Do brain connections just carry information between regions, or do they transform it? Lab's latest is out in Nature Neuroscience, led by Lakshman Chakravarthula: "Network geometry shapes the transformation of task representations across the human cortex" www.colelab.org/pubs/Chakrav... 1/n

"Left hemisphere for Language, the right for attention,” that’s the textbook story of hemispheric complementarity. In 987 HCP participants, we find it describes only some brains. The alternatives are heritable and structurally grounded. New @holmeslab-bhi.bsky.social paper by @loiclabache.cpesr.fr

Loïc Labache@loiclabache.cpesr.fr · 4w ago

🚨 Language is usually left-lateralized, while attention tends to favor the right hemisphere. But are these functions always on opposite sides of the brain?🧠 In our new @biorxiv-neursci.bsky.social preprint, we explored hemispheric complementarity in 987 people. 🧵 www.biorxiv.org/content/10.6...

🚨 Language is usually left-lateralized, while attention tends to favor the right hemisphere. But are these functions always on opposite sides of the brain?🧠 In our new @biorxiv-neursci.bsky.social preprint, we explored hemispheric complementarity in 987 people. 🧵 www.biorxiv.org/content/10.6...

Hemispheric Complementarity is Associated with Distinct Functional and Structural Brain Profiles

Hemispheric specialization is thought to follow a principle of complementarity, with homotopic functions such as language and attention lateralizing to opposite hemispheres, yet its consistency across...

biorxiv.org

⚠️ Preprint alert ⚠️ How does the brain's fixed anatomy support flexible function? We explore this using recurrent neural networks with increasing levels of brain-like constraints, comparing them to empirical fMRI activity. (1/8) www.biorxiv.org/content/10.6...

Geometric constraints and cognitive inputs jointly shape emergent brain dynamics and topology

How the brain's physical geometry gives rise to its flexible functional repertoire remains a central question in neuroscience. Here, we trained three classes of recurrent neural networks (RNNs) on a w...

biorxiv.org

So excited to share that our study is out now in @natcomms.nature.com! 🧠🚨 www.nature.com/articles/s41... Big shout out to coauthors @sidchop.bsky.social @ashleasegal.bsky.social @loiclabache.bsky.social Rowena Chin Kaley Joss & @avramholmes.bsky.social

Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease - Nature Communications

Cocuzza et al. show that brain network dynamics are less flexible in psychiatric illness, and these patterns predict individual symptom profiles better than diagnoses, highlighting brain dynamics as a...

nature.com

Hemispheric specialization is core to brain organization, but its biological basis has been unclear. New @holmeslab-bhi.bsky.social paper links neurochemical & cellular asymmetries to left-lateralized language & right-lateralized attention networks, with implications for evolution & psych illness.

Loïc Labache@loiclabache.cpesr.fr · 4mo ago

Happy to share that our work is finally published in @commsbio.nature.com! We identify molecular and cellular signatures of hemispheric specialization, linking language and attention to distinct neurotransmitter, mitochondrial, & cellular organization across the cortex 🧠 doi.org/10.1038/s420...

Happy to share that our work is finally published in @commsbio.nature.com! We identify molecular and cellular signatures of hemispheric specialization, linking language and attention to distinct neurotransmitter, mitochondrial, & cellular organization across the cortex 🧠 doi.org/10.1038/s420...

Loïc Labache@loiclabache.cpesr.fr · 2y ago

🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization 🔗 doi.org/10.1101/2025... 🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇 #neuroskyence

🧠 New work showing prominent and widespread 𝘪𝘯 𝘷𝘪𝘷𝘰 pre-synaptic terminal reductions in people with schizophrenia.🧠 nature.com/articles/s41... Strongest effects in left hemisphere, but synaptic loss didn't track with MRI grey matter alterations, but did align with..👇1/4

Widespread synaptic density loss in schizophrenia follows molecular and network architecture - Molecular Psychiatry

Molecular Psychiatry - Widespread synaptic density loss in schizophrenia follows molecular and network architecture

nature.com

Do humans show sex differences in brain activation? If so, are these task-specific or general — and do they relate to sex differences in brain anatomy and behavior? We dove deep into these questions in a new paper just out in Nature Communications | tinyurl.com/3rdrb524

Did we just discover that association cortex has...associations?

Once upon a time I just admired nudis and sea slugs. But it was not enough. Now apparently I'm creating an R package to celebrate their colour palettes? 😅 First up, my Sydney fave, Hypselodoris bennetti. #rstats #nudibranch #dataviz 🦑🐙🧪 #marinelife #invertebrates

Now out in Psychological Medicine! We identified lifetime exposures to humiliation and entrapment, as well as frontoparietal-left cerebellar RSFC, as correlates of adolescent anxiety and depression symptoms across three time points. Link: doi.org/10.1017/S003...

neuroAI comparisons of ANNs to brains do have a range of problems. Even more than I had realized. And I was worried before: www.biorxiv.org/content/10.1...

Our latest work on the neurobiology of subjective emotional experience in anxiety is out now in SCAN 🧠 Brief summary below 👇 doi.org/10.1093/scan...

