My 3-year old just handed me my phone, pointed to it and said "I want to see something die". Good times.
Luke Jostins-Dean
@lukejostins.bsky.social
Data scientist at Nightingale Health, associate professor at University of Oxford
This might be the first time I have seen a pre-pre-print QR code. From @eliseneedham.bsky.social 's lovely talk on phosQTLs at #ESHG26
Coconut dropped from the roof of a house coconut dropped from the roof of a house
Adam Rutherford@adamrutherford.bsky.social · 4mo agoPineapple Migraine
I believe we can drive biomedicine forward by giving the right tools to the right people. That idea is what led me to build CRAM2Excel, a new HTSlib/SAMtools plugin that exports CRAM alignments directly into native Excel workbooks. github.com/asazonov/cra...
Such a strange annual ritual
European Society of Human Genetics@eshg.bsky.social · 6mo agoAbstract submission deadline extended to Monday, February 16, 23:59 hrs CET (no exceptions). Last chance to submit an abstract for inclusion in the programme of #eshg2026 #hybridconference! More information on: 2026.eshg.org/abstracts/
Join UK Biobank for a webinar on Nightingale Health metabolomic data from all half a million participants. Our Principal Scientist, @lukejostins.bsky.social, will co-host the webinar. 🗓️ 21 January 2026, 3:00PM - 4:00PM GMT 🔔 Register: events.ringcentral.com/events/webin...
We have a webinar next week with @ukbiobank.bsky.social on the Nightingale metabolomics data. We did a table read today, and it is shaping up really nicely. Please do come! 300 people have registered already and there are only np.inf spaces left! www.ukbiobank.ac.uk/use-our-data...
Our webinar “Multiomic insights into human disease” by @lukejostins.bsky.social is tomorrow! Join us on 3 December at 3 p.m. CET for an exploration of how integrating proteomics and metabolomics can deepen our understanding of human health and disease. Sign up: www.lyyti.fi/reg/webinar-...
🚨 New preprint from the lab! We’re excited to share “Improving population-scale disease prediction through multi-omics integration” by Ng et al. www.medrxiv.org/content/10.1...
"The idea of deporting people with settled status is disgusting, and anyone proposing it should be immediately drummed out of polite society. Breaking promises made in good faith to our friends and neighbours is racist, extremist and immoral." I'm basically shouting at the sky here, but still.
It’s racist, it’s extremist and it’s immoral
The right is still calling for deportations, and the government is still being cowardly about it. Also: London’s first green belt; some notes on a shark; and some news, on my next book.
jonn.substack.com
This project is in close collaboration with the amazing @lukejostins.bsky.social, and the student will benefit from a multi-disciplinary team! 🌟🧬🧠
Yang Luo@y-luo.bsky.social · 12mo ago🎓 New PhD opportunity in our lab @kiroxford.bsky.social @oxforduni.bsky.social We're exploring host–microbiome genetic interactions in IBD using population-scale data 🧬🦠 🔗 kennedy.ox.ac.uk/.../deciphering-host2013microbiome-genetic-interactions-in-inflammatory-bowel-disease #PhD #Genetics
Parquet works really well with R as well. I use it all the time to work with GWAS summary statistics that won't fit into memory (our latest metabolite GWAS tested 95M+ variants in UKBB). Here's a minimal example of how to filter data on the fly while reading into R: gist.github.com/kauralasoo/f...
Filtering parquet files with dplyr
GitHub Gist: instantly share code, notes, and snippets.
gist.github.com
🎓 New PhD opportunity in our lab @kiroxford.bsky.social @oxforduni.bsky.social We're exploring host–microbiome genetic interactions in IBD using population-scale data 🧬🦠 🔗 kennedy.ox.ac.uk/.../deciphering-host2013microbiome-genetic-interactions-in-inflammatory-bowel-disease #PhD #Genetics
kennedy.ox.ac.uk
Novartis & Roche collaborated w/ Oxford researchers at the Big Data Institute 2 develop AI model using largest collection of clinical trial data (Novartis-Oxford MS dataset) from >8000 ppl living w/ multiple sclerosis (MS) to reclassify the progression of MS www.ndm.ox.ac.uk/news/using-a... #biosky
Both sides of this debate made me feel very warmly about the people of France. www.theguardian.com/society/2025...
