A consensus atlas of human brain development defines cell type-specific maturation trajectories across the lifespan https://www.biorxiv.org/content/10.64898/2026.07.16.738788v1

*Are rodents a good model of the amygdala?* Probably not. Important comparative anatomy findings by Freixes, Medina, Desfilis. At the VI international Congress of Psychobiology, Seville, Spain.

Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...

Conservation and alteration of mammalian striatal interneurons - Nature

An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...

nature.com

The first single-cell three-dimensional lamprey brain atlas reveals that the vertebrate common ancestor already had a highly regionalized brain, and subsequent neuronal specialization likely drove vertebrate brain diversification. Learn more this week in Science: https://scim.ag/4whLqXp

𝗠𝗮𝗷𝗼𝗿 𝗱𝗲𝗽𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝘁𝗵𝗲 𝗹𝗲𝗻𝘀 𝗼𝗳 circuit 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 Finally research is considering the functional/ anatomical complexity of the brain. It's not about regions, but how circuits function dynamically. www.cell.com/neuron/abstr... #neuroskyence

The first paper from my postdoc is out now in @natneuro.nature.com! We took a multi-model approach to screen 23 neurodevelopmental disorder risk genes for points of convergence in gene expression (in cell culture) and behavior (in #zebrafish) >

Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo - Nature Neuroscience

By studying 23 neurodevelopmental disorder genes across model systems and brain cell types, the authors uncovered shared downstream effects that converge on synaptic biology, epigenetic regulation and...

nature.com

What has changed in mama bear brain (well, actually mice) to make her risk her life to attack a potential threat and protect her young? Oxytocin is the key! Happy to share our new study led by two awesome postdocs: Takashi Yamaguchi and Rongzhen Yan. www.nature.com/articles/s41...

The neural mechanisms supporting the rise and fall of maternal aggression - Nature

In mice, female aggression is governed by an amygdala–to–medial hypothalamus circuit that is strengthened during pregnancy and is dynamically amplified by oxytocin during lactation.

nature.com

Very happy to see our paper on postnatal plasticity in the amygdala of juvenile swine published, with Júlia Freixes and Ester Desfilis @edesfilis.bsky.social and myself as coauthors: link.springer.com/article/10.1...

Postnatal plasticity in the paralaminar nucleus of the pallial amygdala in juvenile swine brain - Brain Structure and Function

Brain Structure and Function - The aim of this study was to investigate the presence of immature cells and their phenotype in the pallial amygdala of juvenile swine brains by way of...

link.springer.com

¡Ayer inauguramos “Gaza, la mirada no silenciada” en Las Palmas! Una exposición que nos invita detenerse y mirar con atención. Una exposición que no busca explicar Gaza con cifras, sino mirarla a los ojos... 📍Centro de Cultura Audiovisual 🗓️ Hasta el 30 de abril

Excited to share our new paper: We uncover a locus coeruleus→amygdala circuit linking β-adrenergic signaling to transcription regulation in defined amygdala cells during memory reconsolidation—+ stress or elevated noradrenergic signaling at recall can strengthen memory. www.cell.com/neuron/abstr...

A neuromodulatory circuit-to-molecular pathway for reformatting aversive memories during recall

Tan et al. identify a neuromodulatory circuit-to-molecular pathway in rats that updates aversive memories when they are recalled. Noradrenaline from the locus coeruleus triggers synapse-to-nuclear tra...

cell.com

el apoyo a las familias afectadas y el impulso a la investigación científica que permita mejorar el diagnóstico, el tratamiento y la calidad de vida de quienes conviven con estas patologías. #diamundialenfermedadesraras #rarediseasesday

Muy orgullosa de formar parte de este equipazo de investigación que estudia una enfermedad ultrarrara #Laforadisease, para dilucidar sus mecanismos moleculares y encontrar un tratamiento. #FEDER_ONG @rarascsic.bskysocial @ibv-csic.bsky social #diamundialdelasenfermedadesraras #rarediseasesday

New lab preprint! Can we study conscious perception of gut sensations in mice to reveal its neuronal basis? Can we train mice to report their gut sensations? Omer Rafael and Stav Shtiglitz in the lab teamed up to discover that…YES! Thread…1/6 www.biorxiv.org/content/10.6...

#HaceOchoAños Isabelle Rapin, la neuropediatra que libró a las madres de la culpa del autismo Un artículo de Rocío Benavente

Isabelle Rapin, la neuropediatra que libró a las madres de la culpa del autismo - Mujeres con ciencia

Isabelle Rapin. Neuropediatría. Trastorno del espectro autista. Problema biológico. Comportamiento de los progenitores. Enfermedad. Síntomas. Desórdenes neurológicos y metabólicos.

mujeresconciencia.com

New paper presenting rather compelling evidence that the stem-vertebrate Haikouichthys had paired lateral and supranumerary medial eyes (!!!), and proposing that the medial eyes may have deep homology with the pineal and parapineal organs. www.nature.com/articles/s41...

Four camera-type eyes in the earliest vertebrates from the Cambrian Period - Nature

Early vertebrates, particularly myllokunmingids, possessed four camera-type eyes (a pair of lateral eyes and pineal and parapineal organs), which indicates that these structures functio...

nature.com

New Year, new paper from our lab. Emily Kramer used 3D light-sheet imaging and tissue clearing to examine the spatial architecture of mouse amygdala engram ensembles. onlinelibrary.wiley.com/doi/10.1002/...

