has removed two studies by Max Planck. A bot may be to blame

science.org

A new pathway to target intracellular pathogens - Listen to Tyler Rhinesmith and Leo James from the LMB’s PNAC Division discuss their new paper on the latest episode of The Naked Scientists podcast: www.thenakedscientists.com/podcasts/nak... #LMBintheNews

UK's under-16 social media ban, and the first trillionaire

Plus, scientists trace the origins of cotton to the Caribbean

thenakedscientists.com

Thermo Fisher now has a page up in response to our observations. They flatly deny that images were manipulated or fabricated while repeating that images were "optimized for presentation and clarity on the website", no lie, six times. www.thermofisher.com/us/en/home/l...

Reese Richardson@reeserichardson.bsky.social · 2mo ago

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

Today I'm posting a new blog about an astonishing scientific own goal. Hundreds of papers have reported using a totally wrong antibody to investigate the tumor suppressor p16. This mistake has happened because scientists have muddled the names of two proteins. forbetterscience.com/2026/06/02/m...

'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.' link.springer.com/article/10.1...

The controls that got out of control - EMBO Reports

EMBO Reports - When experimental controls go wrong, it does not necessarily mean your experiment is flawed. It might well be the first sign of something unexpected.

link.springer.com

Catalogue entries for more than 100 antibodies sold by the research services and supply company Thermo Fisher Scientific contain images that have apparently been manipulated, according to a pair of science sleuths. go.nature.com/4wX4yej

Science sleuths uncover more than 100 suspicious images in Thermo Fisher antibody catalogue

Scientists have long worried about the reliability of commercial antibodies, and the latest findings have sparked fresh concerns.

go.nature.com

Open Postdoc Position - Giant E3 ligases: mysterious mechanisms & non‑protein substrates. Interested? Join us to uncover how these molecular giants tag lipids, RNAs, sugars beyond proteins, on organelles and pathogens, to defend the cell. Details & Application here www.imp.ac.at/career/open-...

Interested in non-proteinaceous ubiquitination, induced proximity or glycogen? Then you should have a look at our newest article, “Ubiquitination of glycogen and metabolites in cells and tissues”, just published in Nature: www.nature.com/articles/s41...

Check out our latest paper on the ubiquitination of glycogen in cells and tissues! Congratulations to Marco Jochem (@marcojochem.bsky.social) and Simon Cobbold for leading this study and to collaborators @craigagoodman1.bsky.social, @pgregorevic.bsky.social, Kai Hofmann and Thomas Hermanns.

Marco Jochem@marcojochem.bsky.social · 4mo ago

Interested in non-proteinaceous ubiquitination, induced proximity or glycogen? Then you should have a look at our newest article, “Ubiquitination of glycogen and metabolites in cells and tissues”, just published in Nature: www.nature.com/articles/s41...

Our lab is looking for a lab technician! If you share our passion for fundamental research and happy to contribute, join us!

Max Perutz Labs Vienna@maxperutzlabs.ac.at · 4mo ago

Pipettes, planning, and protein quality control – sound like your thing? 🧬 Join the @gekaragoz.bsky.social lab and help keep cutting-edge research running smoothly ➡️ tinyurl.com/mw398bzd

We are hiring a new Technical Assistant (M/F/D). The position will be in the Department of Molecular Machines and Signaling. More information below : ❕ Apply until: May 5 ❕ www.linkedin.com/jobs/view/43... #hiring #jobalert #TechnicalAssistant #BTA #MTA #CTA #LabJob

Deadline extended to April 8, 2026!!! Don't miss your chance !!! APPLY NOW: www.imprs-lm.mpg.de/index.php/jo...

New #preprint 😍‼️ led by 2 incredible postdocs @ninizhani.bsky.social & Ranj Papareddy: transforming #UFMylation from a local ribosome rescue pathway to systems level regulator of mRNA splicing www.biorxiv.org/content/10.6... A short 🧵

Congrats Milica @alessandrick.bsky.social & everyone @gekaragoz.bsky.social lab. Glad we could contribute to this awesome story on #UFMylation & #RQC crosstalk @embojournal.org link.springer.com/article/10.1...

The coordinated action of UFMylation and the RQC pathways clears arrested polypeptides at the ER - The EMBO Journal

Clearance of arrested nascent polypeptides resulting from ribosomal stalling is essential for proteostasis. Stalled endoplasmic reticulum (ER)-bound ribosomes are marked by ubiquitin-fold modifier 1 (...

link.springer.com

🆕 publication! The @gekaragoz.bsky.social lab shows how cells clear stalled ribosomes at the ER, preventing harmful 'traffic jams' during protein synthesis🚦Their new @embojournal.org study reveals how quality control and UFMylation team up to keep translation moving ➡️ tinyurl.com/2czj8fvp

📣 Physicists and engineers: apply your experimental skills to biology! Join the group of Katerina Naydenova @imprs-lm.bsky.social for a #PhD to develop new technologies that enable answering fundamental biological questions. Apply NOW!

Interested in uncovering how the #Golgi reacts to stress? Apply NOW to the @hellerschmiedlab.bsky.social @imprs-lm.bsky.social #chembio #cellbio #biochemistry

🔍 Want to uncover how proteolytic enzymes in the ubiquitin system work—and exploit those insights for novel therapeutic approaches? Apply to the Gersch Lab @maltegersch.bsky.social at @imprs-lm.bsky.social. #proteolysis #ubiquitin #biochemistry #proteinchemistry

🚀 Calling all curious minds and future innovators! Are you interested in using DNA nanotechnology to mimic and understand biological systems. APPLY NOW to the group of Prof. Heuer-Jungemann @ameliehj.bsky.social @imprs-lm.bsky.social for a truly interdisciplinary project! #DNAnanotechnology

Receptor clustering is a common theme in viral detection, but whether detection directly hinders genome replication is less clear. Excited to share the Z in RZ-type E3s: ZNFX1 is an RNA helicase that builds ubiquitin chains leading to aggregates that ensnare viral RNA. www.cell.com/molecular-ce...

ZNFX1 uses two-component ubiquitin circuitry to quarantine viral RNA

Squair et al. show that ZNFX1 restricts ssRNA virus replication by integrating SF1 helicase activity with dual E3 ligase mechanisms. ATP-dependent RNA binding activates E3 function, driving self-propa...

cell.com

Such an exciting opportunity! Be among the first to join the brand-new @leokiss.bsky.social lab @unidue.bsky.social 🧬✨ #CellularBiochemistry #Ubiquitin #Proteostasis #ProteinDegradation

IMPRS for Living Matter@imprs-lm.bsky.social · 5mo ago

Excited to decode the intricate language of ubiquitin chains and unravel their role in protein degradation? 🧬🔬 👉 APPLY NOW to join the lab of Dr. Leo Kiss @leokiss.bsky.social @imprs-lm.bsky.social. #CellularBiochemistry #Ubiquitin #Proteostasis #ProteinDegradation

Excited to decode the intricate language of ubiquitin chains and unravel their role in protein degradation? 🧬🔬 👉 APPLY NOW to join the lab of Dr. Leo Kiss @leokiss.bsky.social @imprs-lm.bsky.social. #CellularBiochemistry #Ubiquitin #Proteostasis #ProteinDegradation

Exciting E3 action from Schulman and @bartellab.bsky.social Labs! Massive congrats to @jakobfarnung.bsky.social and @elenaslo.bsky.social for their amazing work!

Jakob Farnung@jakobfarnung.bsky.social · 5mo ago

The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation (TDMD) is now published! 🎉🍾 We, @bartellab.bsky.social and Schulman lab, describe how 2-RNA factors control protein degradation by recruiting an E3 ligase. @mpibiochem.bsky.social www.nature.com/articles/s41...

Just like RNA and protein degradation collaborating in TDMD this work was also a great collaboration of Bartel and Schulman lab. @elenaslo.bsky.social @wyppeter.bsky.social , Daniel Lin, Lianne Blodgett.

Great opportunity to join @hellerschmiedlab.bsky.social @unidue.bsky.social @imprs-lm.bsky.social

IMPRS for Living Matter@imprs-lm.bsky.social · 5mo ago

Interested in uncovering how the #Golgi reacts to stress? Apply NOW to the @hellerschmiedlab.bsky.social @imprs-lm.bsky.social #chembio #cellbio #biochemistry

Excited to announce that FASEB Ignite Career Forum 2026 (preceding FASEB Ubiquitin Mechanisms, Functions, and Therapeutics & Protein Folding in the Cell) is open for registration! Abstract deadline - April 6, 2026 For more details - events.faseb.org/event/Protei... events.faseb.org/event/Ubiqui...

VCP/p97’s accessory adapters (FAF1, FAF2, UBXN7) boost unfolding and subsequent proteasomal degradation. #ubiquitin. Our paper is out now: Science Advances www.science.org/doi/10.1126/...

The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfolding

A group of accessory adapters positions the p97 adapter Ufd1 to boost substrate unfolding and subsequent proteasomal degradation.

science.org

Very exciting work from my colleagues @hemmo-lab.bsky.social to which I could contribute a tiny bit!

Hemmo Meyer Lab@hemmo-lab.bsky.social · 5mo ago

VCP/p97’s accessory adapters (FAF1, FAF2, UBXN7) boost unfolding and subsequent proteasomal degradation. #ubiquitin. Our paper is out now: Science Advances www.science.org/doi/10.1126/...