Call to ban ‘intolerant’ child-free resorts and hotels in France
Debate grows as Senator Laurence Rossignol says ‘we can’t organise society by separating children off’
theguardian.com
Welcome to our webinar “Multi-omic insights into human disease” by @jeffbarrett.eu on 4 September at 3 p.m. CEST! Join us for an exploration of how integrating proteomics and metabolomics can deepen our understanding of human health and disease. Learn more and sign up: www.lyyti.fi/reg/multiomi...
Amazing news! Excited to be part of this new direction of research.
Kennedy Institute of Rheumatology@kiroxford.bsky.social · last yr.Huge news! A £50M MRC CoRE will bring together Manchester & Oxford to study how environmental exposures cause chronic inflammatory disease. The CoRE will be Directed by Prof Judi Allen (Manchester) & co-Directed by Prof Dame Fiona Powrie, Director of the KIR. www.kennedy.ox.ac.uk/news/new-ps5...
🚨New preprint just dropped 🚨 medrxiv.org/content/10.1101/2025.06.24.25330216 The main output from my PhD is finally public and we’re SUPER excited about the findings! If you’re interested in what we learnt about IBD with a massive 700+ sample sc-eQTL dataset of the gut, read on!
To see which of these underpin susceptibility, we colocalised these with IBD GWAS. Remarkably, we nominate effector genes at an enormous 74 (❗) loci where one has not previously been nominated in @OpenTargets. This therefore SUBSTANTIALLY improves on previous efforts. 10/
Job alert ‼️ @thomasdwkim.bsky.social and I are recruiting a postdoc in single-cell genomics via the NORPOD program of the @nordicembl.bsky.social. Collaboration between @fimm-uh.bsky.social and @dandrite.bsky.social on multimodal data integration in neurodevelopment. jobs.helsinki.fi/job/Helsinki...
Postdoctoral Researcher in Single-Cell Genomics through the NORPOD program
Postdoctoral Researcher in Single-Cell Genomics through the NORPOD program
jobs.helsinki.fi
My 7-year-old just made a knife out of Lego, and did this: "I have a knife!" *Does a few slashes, then poses in a fighting stance" "and I am going to a gun fight" Is this from something, or did he make it up himself?
📢 📢Job alert!📢📢 We have an exciting opportunity for a 4 year post-doc in my lab at @crick.ac.uk. This project will take a similar approach to our recent ETS2 paper, published in Nature, to better understand the mechanisms that contribute to IBD tinyurl.com/yx43upnk
Postdoctoral Fellow - Lee Lab
Salary for this Role: From £45,500 with benefits, subject to skills and experience. Job Title: Postdoctoral Fellow - Lee Lab Reports to: James Lee [C] Closing Date: 23.59 GMT Job Description: Job titl...
tinyurl.com
If you are interested to know why I have been weighing out 15 grams of butter for my bread, and what it has to do with the metabolomics of aging, sign up to this webinar tomorrow
Nightingale Health@nightingalehealth.com · last yr.📣 Our webinar “Measuring the effects of aging with metabolomic profiling” by @lukejostins.bsky.social is tomorrow! Remember to sign up and join us tomorrow at 3 p.m. CEST. Sign up: www.lyyti.fi/reg/aging_we...
📣 Our webinar “Measuring the effects of aging with metabolomic profiling” by @lukejostins.bsky.social is tomorrow! Remember to sign up and join us tomorrow at 3 p.m. CEST. Sign up: www.lyyti.fi/reg/aging_we...
We have 2-3 group leader positions opening @fimm-uh.bsky.social !! We are looking for outstanding candidates in human genetics and precision medicine. This time we have a focus on population health data science. E.g. AI for EHR/health data Generous starting package 💰 shorturl.at/FAk6n
FIMM-EMBL Group Leaders in Molecular Medicine
FIMM-EMBL Group Leaders in Molecular Medicine
jobs.helsinki.fi
NB: The Polygenic Score Catalog has just lost its NIH funding. It was substantial. We are now on auxillary funding sources. If anyone has a spare £1m plz DM
Considering a return to study in the life/environmental sciences at Masters/PhD level after time away? Working and wondering if full/part-time study is the next step for your career? Our RePOWER workshop on 13th June in Oxford/online will provide advice and support. iles.web.ox.ac.uk/repower-retu...
RePOWER: Returning to Postgraduate Study in the Life and Environmental Sciences
iles.web.ox.ac.uk
