Leah Greenspan
@ljgreenspan.bsky.social
Developmental biologist using zebrafish to study the mechanisms of acute and chronic cutaneous wound healing
Excited to have started my new lab in Human Genetics at Pitt Public Health! We study wound healing in diabetes & aging using adult zebrafish. Check out this movie showing neutrophil dynamics after injury. Now recruiting research staff, grad students, and postdocs. DM me if interested.
Congrats Jong and Dan! The movies are 🔥
Dan 🐟 C@zebrafish007.bsky.social · 9mo agoExciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park! “Specialized gas-exchange endothelium of the zebrafish gill” — www.biorxiv.org/content/10.6... Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)
Attention all NAVBO Members: Check out “The Vascular Network” - NAVBO’s brand-new members-only social media platform is active!! 🚀 Stay connected and engaged with the vascular biology community and all things at NAVBO! Check out here for more👉 navbo.junolive.com/main/home
Meet Development’s 2025 Pathway to Independence (PI) fellows In a series of interviews published in @dev-journal.bsky.social, we learn more about each fellow’s career path, research interests and aspirations when they start their own lab. thenode.biologists.com/developments...
Development's Pathway to Independence programme: meet the 2025 fellows - the Node
Earlier in 2025, we welcomed our third cohort of Development's Pathway to Independence (PI) fellows - researchers whom we will be supporting as they
thenode.biologists.com
#DevBio #Postdocs! Abstracts are being accepted for speakers in the 2025-2026 Ethel Browne Harvey Postdoctoral Seminar Series. SDB postdoctoral members are eligible to apply. Deadline: August 1. #SDBPostdocSeminar bit.ly/3x1ptgb
Over a decade in the making but excited to have helped bring this paper over the finish line. We generated an endothelial ribotag transgenic line and profiled endothelial cells in larvae and adult organs of zebrafish #zebrafish #DevBio 🧪 Check out our publication: link.springer.com/article/10.1...
If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)
Attention all NAVBO Members: Check out “The Vascular Network” - NAVBO’s brand-new members only social media platform. Launch Date: June 12th 2025 Use it to stay connected and engaged with the vascular biology community and all things NAVBO! Get access here: navbo.junolive.com/main/home
Check out the latest microscopy preprints including our recent favorite tool (LUCID) from #WeinsteinLab 🔥 🔗 to preprint: www.biorxiv.org/content/10.1...
Comprehensive 3D Imaging of Whole Zebrafish Using a Water-Based Clearing Reagent for Hard Tissues
Zebrafish (Danio rerio) is a valuable model organism for studying developmental processes due to its external development and the optical clarity of its embryos and larvae. However, as development pro...
biorxiv.org
FocalPlane @focalplane.bsky.social · last yr.Our latest preprint list is now up on FocalPlane. Our list this week is focusses on research using 🔬microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included. focalplane.biologists.com/2025/05/16/m...
High-resolution optical imaging of the meninges within the brain of an adult zebrafish. Credit to @zebrafish007.bsky.social & #WeinsteinLab. #ZebrafishZunday 🧪
It's been a long time coming and I'm super excited to share our new preprint is out: "A novel transgenic reporter to study vertebrate epigenetics". We generated a zebrafish epigenetic reporter and found a fatty liver disease mutant with weird epigenetic phenotypes 👇 www.biorxiv.org/content/10.1...
Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...
An optogenetic toolkit for robust activation of FGF, BMP, and Nodal signaling in zebrafish
Cell signaling regulates a wide range of biological processes including development, homeostasis, and disease. Accessible technologies to precisely manipulate signaling have important applications in ...
biorxiv.org
Switching fields to #zebrafish? Wanting to become an expert in zebrafish research? Check-out the @mblscience.bsky.social 2025 Zebrafish Development & Genetics course – a fantastic opportunity to learn from leaders in the field! Application deadline: March 13 www.mbl.edu/education/ad...
Congrats to the 2025 SDB Award Winners! Conklin Medal: Blanche Capel DB-SDB Lifetime Achievement Award: Billie Swalla Hamburger Outstanding Educator Prize: Erica Crespi Hay New Investigator Award: Mubarak Syed SDB Trainee Science Communication Award: Joaquin Navajas Acedo bit.ly/4bcrFap
Looking to enhance your timeline for 2025? Check out our Starter Pack of outstanding Group Leaders and Scientists from the #zebrafish community! #WomenInScience go.bsky.app/4BegEjv 🧪
Apply for our Pathway to Independence programme, a scheme supporting postdocs going on the job market in 2025 with training, mentorship, profile-raising and networking opportunities. Apply by 31 Jan 2025: https://buff.ly/3VJGgDC
Merry Fishmas to all, and to all a good feeding! Thanks to all that are taking care of our fish this holiday season 🙏
Looking down at the head of a transgenic 17-day-old #zebrafish, blood vessels in magenta, lymphatic vessels in green. Extended depth of focus #WeinsteinLab 🧪🔬
And somehow I missed it going live last week 😂 - our #zebrafish glial-vascular paper is available for those finterested! One of the best ways to end 2024 as a #newPI www.cell.com/iscience/ful...
Zebrafish glial-vascular interactions progressively expand over the course of brain development
Glial-vascular interactions are critical for the formation and maintenance of brain blood vessels and the blood-brain barrier (BBB) in mammals, but their role in the zebrafish BBB remains unclear. Using three glial gene promoters—gfap, glast, and glastini (a truncated glast)—we explored glial-vascular development in zebrafish. Sparse labeling showed fewer glial-vascular interactions at early stages, with glial coverage and contact area increasing with age. Stable transgenic lines for glast and glastini revealed similar developmental increases, starting at ∼30% coverage at 3 days post-fertilization (dpf) and peaking at ∼60% by 10 dpf, and consistently higher glial coverage in the forebrain and midbrain than in the hindbrain.
cell.com
Development of the nervous system in a #zebrafish larva. Credit to Dr. Nathan Martin of @plavickilab.bsky.social. #ZebrafishZunday 🧪
Let your timeline shine with these outstanding #WomenInScience! 🧪 #zebrafish go.bsky.app/4BegEjv
This is a fantastic program and I highly recommend anyone going on the faculty job market to apply! As part of the first cohort I’m happy to chat about the program. Feel free to DM me if you want to learn more.
Development@dev-journal.bsky.social · 2y agoDelighted to announce a new call for applications for our Pathway to Independence programme. Now entering its third year, this scheme supports postdocs going on the job market in 2025 - with training, mentorship, profile-raising and networking opportunities. Application deadline 31 Jan 2025. 1/3
Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)
#FluorescentFriday #Zebrafish Visualization of neutrophil migration kinetics after tailfin wound at a whole animal scale. We need more research done at a whole-animal scale... so much we don't ask because we're just looking at the small local wound under the 🔬
