Loïc Labache

@loiclabache.bsky.social

Postdoctoral Fellow at Rutgers University Previously CEA 🇫🇷, Yale 🇺🇸 Website: loiclabache.github.io Cognitive neuroscientist and statistician interested in hemispheric specialization 🧠

Hemispheric specialization is core to brain organization, but its biological basis has been unclear. New @holmeslab-bhi.bsky.social paper links neurochemical & cellular asymmetries to left-lateralized language & right-lateralized attention networks, with implications for evolution & psych illness.

Loïc Labache@loiclabache.bsky.social · last mo.

Happy to share that our work is finally published in @commsbio.nature.com! We identify molecular and cellular signatures of hemispheric specialization, linking language and attention to distinct neurotransmitter, mitochondrial, & cellular organization across the cortex 🧠 doi.org/10.1038/s420...

Happy to share that our work is finally published in @commsbio.nature.com! We identify molecular and cellular signatures of hemispheric specialization, linking language and attention to distinct neurotransmitter, mitochondrial, & cellular organization across the cortex 🧠 doi.org/10.1038/s420...

Molecular and cellular correlates of human cortical lateralization - Communications Biology

Multimodal analyses reveal the molecular and cellular asymmetries underlying human cortical lateralization. Distinct neurotransmitter, mitochondrial, and cellular gradients support left-lateralized la...

doi.org

Loïc Labache@loiclabache.bsky.social · last yr.

🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization 🔗 doi.org/10.1101/2025... 🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇 #neuroskyence

🧠 New work showing prominent and widespread 𝘪𝘯 𝘷𝘪𝘷𝘰 pre-synaptic terminal reductions in people with schizophrenia.🧠 nature.com/articles/s41... Strongest effects in left hemisphere, but synaptic loss didn't track with MRI grey matter alterations, but did align with..👇1/4

Widespread synaptic density loss in schizophrenia follows molecular and network architecture - Molecular Psychiatry

Molecular Psychiatry - Widespread synaptic density loss in schizophrenia follows molecular and network architecture

nature.com

Les espèces classiques de la SVT : se reproduisent 🥱 Les reines des fourmis M. ibericus : clonent des mâles d'une autre espèce 🤯 pour se reproduire avec et créer des ouvrières hybrides 😤 tout en faisant des mâles de leur espèce pour faire des nouvelles reines 💃💃 www.nature.com/articles/s41...

One mother for two species via obligate cross-species cloning in ants - Nature

In a case of obligate cross-species cloning, female ants of Messor ibericus need to clone males of Messor structor to obtain sperm for producing the worker caste, resulting in males from the same moth...

nature.com

Excited to share that our work is now published in Imaging Neuroscience! 🧠🥳 We show how aging reshapes the brain’s language and memory networks, revealing striking shifts in hemispheric specialization across the lifespan. Check it out @imagingneurosci.bsky.social

Imaging Neuroscience@imagingneurosci.bsky.social · last yr.

New paper in Imaging Neuroscience by Elise Roger, Gaelle E. Doucet, et al: When age tips the balance: A dual mechanism affecting hemispheric specialization for language doi.org/10.1162/IMAG...

The molecular and cellular basis of human brain lateralization. Latest paper from @holmeslab-bhi.bsky.social led by @loiclabache.bsky.social. @rutgersbhi.bsky.social, @cahbir.bsky.social

Loïc Labache@loiclabache.bsky.social · last yr.

🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization 🔗 doi.org/10.1101/2025... 🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇 #neuroskyence

Until recently, in-vivo brain imaging has largely been absent from… integrative efforts, limiting the opportunities to contribute our discoveries, theories or vision toward a comprehensive view of brain function, writes @avramholmes.bsky.social. #neuroskyence www.thetransmitter.org/future-of-fm...

fMRI must break out of its silo

We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

thetransmitter.org

🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia" medrxiv.org/content/10.1... We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇

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