Examining the Three‐Dimensional Spatial Architecture of Mouse Amygdala Engram Ensembles

Memories are stored in a sparse population of neurons active at the time of an event, an engram ensemble, and reactivation of the engram ensemble drives memory recall. Although the amygdala is essent...

onlinelibrary.wiley.com

New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . “Rethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧵 rdcu.be/eVZ1A

Rethinking the centrality of brain areas in understanding functional organization

Nature Neuroscience - Parcellation of the cortex into functionally modular brain areas is foundational to neuroscience. Here, Hayden, Heilbronner and Yoo question the central status of brain areas...

rdcu.be

1/4 Thrilled to be sharing new work published today in Nature describing the third wave of results from the PGC Cross-Disorder Group. This reflects a massive group effort to examine shared and unique genetic signal across >1 million cases for 14 psychiatric disorders. www.nature.com/articles/s41...

Mapping the genetic landscape across 14 psychiatric disorders - Nature

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders...

nature.com

Our special issue on Evolutionary Functions of Consciousness, coedited with Tecumseh Fitch and Adina Roskies, now online royalsocietypublishing.org/toc/rstb/202... Contributions by (1) Irina Mikhalevich; (2) Eva Jablonka and Simona Ginsburg; (3) Nicholas Humphrey; (cont'd)

Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1939

royalsocietypublishing.org

New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬 An amazing set of resources for all scientists working on the brain! 🧠 Immersive feature: www.nature.com/immersive/d4... 🧠 Perspective: www.nature.com/articles/s41...

I am thrilled to share our latest work: we identified a population of central amygdala neurons that promote the earliest and perhaps most important social behavior: pup suckling!... We also developed new tools for pup neuroscience Work by @Jeff Moore now at USC, a collaboration with @Sam Pfaff lab

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 11mo ago

A genetically-defined population of amygdalofugal neurons promotes suckling and early postnatal growth https://www.biorxiv.org/content/10.1101/2025.10.18.683193v1

El pianista Chucho Valdés (1941) cumple hoy años www.youtube.com/watch?v=Jqg5...

Bebo Valdés & Chucho Valdés.- Tres palabras

YouTube video by Calle54Records

youtube.com

Excited to share our latest preprint led by @jarildy.bsky.social looking at social and non social reward representations. www.biorxiv.org/content/10.1.... with help from @hyma2194.bsky.social and @jennisisaac.bsky.social.

Non-overlapping social and food reward representations in the basolateral amygdala

The ability to consider and appraise positively valenced stimuli in the environment, such as food and social interaction, to guide appropriate action is important for survival of most animals. Several...

biorxiv.org

Happy to share our new article with Júlia Freixes, Fatma Abdel-Rahman, Roberto Nebbia and @edesfilis.bsky.social on postnatal plasticity in olfactory areas of the juvenile swine, published in Brain, Structure and Function link.springer.com/article/10.1...

Postnatal plasticity in the olfactory system of the juvenile swine brain - Brain Structure and Function

Swine have an excellent sense of smell and highly complex olfactory brain structures, which play a crucial role in their complex social interactions. In other mammals the olfactory system is known to exhibit significant plasticity, even during adulthood. The aim of this study was to investigate postnatal plasticity in olfactory areas of juvenile swine brains by studying immature cells immunoreactive for the microtubule-associated protein doublecortin (DCX). Using immunofluorescence, we studied DCX coexpression with the cell proliferation marker Ki-67, and different neuronal markers. Our results show the existence of numerous DCX + cells throughout the olfactory pallial areas. In some of them, we found DCX+/Ki-67 + coexpressing cells, suggesting that they were proliferating. Some of these proliferating cells were grouped in tangentially-oriented migratory-like chains, forming the rostral migratory stream to anterior olfactory area and olfactory bulb. Moreover, chains of DCX + cells were found in the external capsule and white matter adjacent to the temporal horn of the ventricle. Chains of DCX + cells were observed crossing the internal layers of the piriform and entorhinal cortices. In layer II of these cortices, DCX + cells of varying maturity degrees and neuronal phenotypes (including NeuN expression) were present. This suggests the existence of multiple migratory streams along the anteroposterior axis. Most DCX + immature cells in the migratory chains and in the anterior olfactory area, piriform and entorhinal cortices expressed the transcription factor Brn2 (Pou3f2), suggesting the incorporation of new glutamatergic neurons in these areas. Together, these results highlight the interest of swine to study the role of postnatal brain plasticity and their potential for regeneration in large, gyrencephalic brains.

link.springer.com

The interoceptive origin of reinforcement learning This Review article represents a true quest for the Holy Grail: the origin of reward! In short, reward originates deep within our bodies, in our viscera, and not in the external environment! www.sciencedirect.com/science/arti... 1/n

Very excited to share my second postdoc, now out in Science Advances! We used targeted snRNA-seq to profile four major subnuclei of the primate across three species (including humans). 1/13 www.science.org/doi/10.1126/...

Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates

Specialized cell types and links to psychiatric disorders are revealed by genetic mapping of primate amygdala neurons.

science.org

Sad day for peope who still believe brain areas are the primary organizational units of function in the brain. www.nature.com/articles/s41...

A brain-wide map of neural activity during complex behaviour - Nature

The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...

nature.com

First day of the #senc 20th meeting in Las Palmas de Gran Canaria. This morning it has been a great symposium of the neuroevodevo PRamón Network, paying tribute to Prof. Rudolf Nieuwenhuys. Congratulations to the organizers @loretamedinah.bsky.social and Nerea Moreno and to all speakers!

Remarkable. Uncontrollable laughing or crying can happen *without* emotion ("pseudobulbar affect"). Here's a video of one individual whose crying is triggered by real or imagined rubbing of his finger & thumb. Intense response but not sadness. /1 static-content.springer.com/esm/art%3A10...

1 To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised! 🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...