Linking subjective experience of anxiety to brain function using natural language processing

Abstract. Research on anxiety focuses on clinically relevant behaviours and neurophysiological responses, particularly emphasizing recruitment of amygdala,

doi.org

Spread the word: new PhD track in Biomedical Informatics and Health AI - enrollment for Fall 2026 closing soon! www.linkedin.com/feed/update/...

@ohbmofficial.bsky.social, Is the new OHBM abstract length really 14,000 characters?

The Organization for Human Brain Mapping@ohbmofficial.bsky.social · 11mo ago

⏳ Just 2 weeks left to submit for #OHBM2026! Be part of shaping the scientific program in Bordeaux, France. ⏰ Deadline: December 15, 2025, at 11:59 pm EST, USA #Neuroimaging #BrainMapping

@ohbmofficial.bsky.social, is the new OHBM abstract length really 14,000 characters? This would mean a shift from an abstract to a conference paper. If so, what are the implications for publication rights with respect to journal submissions? How are reviewers expected to review up to 40?

The Holmes Lab is #hiring a full-time research assistant/predoc! Our work focuses on functional brain networks-- how they change, how they are impacted in psychiatric illness, and much more! Please rt and reach out if you’re interested 👀 Find out more holmeslab.rutgers.edu

Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness? @holmeslab-bhi.bsky.social is hiring! @cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social

One to watch! 👇🏼🔥 Be sure to tune in Monday for the live event or check out the recording on youtube, along with all our WBHI lectures. Register for the full series at wbhi.ucsb.edu/about/events We’ve got an amazing 25-26 lineup.

The Ann S. Bowers Women's Brain Health Initiative@bowers-wbhi.bsky.social · last yr.

Join us this Monday, September 8, 2025 at 2pm PDT/5pm EDT as Winnie Orchard, PhD and Scientific Program Director at the Ann S. Bowers Women's Brain Health Initiative, dives into “Developing the Gold STANDARD: a Standardized Tool for Acquiring Reproductive Health Data” #BowersWBHI #Neuroendocrinology

Les espèces classiques de la SVT : se reproduisent 🥱 Les reines des fourmis M. ibericus : clonent des mâles d'une autre espèce 🤯 pour se reproduire avec et créer des ouvrières hybrides 😤 tout en faisant des mâles de leur espèce pour faire des nouvelles reines 💃💃 www.nature.com/articles/s41...

One mother for two species via obligate cross-species cloning in ants - Nature

In a case of obligate cross-species cloning, female ants of Messor ibericus need to clone males of Messor structor to obtain sperm for producing the worker caste, resulting in males from the same moth...

nature.com

New paper in Imaging Neuroscience by Elise Roger, Gaelle E. Doucet, et al: When age tips the balance: A dual mechanism affecting hemispheric specialization for language doi.org/10.1162/IMAG...

Excited to share that our work is now published in Imaging Neuroscience! 🧠🥳 We show how aging reshapes the brain’s language and memory networks, revealing striking shifts in hemispheric specialization across the lifespan. Check it out @imagingneurosci.bsky.social

Imaging Neuroscience@imagingneurosci.bsky.social · last yr.

New paper in Imaging Neuroscience by Elise Roger, Gaelle E. Doucet, et al: When age tips the balance: A dual mechanism affecting hemispheric specialization for language doi.org/10.1162/IMAG...

Holmes Lab is representing at #OHBM2025! 🧵 Loic @loiclabache.bsky.social presented in the Language: Anatomy, Networks and Pathology section with his paper on "The molecular and cellular underpinnings of human brain lateralization" 🧠

🚨 Dataset & Manuscript alert! 🚨 The Transdiagnostic Connectome Project (TCP) manuscript is now available @natureportfolio.nature.com Scientific Data! 🎉 www.nature.com/articles/s41... 🧵1👇

The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry - Scientific Data

Scientific Data - The Transdiagnostic Connectome Project: an open dataset for studying brain-behavior relationships in psychiatry

nature.com

🚨Preprint!🚨 So excited to share my 1st major study as a postdoc at @holmeslab-bhi.bsky.social!🤘 www.biorxiv.org/content/10.1... Using a transdiagnostic framework, we found that brain network dynamics were able to discriminate individualized psychiatric symptom profiles with high accuracy 🧵1/9👇

🎨🧑‍🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊 anniegbryant.github.io/subcortex_vi...

Check our latest work ‘Linking Subjective Experience of Anxiety to Brain Function using Natural Language Processing’. Our analyses link movie-evoked brain activity and subsequent interview recordings in a pediatric sample with and without anxiety disorders (doi.org/10.31234/osf...).

Excited to share the first major piece of work and preprint from my lab! Led by Jason Kim! 🥳🎉🤘 www.biorxiv.org/content/10.1...

a man applauds with the words so proud of my team above him

ALT: a man applauds with the words so proud of my team above him

media.tenor.com

Newest #preprint from Holmes lab postdoc @loiclabache.bsky.social 🔥

Loïc Labache@loiclabache.cpesr.fr · 2y ago

🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization 🔗 doi.org/10.1101/2025... 🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇 #neuroskyence